Browsing by Author "XX593147"

Now showing items 1-4 of 4

    • Bioinformatic survey for new physiological substrates of Cyclin-dependent kinase 5 
      Bórquez Muñoz, Daniel; Olmos, Cristina; Álvarez, Sebastián; Genova, Alex Di; Maass Sepúlveda, Alejandro; González Billault, Christian (Elsevier, 2013)
      Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase predominantly active in the nervous system where it regulates several processes such as neuronal migration, cytoskeletal dynamics, axonal ...
    • Dissecting the role of redox signaling in neuronal development 
      Bórquez Muñoz, Daniel; Urrutia, Pamela J.; Wilson, Carlos; Van Zundert, Brigitte; Núñez González, Marco; González Billault, Christian (Wiley-Blackwell, 2016)
      The generation of abnormally high levels of reactive oxygen species (ROS) is linked to cellular dysfunction, including neuronal toxicity and neurodegeneration. However, physiological ROS production modulates redox-sensitive ...
    • Regulation of cell polarity by controlled proteolytic systems 
      Bórquez Muñoz, Daniel; González Billault, Christian (SOC BIOLGIA CHILE, 2011)
      Epithelial and neuronal cells are highly asymmetric, with discrete regions responsible for different roles that underlie the generation of specific compartments within cells that are distinct in biochemical composition, ...
    • Searching for Novel Cdk5 Substrates in Brain by Comparative Phosphoproteomics of Wild Type and Cdk5 -/- Mice 
      Contreras Vallejos, Erick; Utreras Puratich, Elías; Bórquez Muñoz, Daniel; Prochazkova, Michaela; Terse, Anita; Jaffe, Howard; Toledo, Andrea; Arruti, Cristina; Pant, Harish C.; Kulkarni, Ashok B.; González Billault, Christian (2014)
      Protein phosphorylation is the most common post-translational modification that regulates several pivotal functions in cells. Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase which is mostly ...