Browsing by Author "XX635526"
Now showing items 1-14 of 14
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Sánchez, Catherine; Mercado, Alejandro; Contreras, Héctor R.; Mendoza, Patricia; Cabezas Castillo, Juan; Acevedo, Cristian; Huidobro Alvarado, Christian; Castellón Vera, Enrique (WILEY-BLACKWELL, 2011-12)BACKGROUND. In several cancer types, expression of multidrug resistance (MDR) proteins has been associated with lack of chemotherapy response. In advanced prostate cancer (PCa) the use of chemotherapy is mainly palliative ...
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Sánchez, Catherine; Clementi, Marisa; Benítez, Dixan; Contreras, Héctor R.; Huidobro Alvarado, Christian; Castellón Vera, Enrique (WILEY-LISS, DIV JOHN WILEY & SONS INC, 2005-11-01)BACKGROUND. GnRH analogs have antiproliferative and/or apoptotic effects on prostate cancer cells. Also, neurotrophin receptors TrkA and p75 have been reported in normal prostate suggesting a role in the gland growth ...
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Sánchez, Catherine A.; Andahur, Eliana I.; Valenzuela, Rodrigo; Castellón Vera, Enrique; Fulla Ortiz, Juan; Ramos, Christian G.; Triviño, Juan C. (IMPACT JOURNALS LLC, 2015)The different prostate cancer (PCa) cell populations (bulk and cancer stem cells, CSCs) release exosomes that contain miRNAs that could modify the local or premetastatic niche. The analysis of the differential expression ...
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Poblete, Christian E.; Fulla, Juan; Gallardo, Marcela; Muñoz, Valentina; Castellón Vera, Enrique; Gallegos, Iván; Contreras Muñoz, Héctor (Oxford University Press, 2014)Prostate cancer (PC) is a leading male oncologic malignancy wideworld. During malignant transformation, normal epithelial cells undergo genetic and morphological changes known as epithelial-mesenchymal transition (EMT). ...
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Castellón Vera, Enrique; Valenzuela Matamala, Rubén; Cifuentes, F.; Contreras Muñoz, Héctor (Elsevier, 2015)
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Kato, Sumie; Abarzúa Catalán, Lorena; Trigo, César; Delpiano, Ana; Sanhueza, Cristóbal; García, Karen; Ibáñez, Carolina; Hormazábal, Katherine; Díaz, Daniela; Brañes, Jorge; Castellón Vera, Enrique; Bravo, Erasmo; Owen, Gareth; Cuello, Mauricio (Impact Journals LLC, 2015)The evidence linking obesity with ovarian cancer remains controversial. Leptin is expressed at higher levels in obese women and stimulates cell migration in other epithelial cancers. Here, we explored the clinical impact ...
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Castellón Vera, Enrique (Blackwell, 2019)
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Orellana Serradell, O.; Poblete, C. E.; Sánchez, C.; Castellón Vera, Enrique; Gallegos Méndez, Iván; Huidobro, C.; Llanos Silva, Miguel; Contreras, H. R. (2015)In the early stages, prostate cancer is androgendependent; therefore, medical castration has shown significant results during the initial stages of this pathology. Despite this early effect, advanced prostate cancer is ...
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Castellón Vera, Enrique; Valenzuela Báez, Rodrigo; Cifuentes, Federico; Thomson, Timothy; Contreras Muñoz, Héctor (Spandidos Publications Ltd., 2017)
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Farfán, Nancy; Orellana Serradell, Octavio; Herrera, Daniela; Chrzanowsky, Dominique; Cubillos, Paulina; Marín, Gabriel; García de Herreros, Antonio; Castellón Vera, Enrique; Contreras Muñóz, Héctor (Spandidos Publications, 2020)Zinc finger protein SNAI1 (SNAIL) and zinc finger protein SNAI2 (SLUG) transcription factors promote epithelial-mesenchymal transition, a process through which epithelial cells acquire a mesenchymal phenotype, increasing ...
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Osorio, Luis A.; Farfán, Nancy; Castellón Vera, Enrique; Contreras, Héctor R. (Spandidos, 2016)The incidence and mortality rates of prostate cancer (PCa) are increasing, and PCa is almost the second-leading cause of cancer-associated mortality in men. During tumor progression, epithelial cells decrease the number ...
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Contreras Muñoz, Héctor; Farfán, N.; Orellana Serradell, Octavio; Chrzanowsky Ampuero, Dominique; Castellón Vera, Enrique (Elsevier, 2015)
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Cifuentes, Federico; Valenzuela Pérez, Rodrigo; Contreras Muñoz, Héctor; Castellón Vera, Enrique (Spandidos, 2015)Metastatic prostate cancer (mPCa) is one of the most prevalent cancers in men worldwide. The main cause of death in these patients is androgen-resistant metastatic disease. Surgery of the primary tumor has been avoided ...
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Farfán, Nancy; Ocarez, Nallatt; Castellón Vera, Enrique; Mejía, Nilo; García de Herreros, Antonio; Contreras, Héctor R. (Nature, 2018)Syndecan 1 (SDC-1) is a cell surface proteoglycan with a significant role in cell adhesion, maintaining epithelial integrity. SDC1 expression is inversely related to aggressiveness in prostate cancer (PCa). During epithelial ...