Browsing by Author "95db7617-1b8f-4914-90c2-43915e44d86a"

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    • GDF-11 prevents cardiomyocyte hypertrophy by maintaining the sarcoplasmic reticulum-mitochondria communication 
      Garrido-Moreno, Valeria; Díaz Vegas, Alexis; López Crisosto, Camila; Troncoso, Mayarling Francisca; Navarro Márquez, Mario F.; García Nannig, Lorena; Estrada, Manuel; Cifuentes, Mariana; Lavandero González, Sergio (Academic Press, 2019)
      Growth differentiation factor 11 (GDF11) is a novel factor with controversial effects on cardiac hypertrophy both in vivo and in vitro. Although recent evidence has corroborated that GDF11 prevents the development of cardiac ...
    • GDF11 Modulates Ca2+-Dependent Smad2/3 signaling to prevent cardiomyocyte hypertrophy 
      Durán, Javier; Troncoso, Mayarling Francisca; Lagos, Daniel; Ramos, Sebastian; Marin, Gabriel; Estrada, Manuel (MDPI, 2018-05)
      Growth differentiation factor 11 (GDF11), a member of the transforming growth factor- family, has been shown to act as a negative regulator in cardiac hypertrophy. Ca2+ signaling modulates cardiomyocyte growth; however, ...