Browsing by Author "XX596574"
Now showing items 1-14 of 14
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Aguirre, Verónica; Alvo Abodovsky, Miriam; Ardiles, Leopoldo; Carpio, J. Daniel; Foster, Carolina; Goecke Sariego, Irmgadt; Jalil, Roberto; Massardo, Loreto; Palma, Sergio; Roessler, Emilio; Wurgaft, Andrés (Sociedad Medica de Santiago, 2015)© 2015, Sociedad Medica de Santiago. All rights reserved. Renal involvement affects over one half of patients with Systemic Lupus Erythematosus increasing their mortality and morbidity, including chronic renal disease and ...
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Aguirre, Verónica; Alvo Abodovsky, Miriam; Ardiles, Leopoldo; Fierro, Alberto; Goecke Sariego, Irmgadt; Irureta Goyena, Mirentxu; Jalil, Roberto; Massardo, Loreto; Méndez, Gonzalo P.; Palma, Sergio; Roessler, Emilio; Silva, Francisco; Wurgaft, Andrés (Sociedad Médica de Santiago, 2018-02)Renal involvement is a frequent complication in antineutrophil cytoplasmic antibodies (ANCA)associated vasculitides, adding morbidity and mortality, such as chronic kidney disease and the need for renal replacement therapy. ...
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Urzúa Salinas, Cristhian; Velásquez Rojas, Víctor; Sabat Opazo, Pedro; Berger, Osvaldo; Ramírez, Sebastián; Goecke Sariego, Irmgadt; Vásquez, Darío H.; Gatica, Héctor; Guerrero, Julia (Wiley-Blackwell, 2015)Purpose: To evaluate clinical outcomes of first-line immunomodulatory therapy (IMT) and prednisone alone or late IMT in Vogt-Koyanagi-Harada disease. Methods: Retrospective cohort study of 152 patients with ...
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Goecke Sariego, Irmgadt; Bonilla, Silvia; Marusic, Elisa; Alvo Abodovsky, Miriam (Blackwell Publishing Inc., 1991)Translocation of potassium to the intracellular compartment is impaired in advanced chronic renal failure. The purpose of this study was to evaluate the role of endogenous insulin in the disposal of an oral potassium load ...
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Urzúa Salinas, Cristhian; Guerrero, Julia; Gatica, Hector; Velasquez, Victor; Goecke Sariego, Irmgadt (Association for Research in Vision and Ophthalmology Inc., 2017)© 2017 The Authors. PURPOSE. This study is aimed to investigate the role of glucocorticoid receptor (GR) isoforms in peripheral blood mononuclear cells (PBMC) as biomarkers of glucocorticoid (GC) resistance and to validate ...
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Urzúa Salinas, Cristhian; Si, Han; Liu, Baoying; Lait, Philippa; Lee, Richard; Goecke Sariego, Irmgadt; Nussenblatt, Robert (Association for Research in Vision and Ophthalmology, 2015)Purpose: Glucocorticoids (GC) have been the mainstay therapy for autoimmue uveitis for decades, but up to one third of patients are unable to achieve disease control at tolerable GC doses, developing vision-threatening ...
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Karsulovic Cvitanich, Claudio; Tempio, Fabián; López Nitsche, Mercedes; Guerrero Peralta, Julia; Goecke Sariego, Irmgadt (Dove Medical Press, 2021)Introduction: CD14 (monocyte differentiation antigen, LPS binding protein - endotoxin receptor) and CD16 (FcyRIII, Low-affinity receptor for IgG) define three subpopulations of circulating monocytes with different inflammatory ...
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Wurmann Kiblisky, Pamela; Sabugo Siraqyan, María Francisca; Elgueta, Fabián; Mac-Namara, Macarena; Vergara González, Karen; Vargas, Daniela; Molina Cousiño, María Luisa; Díaz Patino, Juan Carlos; Gatica Rossi, Héctor; Goecke Sariego, Irmgadt (Mattioli 1885, 2020)Objective: To describe the clinical and serological patients characteristics with Microscopic Polyangiitis (MPA) and Interstitial lung disease (ILD). Methods: Of all the patients with AAV diagnosed between 2007-2017 at the ...
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Mancilla Vergara, Edna; Galindo Díaz, Mario; Fertilio, Bárbara; Herrera Moore, Mario; Salas, Karime; Gatica Rossi, Héctor; Goecke Sariego, Irmgadt (2007)Longitudinal bone growth occurs by a process called endochondral ossification that includes chondrocyte proliferation, differentiation, and apoptosis. Recent studies have suggested a regulatory role for intracellular Ca-2 ...
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Molina Cousiño, María Luisa; Guerrero Peralta, Julia; Cidlowski, John A.; Gatica Rossi, Héctor; Goecke Sariego, Irmgadt (Biomed Central Ltd., 2017)Background: This study was aimed to evaluate the effect of LPS in glucocorticoid receptor (GR) isoforms expression on different cell lines and PBMC from healthy donors in vitro and glucocorticoid sensitivity of PBMC in ...
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Karsulovic Cvitanich, Claudio; López Nitsche, Mercedes; Tempio Sepúlveda, Fabián; Guerrero Peralta, Julia; Goecke Sariego, Irmgadt (Elsevier, 2020)
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Elgueta Segura, Leticia; Ricci Larrea, Lara; Vargas, D.; Wurmann Kiblisky, Pamela; Goecke Sariego, Irmgadt (BMJ, 2017)
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Bofill, Pilar; Goecke Sariego, Irmgadt; Bonilla, Silvia; Alvo Abodovsky, Miriam; Marusic, Elisa (Nature Publishing Group, 1994)Chronic renal failure in the rat is associated with an impaired extrarenal potassium handling, whereas a renal adaptive mechanism of the remaining nephrons has been described. To understand the molecular basis of potassium ...
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Radominski, Sebastiao; Cardiel, Mario; Citera, Gustavo; Goecke Sariego, Irmgadt; Jaller, Juan José; Vannucci Lomonte, Andrea Barranjard; Miranda, Pedro; Vélez, Patricia; Xibille, Daniel; Kwok, Kenneth; Rojo, Ricardo; García, Erika Gabriela (Elsevier, 2017)Objective: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). We assessed tofacitinib efficacy and safety in the Latin American (LA) subpopulation of global Phase 3 and long-term ...