Browsing by Author "9dfacfcc-ed70-40ee-8a32-43d46ef8faab"

Now showing items 1-4 of 4

    • A short hairpin RNA-based adjuvant targeting NF-kappa B repressor I kappa B alpha promotes migration of ... 
      Gálvez Cancino, Felipe; Roco, Jonathan; Rojas Colonelli, Nicole; Flores, Camila; Murgas, Paola; Cruz Gómez, Sebastián; Oyarce, Cesar; Varas Godoy, Manuel; Sauma Mahaluf, Daniela; Lladser, Álvaro (Elsevier, 2017)
      DNA vaccination is an attractive approach to elicit tumor-specific cytotoxic CD8(+) T lymphocytes (CTL), which can mediate protective immunity against tumors. To initiate CTL responses, antigen-encoding plasmids employed ...
    • Aggregatibacter actinomycetemcomitans Induces Autophagy in Human Junctional Epithelium Keratinocytes 
      Vicencio, Emiliano; Cordero, Esteban M.; Cortés, Bastián I.; Palominos, Sebastián; Parra, Pedro; Mella, Tania; Henrríquez, Constanza; Salazar, Nelda; Monasterio Ocares, Gustavo; Cafferata, Emilio A.; Murgas, Paola; Vernal Astudillo, Rolando; Cortez, Cristian (MDPI, 2020)
      The adverse environmental conditions found in the periodontium during periodontitis pathogenesis stimulate local autophagy responses, mainly due to a continuous inflammatory response against the dysbiotic subgingival ...
    • Cancer cells with defective oxidative phosphorylation require endoplasmic reticulum–to–mitochondria Ca2+ ... 
      Cárdenas, César; Lovy, Alenka; Silva Pavéz, Eduardo; Urra Faúndez, Félix; Mizzoni, Craig; Ahumada Castro, Ulises; Bustos, Galdo; Jaña, Fabián; Cruz, Pablo; Farías, Paula; Mendoza, Elizabeth; Huerta, Hernán; Murgas, Paola; Hunter, Martín; Ríos, Melany; Cerda Arancibia, Oscar; Georgakoudi, Irene; Zakarian, Armen; Molgó, Jordi; Foskett, James Kevin (AAAS. American Association for the Advancement of Science, 2020)
      Spontaneous Ca2+ signaling from the InsP(3)R intracellular Ca2+ release channel to mitochondria is essential for optimal oxidative phosphorylation (OXPHOS) and ATP production. In cells with defective OXPHOS, reductive ...
    • Immunotherapeutic potential of mollusk hemocyanins in combination with human vaccine adjuvants in murine ... 
      Román, Juan José Mora; Del Campo, Miguel; Villar, Javiera; Paolini, Francesca; Curzio, Gianfranca; Venuti, Aldo; Jara, Lilian; Ferreira, Jorge; Murgas, Paola; Lladser, Alvaro; Manubens, Augusto; Becker, María Inés (Hindawi Limited, 2019)
      Mollusk hemocyanins have been used for decades in immunological and clinical applications as natural, nontoxic, nonpathogenic, and nonspecific immunostimulants for the treatment of superficial bladder cancer, as ...