Browsing by Author "XX639996"
Now showing items 1-13 of 13
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Astudillo Maya, Andrea; Karmelic Visinteiner, Daniel; Casas Atala, Bárbara; Otmakhov, Nikolai; Palma Alvarado, Verónica; Sanhueza Toha, María Magdalena (Wiley, 2020)CaMK2N1 and CaMK2N2 (also known as CaMKIIN alpha and beta) are endogenous inhibitors of calcium/calmodulin-dependent kinase II (CaMKII), an enzyme critical for memory and long-term potentiation (LTP), a form of synaptic ...
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Peña Villalobos, Isaac; Casanova Maldonado, Ignacio; Lois Silva, Pablo; Palma Alvarado, Verónica; Sabat Kirkwood, Pablo (Nature, 2020)In order to maintain the energy balance, animals often exhibit several physiological adjustments when subjected to a decrease in resource availability. Specifically, some rodents show increases in behavioral activity in ...
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Santander, Nicolás; Lizama, Carlos; Parga, María José; Quiroz, Alonso; Pérez, Druso; Echeverria, Guadalupe; Ulloa, Lorena; Palma Alvarado, Verónica; Rigotti, Attilio; Busso, Dolores (Nature Publishing Group, 2017)SR-BI is the main receptor for high density lipoproteins (HDL) and mediates the bidirectional transport of lipids, such as cholesterol and vitamin E, between these particles and cells. During early development, SR-BI is ...
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Casas, Bárbara S.; Adolphe, Christelle; Lois, Pablo; Navarrete Novoa, Nelson; Solis, Natalia; Bustamante, Eva; Gac Espinoza, Patricio; Cabane Toledo, Patricio; Gallegos Méndez, Iván; Wainwright, Brandon J.; Palma Alvarado, Verónica (Impact Journals Llc., 2017)Basal Cell Carcinoma (BCC) is one of the most diagnosed cancers worldwide. It develops due to an unrestrained Sonic Hedgehog (SHH) signaling activity in basal cells of the skin. Certain subtypes of BCC are more aggressive ...
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Casas, Bárbara S.; Vitória, Gabriela; do Costa, Marcelo N.; Madeiro da Costa, Rodrigo; Trindade, Pablo; Maciel, Renata; Navarrete Novoa, Nelson; Rehen, Stevens K.; Palma Alvarado, Verónica (Nature Publishing Group, 2018)Schizophrenia is a neurodevelopmental disease characterized by cerebral connectivity impairment and loss of gray matter. It was described in adult schizophrenia patients (SZP) that concentration of VEGFA, a master angiogenic ...
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Martínez, Constanza E.; Smith, Patricio C.; Palma Alvarado, Verónica (Frontiers Media, 2015)Platelet degranulation allows the release of a large amount of soluble mediators, is an essential step for wound healing initiation, and stimulates clotting, and angiogenesis. The latter process is one of the most critical ...
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Rapaciolii, Melina; Palma Alvarado, Verónica; Flores Carrasco, Vladimir (Frontiers Media, 2016)The central nervous system areas displaying the highest structural and functional complexity correspond to the so called cortices, i.e., concentric alternating neuronal and fibrous layers. Corticogenesis, i.e., the development ...
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Espinoza Giacomozzi, Natalie Andrea (Universidad de Chile, 2012)El desarrollo embrionario en vertebrados es coordinado por una red de señales y factores de crecimiento que comandan diferentes procesos celulares. Sonic Hedgehog (SHH), es un ligando considerado como un regulador maestro ...
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Martínez, Constanza E.; González, Sergio A.; Palma Alvarado, Verónica; Smith, Patricio C. (Amer Acad Periodontology, 2016)Background: Plasma-derived fractions have been used as an autologous source of growth factors; however, limited knowledge concerning their biologic effects has hampered their clinical application. In this study, the ...
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Botelho, João; Smith Paredes, Daniel; Soto Acuña, Sergio; Mpodozis Marín, Jorge; Palma Alvarado, Verónica; Vargas Milne, Alexander (Nature, 2015)Most birds have an opposable digit 1 (hallux) allowing the foot to grasp, which evolved from the non-opposable hallux of early theropod dinosaurs. An important morphological difference with early theropods is the twisting ...
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Reinchisi, Gisela; Parada, Margarita; Lois, Pablo; Oyanadel, Claudia; Shaughnessy, Ronan; Gonzalez, Alfonso; Palma Alvarado, Verónica (2013-09)Sonic Hedgehog (Shh/GLI) and EGFR signaling pathways modulate Neural Stem Cell (NSC) proliferation. How these signals cooperate is therefore critical for understanding normal brain development and function. Here we report ...
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Palma Alvarado, Verónica; Pitossi, Fernando; Rehen, Stevens; Touriño, Cristina; Velasco, Iván (Future Medicine, 2015)Stem cell research is attracting wide attention as a promising and fast-growing field in Latin America, as it is worldwide. Many countries in the region have defined Regenerative Medicine as a research priority and a ...
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Torres, Pedro; Díaz Jara, Jorge; Arce, Maximiliano; Silva, Patricio; Mendoza, Pablo; Lois, Pablo; Molina Berríos, Alfredo Enrique; Owen, Gareth I.; Palma Alvarado, Verónica; Torres Gómez, Vicente (Federation of American Societies for Experimental Biology, 2017)Saliva is a key factor that contributes to the high efficiency of wound healing in the oral mucosa. This is not only attributed to physical cues but also to the presence of specific peptides in the saliva, such as histatins. ...