Now showing items 1-18 of 18

    • Dünner Moreno, Natalia Hilda (Universidad de Chile, 2011)
      La insuficiencia renal crónica (IRC) induce una serie de alteraciones metabólicas en el músculo esquelético, debilidad muscular y disminución de la resistencia al ejercicio. Interleuquina-6 (IL-6) es una citoquina que se ...
    • Michea Acevedo, Luis; Alvo Abodovsky, Miriam; Morales, Helia; Brito, Julio; Peters, Gabriela; Marusic, Elisa (1997)
      Background: Sodium and potassium ions are involved in the regulation of blood pressure and the genesis of hypertension. Aim: To assess internal potassium balance, as a measure of sodium pump activity, in subjects with ...
    • Araos, Patricio; Prado, Carolina; Lozano, Mauricio; Figueroa, Stefanny; Espinoza, Alexandra; Berger, Thorsten; Mak, Tak W.; Jaisser, Frédéric; Pacheco, Rodrigo; Michea Acevedo, Luis; Amador, Cristián A. (Lippincott Williams and Wilkins, 2019)
      Background:Adaptive immunity is crucial in cardiovascular and renal inflammation/fibrosis upon hyperactivation of mineralocorticoid receptor. We have previously demonstrated that dendritic cells can respond to mineralocorticoid ...
    • Defilippi Cafri, Carlos; Madrid Silva, Ana; Salas, Karime; Michea Acevedo, Luis; Lagos Wilson, Néstor (2000-04)
      Studies have shown a promoting effect of food on small intestinal absorption. Casein hydrolysate seems be more effective in increasing of D-xylose absorption in dogs than the whole protein and lactulose. The purpose this ...
    • Bonilla, Silvia; Goecke Sariego, Irmgadt; Bozzo, Salvador; Alvo Abodovsky, Miriam; Michea Acevedo, Luis; Marusic, Elisa (1991)
      Previous studies have suggested that an alteration in the expression of the NaK-ATPase of muscle may be an important determinant of enhanced insulin sensitivity in chronic renal failure. Therefore, in the present studies ...
    • Michea Acevedo, Luis; Delpiano Barriga, Ana María; Hitschfeld, C.; Lobos González, Lorena; Lavandero González, Sergio; Marusic, Elisa (ENDOCRINE SOC, 2005-03)
      There is increasing evidence for rapid nongenomic effects of aldosterone. Aldosterone has been demonstrated to alter intracellular pH and calcium in isolated cells. However, few studies have correlated these effects with ...
    • Toro, Luis; Barrientos, Víctor; León, Pablo; Rojas, Macarena; González, Magdalena; González Ibáñez, Álvaro; Illanes, Sebastián E.; Sugikawa, Keigo; Abarzu, Néstor; Bascuñán, César; Arcos, Katherine; Fuentealba, Carlos; Tong, Ana María; Elorza, Alvaro A.; Pinto, María Eugenia; Alzamora Miranda, Rodrigo; Romero, Carlos; Michea Acevedo, Luis (Elsevier, 2018)
      It is accepted that osteoblasts/osteocytes are the major source for circulating fibroblast growth factor 23 (FGF23). However, erythropoietic cells of bone marrow also express FGF23. The modulation of FGF23 expression in ...
    • Arriagada, Alejandro A.; Albornoz, Eduardo; Opazo, María Cecilia; Becerra, Álvaro; Vidal, Gonzalo; Fardella, Carlos; Michea Acevedo, Luis; Carrasco, Nancy; Simón, Felipe; Elorza, Álvaro A.; Bueno, Susan M.; Kalergis, Alexis M.; Riedel, Claudia A. (Endocrine Society, 2015)
      Na+/I- symporter (NIS) mediates iodide (I-) uptake in the thyroid gland, the first and rate-limiting step in the biosynthesis of the thyroid hormones. The expression and function of NIS in thyroid cells is mainly regulated ...
    • Tapia Castillo, Alejandra; Carvajal, Cristian; Campino, Carmen; Hill, Caroline; Allende, Fidel; Vecchiola, Andrea; Carrasco, Carmen; Bancalari, Rodrigo; Valdivia, Carolina; Lagos, Carlos; Martínez Aguayo, Alejandro; García, Hernán; Aglony, Marlene; Baudrand, René; Kalergis, Alexis; Michea Acevedo, Luis; Riedel, Claudia; Fardella, Carlos (Oxford University Press, 2015)
      BACKGROUND Rac1 upregulation has been implicated in salt-sensitive hypertension as a modulator of mineralocorticoid receptor (MR) activity. Rac1 could affect the expression of oxidative stress markers, such as ...
