Browsing by Author "97680b8b-f84b-4c22-bf0a-f191c2676508"

Now showing items 1-6 of 6

    • Beta2-adrenergic receptor regulates cardiac fibroblast autophagy and collagen degradation 
      Aránguiz Urroz, Pablo Daniel; Canales, Jimena; Copaja, Miguel; Troncoso, Rodrigo; Vicencio Bustamante, José Miguel; Carrillo, Constanza; Lara Peñaloza, Hernán; Lavandero González, Sergio; Díaz Araya, Guillermo (2011)
      Autophagy is a physiological degradative process key to cell survival during nutrient deprivation, cell differentiation and development. It plays a major role in the turnover of damaged macromolecules and organelles, and ...
    • Helicobacter pylori -induced inflammation and epigenetic changes during gastric carcinogenesis 
      Valenzuela, Manuel A.; Canales, Jimena; Corvalán, Alejandro H.; Quest, Andrew F. G. (WJG Press, 2015)
      © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. The sequence of events associated with the development of gastric cancer has been described as "the gastric precancerous cascade". ...
    • Helicobacter pylori Induced Phosphatidylinositol-3-OH Kinase/mTOR activation increases hypoxia inducible ... 
      Canales, Jimena; Valenzuela, Manuel; Bravo, Jimena; Cerda Opazo, Paulina; Jorquera, Carla; Toledo, Héctor; Bravo, Denisse; Quest, Andrew F. G. (Frontiers Media S.A., 2017)
      © 2017 Canales, Valenzuela, Bravo, Cerda-Opazo, Jorquera, Toledo, Bravo and Quest. Helicobacter pylori (H. pylori) is a human gastric pathogen that has been linked to the development of several gastric pathologies, such ...
    • K+ Channel Tetramerization Domain 5 (KCTD5) Protein Regulates Cell Migration, Focal Adhesion Dynamics and ... 
      Canales, Jimena; Cruz, Pablo; Villacura Díaz, Nicolás Esteban; Riquelme, Denise; Leiva Salcedo, Elias; Cerda Arancibia, Óscar (MDPI, 2020)
      Cell migration is critical for several physiological and pathophysiological processes. It depends on the coordinated action of kinases, phosphatases, Rho-GTPases proteins, and Ca2+ signaling. Interestingly, ubiquitination ...
    • KCTD5 and ubiquitin proteasome signaling are required for Helicobacter pylori adherence 
      Alvarez, Alhejandra; Uribe, Felipe; Canales, Jimena; Romero, Cristóbal; Soza, Andrea; Peña, María A.; Antonelli Anativia, Juan; Almarza, Oscar; Cerda Arancibia, Óscar; Toledo Araya, Héctor (Frontiers Media SA, 2017)
      In order to establish infection, bacterial pathogens modulate host cellular processes by using virulence factors, which are delivered from the bacteria to the host cell leading to cellular reprogramming. In this context, ...
    • Simvastatin induces apoptosis by a Rho-dependent mechanism in cultured cardiac fibroblasts and myofibroblasts 
      Copaja, Miguel; Venegas, Daniel; Aránguiz, Pablo; Canales, Jimena; Vivar, Raúl; Catalán, Mabel; Olmedo, Ivonne; Rodríguez, Andrea E.; Chiong Lay, Mario; Leyton Campos, Lisette; Lavandero González, Sergio; Díaz Araya, Guillermo (2011)
      Several clinical trials have shown the beneficial effects of statins in the prevention of coronary heart disease. Additionally, statins promote apoptosis in vascular smooth muscle cells, in renal tubular epithelial cells ...