Browsing by Author "XX591534"

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    • Crosslinking and mass spectrometry suggest that the isolated NTD domain dimer of Moloney murine leukemia ... 
      Henríquez, Daniel R.; Zhao, Caifeng; Zheng, Haiyan; Arbildua, José J.; Acevedo Acevedo, Mónica; Roth, Monica J.; León Decap, Oscar (2013)
      Background: Retroviral integrases (INs) catalyze the integration of viral DNA in the chromosomal DNA of the infected cell. This reaction requires the multimerization of IN to coordinate a nucleophilic attack of the 3’ ...
    • Role of BK human polyomavirus in cancer 
      Levican, Jorge; Acevedo Acevedo, Mónica; León Decap, Oscar; Gaggero Brillouet, Aldo; Aguayo González, Francisco (Biomed Central, 2018)
      Human polyomaviruses (HPyV), which are small DNA viruses classified into the polyomaviridae family, are widely distributed in human populations. Thirteen distinct HPyVs have been described to date. Some of these viruses ...
    • Role of the 207–218 peptide region of Moloney murine leukemia virus integrase in enzyme catalysis 
      Acevedo Acevedo, Mónica; Arbildua, José J.; Monasterio Opazo, Octavio; Toledo Araya, Héctor; León Decap, Oscar (ELSEVIER, 2010)
      X-ray diffraction data on a few retroviral integrases show a flexible loop near the active site. By sequence alignment, the peptide region 207–218 of Mo-MLV IN appears to correspond to this flexible loop. In this study, ...