Browsing by Author "XX633236"

Now showing items 1-6 of 6

    • ATP signaling in skeletal muscle: from fiber plasticity to regulation of metabolism 
      Casas Atala, Mariana; Buvinic Radic, Sonja; Jaimovich Pérez, Enrique (2014)
      Tetanic electrical stimulation releases adenosine triphosphate (ATP) from muscle fibers through pannexin-1 channels in a frequency-dependent manner; extracellular ATP activates signals that ultimately regulate gene ...
    • Cav1.1 controls frequency-dependent events regulating adult skeletal muscle plasticity 
      Jorquera, Gonzalo; Altamirano, Francisco; Contreras Ferrat, Ariel Eduardo; Almarza, Gonzalo; Buvinic Radic, Sonja; Jacquemond, Vincent; Jaimovich Pérez, Enrique; Casas Atala, Mariana (The Company of Biologists, 2013)
      An important pending question in neuromuscular biology is how skeletal muscle cells decipher the stimulation pattern coming from motoneurons to define their phenotype as slow or fast twitch muscle fibers. We have previously ...
    • Characterization of a multiprotein complex involved in excitation-transcription coupling of skeletal muscle 
      Arias Calderón, Manuel; Almarza, Gonzalo; Díaz Vegas, Alexis; Contreras Ferrat, Ariel Eduardo; Valladares Ide, Denisse; Casas Atala, Mariana; Toledo Araya, Héctor; Jaimovich Pérez, Enrique; Buvinic Radic, Sonja (Biomed Central, 2016)
      Background: Electrical activity regulates the expression of skeletal muscle genes by a process known as “ excitation-transcription” (E-T) coupling. We have demonstrated that release of adenosine 5′-triphosphate (ATP) ...
    • Early molecular response and microanatomical changes in the masseter muscle and mandibular head after ... 
      Balanta Melo, Julián; Toro Ibacache, Viviana; Torres Quintana, M. A.; Kupczik, Kornelius; Vega, Carolina; Morales, Camilo; Hernández Moya, Nadia; Arias Calderón, Manuel; Beato, Carolina; Buvinic Radic, Sonja (Elsevier, 2018)
      Background: Masseter muscle paralysis induced by botulinum toxin type A (BoNTA) evokes subchondral bone loss in mandibular heads of adult rats and growing mice after 4 weeks. However, the primary cellular and molecular ...
    • Electrical stimulation induces IL-6 in skeletal muscle through extracellular ATP by activating Ca2 signals ... 
      Bustamante, Mario; Fernández Verdejo, Rodrigo; Jaimovich Pérez, Enrique; Buvinic Radic, Sonja (American Physiological Society, 2014)
      S. Electrical stimulation induces IL-6 in skeletal muscle through extracellular ATP by activating Ca2 signals and an IL-6 autocrine loop. Am J Physiol Endocrinol Metab 306: E869 –E882, 2014. First published February ...
    • ROS Production via P2Y(1)-PKC-NOX2 Is Triggered by Extracellular ATP after Electrical Stimulation of Skeletal ... 
      Díaz Vegas, Alexis; Campos, Cristian A.; Contreras Ferrat, Ariel Eduardo; Casas Atala, Mariana; Buvinic Radic, Sonja; Jaimovich Pérez, Enrique; Espinosa Escalona, Alejandra (Public Library Science, 2015)
      During exercise, skeletal muscle produces reactive oxygen species (ROS) via NADPH oxidase (NOX2) while inducing cellular adaptations associated with contractile activity. The signals involved in this mechanism are still a ...