Browsing by Author "8eaae10f-f95f-4d3a-8713-c06909fd9eaa"
Now showing items 1-13 of 13
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Pastene, Edgar; Gómez, Maritza; Speisky Cosoy, Hernán; Núñez Vergara, Luis (Sociedade Brasileira de Quimica, 2009)An apparatus which allows the direct measurement of the antioxidant capacity of volatiles compounds emitted from some herbs and culinary spices is described. The device comprises: a sample chamber, a mixing chamber, a pump ...
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Carrasco Pozo, Catalina; Speisky Cosoy, Hernán; Brunser, Oscar; Pastene, Edgar; Gotteland, Martin (2011)The stability of an apple peel polyphenol extract (APPE) with powerful antioxidant activity was evaluated under acidic conditions in vitro, and its protective effect against gastrointestinal damage was investigated in rats ...
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Pastene, Edgar; Troncoso, Miriam; Figueroa, Guillermo; Alarcón, Julio; Speisky Cosoy, Hernán (2009)Apple peel extracts and their fractions pooled according to their molecular size were prepared and evaluated for their inhibitory activity against Helicobacter pylori and Jack bean ureases. Urease Inhibitory effect of apple ...
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Speisky Cosoy, Hernán; Gómez, Maritza; Carrasco Pozo, Catalina; Pastene, Edgar; López Alarcón, Camilo; Olea Azar, Claudio (2008)Cu(2+) ions and and GSH molecules interact swiftly to form the complex Cu(I)–glutathione. We investigated the potential capacity of such complex to reduce molecular oxygen. The addition of SOD to a solution containing ...
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Wong, Ximena; Carrasco Pozo, Catalina; Escobar, Elizabeth; Navarrete Wallace, Paola; Blachier, Francois; Andriamihaja, Mireille; Lang, Annaig; Tome, Daniel; Cires, María José; Pastene, Edgar; Gotteland, Martin (Amer Chemical Society, 2016)The protective effect of proanthocyanidin-containing polyphenol extracts from apples, avocados, cranberries, grapes, or proanthocyanidin microbial metabolites was evaluated in colonic epithelial cells exposed to p-cresol, ...
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Pastene, Edgar; Speisky Cosoy, Hernán; García, Apolinaria; Moreno, Jessica; Troncoso, Miriam; Figueroa, Guillermo (2010)The inhibitory effects of a standarized apple peel polyphenol-rich extract (APPE) against Helicobacter pylori infection and vacuolating bacterial toxin (VacA) induced vacuolation were investigated. Apple peel polyphenols ...
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Pastene, Edgar; Speisky Cosoy, Hernán; Troncoso, Miriam; Alarcón, Julio; Figueroa, Guillermo (2009)In the present work, the in vitro effect of a standardized extract of apple peel APPE (60% of total polyphenols; 58% of flavonoids; 30% of flavan-3-ols and procyanidins) was evaluated with regard to the viability of ...
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Garrido, Gabino; González, Marisela Valdés; Valdés, Xavier Garrido; Vasallo, Antonio; Suárez, Bárbara B.Garrido; Delporte, Carla; Silveira, Damaris; De Chaves, Douglas S.A.; Pastene, Edgar; Spegazzini, Etile; Chemat, Farid; Castro, Fidel O.; Do Nascimento, Guilherme (Academic Association of Pharmaceutical Sciences from Antofagasta (ASOCIFA), 2017)
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Fuentes, Jocelyn; Arias Santé, M. Fernanda; Atala Riffo, Elías; Pastene, Edgar; Kogan Bocian, Marcelo; Speisky Cosoy, Hernán (Elsevier, 2020)The occurrence of the quercetin oxidation metabolite 2-(3,4-dihydroxybenzoyl)-2,4,6-trihydroxy-3(2H)-benzofuranone (BZF), whose antioxidant potency is notably higher than the antioxidant potency of quercetin, was investigated ...
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Andrade, Víctor; Cortés, Nicole; Pastor, Gabriela; González, Andrea; Ramos Escobar, Nicolás; Pastene, Edgar; Rojo, Leonel E.; Maccioni Baraona, Ricardo (IOS Press, 2020)Background: Alzheimer's disease (AD) is a multifactorial disease, that involves neuroinflammatory processes in which microglial cells respond to "damage signals". The latter includes oligomeric tau, iron, oxidative free ...
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Wong, Ximena; Madrid Silva, Ana; Tralma, Karina; Castillo, Romina; Carrasco Pozo, Catalina; Navarrete Wallace, Paola; Beltrán Muñoz, Caroll; Pastene, Edgar; Gotteland, Martin (Elsevier Science, 2016-10)The intestinal absorption of bacterial lipopolysaccharide (LPS) and dietary fat has been implicated in the development of metabolic endotoxemia. This study first compared the ability of polyphenol extracts from grape, ...
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Andriamihaja, Mireille; Lan, Annaig; Beaumont, Martin; Grauso, Marta; Gotteland, Martin; Pastene, Edgar; Cires, María José; Carrasco Pozo, Catalina; Tome, Daniel; Blachier, Francois (Springer, 2018-06)Hydrogen sulfide (H2S), a metabolic end product synthesized by the microbiota from l-cysteine, has been shown to act at low micromolar concentration as a mineral oxidative substrate in colonocytes while acting as an inhibitor ...
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Fuentes, Jocelyn; Atala, Elías; Pastene, Edgar; Carrasco Pozo, Catalina; Speisky Cosoy, Hernán (American Chemical Society, 2017)Quercetin oxidation is generally believed to ultimately result in the loss of its antioxidant properties. To test this assertion, quercetin oxidation was induced, and after each of its major metabolites was identified and ...