Browsing by Author "8c7b98c9-0740-4ab6-94b2-6ed9dc885507"
Now showing items 1-4 of 4
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Miranda, Melissa; Fuenzalida, Karen; Rosen, Clifford J.; Seitz, Germán; Rodríguez, J. Pablo (Wiley-Blackwell, 2016)Bone marrow adipose tissue (BMAT) is associated with low bone mass, although the functional consequences for skeletal maintenance of increased BMAT are currently unclear. BMAT might have a role in systemic energy metabolism, ...
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Xian, Lingling; Wu, Xiangwei; Pang, Lijuan; Lou, Michael; Rosen, Clifford J.; Qiu, Tao; Crane, Janet; Frassica, Frank; Zhang, Liming; Rodriguez, Juan Pablo; Jia, Xiaofeng; Yakar, Shoshana; Xuan, Shouhong; Efstratiadis, Argiris; Wan, Mei; Cao, Xu (2012)Insulin-like growth factor 1 (IGF-1), the most abundant growth factor in the bone matrix, maintains bone mass in adulthood. We now report that IGF-1 released from the bone matrix during bone remodeling stimulates osteoblastic ...
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Román, Flavia; Urra, Carla; Porras Espinoza, Omar; Pino, Ana María; Rosen, Clifford J.; Rodríguez, Juan Pablo (Wiley-Liss Inc., 2017)© 2016 Wiley Periodicals, Inc. Oxidative stress (OS) derived from an increase in intracellular reactive oxygen species (ROS) is a major determinant of aging and lifespan. It has also been associated with several age-related ...
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Li, Xiaojuan; Shet, Keerthi; Xu, Kaipin; Rodríguez, Juan; Pino, Ana María; Kurhanewicz, John; Schwartz, Ann; Rosen, Clifford (Elsevier Inc., 2017)There are increasing evidences suggesting bone marrow adiposity tissue (MAT) plays a critical role in affecting both bone quantity and quality. However, very limited studies that have investigated the association between the ...