Browsing by Author "93d6c60a-3d6d-49b8-9b62-85cf8d36d371"

Now showing items 1-3 of 3

    • Genotoxic stress triggers the activation of IRE1 alpha-dependent RNA decay to modulate the DNA damage response 
      Dufey, Estefanie; Bravo San Pedro, José; Eggers Aracena, Cristián; González Quiroz, Matías; Urra Zúñiga, Hery; Sagredo Campos, Alfredo; Sepúlveda Alvarado, Denisse; Pihán Najle, Philippe; Carreras Sureda, Armando; Hazari, Younis; Sagredo, Eduardo A.; Gutiérrez, Daniela; Valls, Cristian; Papaioannou, Alexandra; Acosta Alvear, Diego; Campos, Gisela; Domingos, Pedro M.; Pedeux, Rémy; Chevet, Eric; Álvarez, Alejandra R.; Godoy, Patricio; Walter, Peter; Glavic Maurer, Álvaro; Kroemer, Guido; Hetz Flores, Claudio (Nature, 2020)
      The molecular connections between homeostatic systems that maintain both genome integrity and proteostasis are poorly understood. Here we identify the selective activation of the unfolded protein response transducer IRE1 ...
    • Gold Nanoparticles Mediate Improved Detection of beta-amyloid Aggregates by Fluorescence 
      Jara Guajardo, Pedro; Cabrera, Pablo; Celis, Freddy; Soler Jauma, Mónica; Berlanga Mora, Isadora; Parra Muñoz, Nicole; Acosta, Gerardo; Albericio, Fernando; Guzmán, Fanny; Campos, Marcelo; Álvarez, Alejandra; Morales Zavala, Francisco; Kogan, Marcelo J. (MDPI, 2020)
      The early detection of the amyloid beta peptide aggregates involved in Alzheimer's disease is crucial to test new potential treatments. In this research, we improved the detection of amyloid beta peptide aggregates in vitro ...
    • Peptide multifunctionalized gold nanorods decrease toxicity of beta-amyloid peptide in a Caenorhabditis ... 
      Morales Zavala, Francisco; Arriagada, Hector; Hassan, Natalia; Velasco, Carolina; Riveros Salvatierra, Ana; Álvarez, Alejandra R.; Minniti, Alicia N.; Rojas Silva, Ximena; Munoz, Luis L.; Vásquez Salfate, Rodrigo; Rodríguez, Katherine; Sánchez Navarro, Macarena; Giralt, Ernest; Araya, Eyleen; Aldunate, Rebeca; Kogan Bocian, Marcelo (Elsevier, 2017)
      The properties of nanometric materials make nanotechnology a promising platform for tackling problems of contemporary medicine. In this work, gold nanorods were synthetized and stabilized with polyethylene glycols and ...