Browsing by Author "945c53e4-d489-437b-b1fd-11ca8d96f096"

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    • Cyclin - dependent kinase 5 modulates the P2X2a receptor channel gating through phosphorylation of C - ... 
      Coddou, Claudio; Sandoval, Rodrigo; Castro, Patricio; Lazcano, Pablo; Hevia, María José; Rokic, Milos; Hall, Bradford; Terse, Anita; González Billault, Christian; Kulkarni, Ashok B.; Stojilkovic, Stanko S.; Utreras Puratich, Elías (Lippincott Williams & Wilkins, 2017)
      The purinergic P2X2 receptor (P2X2R) is an adenosine triphosphate-gated ion channel widely expressed in the nervous system. Here, we identified a putative cyclin-dependent kinase 5 (Cdk5) phosphorylation site in the full-size ...
    • Lipopolysaccharide inhibits the channel activity of the P2X7 receptor 
      Leiva Salcedo, Elías; Coddou, Claudio; Rodríguez, Felipe; Penna, Antonello; López, Ximena; Neira, Tanya; Fernández, Ricardo; Imarai, Mónica; Rios, Miguel; Escobar, Jorge; Montoya, Margarita; Huidobro Toro, Juan; Escobar, Alejandro; Acuña Castillo, Claudio (2011)
      The purinergic P2X7 receptor (P2X7R) plays an important role during the immune response, participating in several events such as cytokine release, apoptosis, and necrosis. The bacterial endotoxin lipopolysaccharide (LPS) ...