    • Romero Patiño, Carlos; Michea Acevedo, Luis; Illanes Diez, Sergio; Serra, R.; Pino, K.; Figueroa‐Diesel, H.; Soothill, P. W; Parra Cordero, Mauro (Wiley InterScience, 2009-10-08)
      Objective To determine if maternal plasma ffDNA is increased early in pregnancies which subsequently develop preeclampsia (PE) and intrauterine growth restriction (IUGR). Methods Blood was obtained at 11–14 weeks and ...
    • Chiong Lay, Mario; Morales, Pablo Esteban; Torres, Gloria; Gutiérrez, Tómas; García Nannig, Lorena; Ibacache, Mauricio; Michea Acevedo, Luis (Hans Huber, 2013)
      Diff erentiation of vascular smooth muscle cells (VSMC) is an essential process of vascular development. VSMC have biosynthetic, proliferative, and contractile roles in the vessel wall. Alterations in the diff erentiated ...
    • Pasten, Consuelo; Alvarado, Cristóbal; Rocco, Jocelyn; Contreras, Luis; Aracena, Paula; Liberona, Jéssica; Suazo, Cristian; Michea Acevedo, Luis; Irarrázabal, Carlos E. (American Physiological Society, 2019)
      Copyright © 2019 the American Physiological Society.—On renal ischemia-reperfusion (I/R) injury, recruitment of neutrophils during the inflammatory process promotes local generation of oxygen and nitrogen reactive species, ...
    • Michea Acevedo, Luis; Fuente Vera, Milton de la; Lagos Wilson, Néstor (1994)
      The vertebrate lens behaves like a syncytium, and it is formed mainly by cells called lens fibers. Between the fibers are extensive networks of membrane junctions. The major intrinsic protein (MIP) constitutes about ...
    • Rojas, Macarena; Díaz Moreno, Pablo; León, Pablo; González, Alexis A.; González, Magdalena; Barrientos, Víctor; Pestov, Nikolay B.; Alzamora Miranda, Rodrigo; Michea Acevedo, Luis (Taylor & Francis, 2017)
      Renal sodium reabsorption depends on the activity of the Na+,K+-ATPase / heterodimer. Four ((1-4)) and 3 ((1-3)) subunit isoforms have been described. It is accepted that renal tubule cells express (1)/(1) dimers. Aldosterone ...
    • Hevia, Daniel; Araos, Patricio; Prado, Carolina; Fuentes Luppichini, Eugenia; Rojas, Macarena; Alzamora Miranda, Rodrigo; Cifuentes Araneda, Flavia; González, Alexis A.; Amador, Cristian A.; Pacheco, Rodrigo; Michea Acevedo, Luis (Lippincott Williams & Wilkins, 2018)
      Increasing evidence shows that antigen-presenting cells (APCs) are involved in the development of inflammation associated to hypertension. However, the potential role of APCs in the modulation of renal sodium transport has ...
    • Tittarelli, A.; Guerrero, I.; Tempio, F.; Gleisner, M. A.; Avalos, I.; Sabanegh, S.; Ortiz, C.; Michea Acevedo, Luis; López, M. N.; Mendoza Naranjo, A.; Salazar Onfray, Flavio (Cancer Research UK, 2015)
      Background: Alterations in connexin 43 (Cx43) expression and/or gap junction (GJ)-mediated intercellular communication are implicated in cancer pathogenesis. Herein, we have investigated the role of Cx43 in melanoma cell ...
    • González, G.; Baudrand, R.; Sepúlveda, M. F.; Vucetich, N.; Guarda, F. J.; Villanueva, P.; Contreras, O.; Villa, A.; Salech Morales, Felipe; Toro Cabrera, Luis; Michea Acevedo, Luis; Florenzano, P. (Springer, 2017)
      The majority of tumor-induced osteomalacia cases have been reported in the Northern Hemisphere and Asia. In this first series of South American patients, we show that the clinical presentation and sensitivity of plasmatic ...
    • Tarjus, Antoine; Amador, Cristian; Michea Acevedo, Luis; Jaisser, Frédéric (Elsevier, 2015)
      The mineralocorticoid receptor (MR) is a major regulator of blood pressure by modulating sodium balance and blood volume in the distal nephron. The discovery of MR expression in both endothelial and vascular smooth ...