Browsing by Author "XX676107"
Now showing items 1-20 of 26
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Andrade, David C.; Toledo, Camilo; Díaz, Hugo S.; Lucero, Claudia; Arce-Álvarez, Alexis; Oliveira, Luiz M.; Takakura, Ana C.; Moreira, Thiago S.; Schultz, Harold D.; Marcus, Noah J.; Alcayaga Urbina, Julio; Rio, Rodrigo Del (Portland Press Ltd, 2019)Activation of the sympathetic nervous system is a hallmark of heart failure (HF) and is positively correlated with disease progression. Catecholaminergic (C1) neurons located in the rostral ventrolateral medulla (RVLM) are ...
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Reyes, Edison Pablo; Alcayaga Urbina, Julio; Zapata, Patricio (ELSEVIER, 2006-08-30)We investigate possible interactions between acetylcholine (ACh)- and adenosine 5'-triphosphate (ATP)-induced responses of petrosal ganglion, where the perikarya of most sensory neurons of the glossopharyngeal nerve are ...
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Alcayaga, Carmen; Varas, Rodrigo; Valdés, Viviana; Cerpa, Verónica; Arroyo, Jorge; Iturriaga, Rodrigo; Alcayaga Urbina, Julio (ELSEVIER SCIENCE BV, 2007-02)Chemoreceptor (glomus) cells of the carotid body are synaptically connected to the sensory nerve endings of petrosal ganglion (PG) neurons. In response to natural stimuli, the glomus cells release transmitters,which ...
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Paredes Zúñiga, Susana; Trost, Nils; Paz, Javiera F. de la; Alcayaga Urbina, Julio; Allende Connelly, Miguel (Elsevier, 2019)Triadimefon (TDF) is a triazole fungicide extensively used in agriculture that has been found as a pollutant in numerous water sources. In mammals, it inhibits monoamine uptake through binding to the dopamine transporter, ...
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Rey, Sergio; Río, Rodrigo del; Alcayaga Urbina, Julio; Iturriaga, Rodrigo (BLACKWELL, 2004-10-15)The carotid body (CB) chemoreceptors may play an important role in the enhanced hypoxic ventilatory response induced by chronic intermittent hypoxia (CIH). We studied the effects of cyclic hypoxic episodes of short duration ...
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Alcayaga Urbina, Julio; Oyarce, María Paz; Iturriaga, Rodrigo (Federation Amer Soc Exp Biol, 2015)
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Alcayaga Urbina, Julio; Oyarce, María P.; Del Río, Rodrigo (Elsevier, 2016-10-15)Ventilation is peripherally controlled by afferent activity arising from the peripheral chemoreceptors. In the rat, chemosensory activity is conveyed to the central nervous system through axons of neurons located in the ...
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Soto Vera, Jorge Ignacio; Alcayaga Urbina, Julio; Sanhueza, Magdalena (Frontiers Research Foundation, 2017)© 2017 Vera, Alcayaga and Sanhueza. Neurons from many brain regions display intrinsic subthreshold theta-resonance, responding preferentially to theta-frequency oscillatory stimuli. Resonance may contribute to selective ...
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Retamal, Mauricio A.; Riquelme, Manuel A.; Stehberg, Jimmy; Alcayaga Urbina, Julio (Frontiers Media, 2017)In this review article, we summarize the current insight on the role of Connexin- and Pannexin-based channels as modulators of sensory neurons. The somas of sensory neurons are located in sensory ganglia (i.e., trigeminal ...
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Iturriaga, R.; Alcayaga Urbina, Julio; Zapata, P. (Blackwell Publishing Ltd, 1996)1. To examine the correlation between chemosensory response and dopamine release induced by hypoxic stimulation, we studied carotid bodies excised from anaesthetized cats. 2. The carotid bodies with their carotid (sinus) ...
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Iturriaga, Rodrigo; Alcayaga Urbina, Julio (ELSEVIER SCIENCE BV, 2007-01-12)Exposure to chronic intermittent hypoxia (CIH) for 4 days enhances the cat carotid body (CB) chemosensory responses to acute hypoxia. However, it is not known if CIH enhances the responses of the petrosal ganglion (PG) ...
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Iturriaga, Rodrigo; Varas, Rodrigo; Alcayaga Urbina, Julio (2007)The petrosal ganglion (PG) contains the somata of primary afferent neurons that innervate the chemoreceptor (glomus) cells in the carotid body (CB). The most accepted model of CB chemoreception states that natural stimuli ...
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Varas, Rodrigo; Valdés, Viviana; Iturriaga-Vásquez, Patricio; Cassels Niven, Bruce; Iturriaga, Rodrigo; Alcayaga Urbina, Julio (ELSEVIER, 2006-02-09)Petrosal ganglion neurons are depolarized and fire action potentials in response to acetylcholine and nicotine. However, little is known about the subtype(s) of nicotinic acetylcholine receptors involved, although alpha 4 ...
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Rey, Sergio; Río, Rodrigo del; Alcayaga Urbina, Julio; Iturriaga, Rodrigo (ELSEVIER SCIENCE BV, 2006-01-19)In response to hypoxia, chemoreceptor cells of the carotid body (CB) release transmitters, which acting on the petrosal ganglion (PG) neuron terminals, increase the chemoafferent discharge. Additionally, vasoactive ...
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Ortiz, Fernando C.; Del Rio, Rodrigo; Ebensperger Darrouy, Germán; Reyes Catalán, Víctor; Alcayaga Urbina, Julio; Varas, Rodrigo; Iturriaga, Rodrigo (Elsevier, 2013)Chronic intermittent hypoxia (CIH), the main feature of obstructive sleep apnea, enhances carotid body (CB) chemosensory responses to acute hypoxia. In spite of that, the primary molecular target of CIH in the CB remains ...
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Navarrete Opazo, Angela; Alcayaga Urbina, Julio; Testa, Denisse; Quinteros, Ana Luisa (Oxford Univ. Press Inc., 2016)There is a critical need for new therapeutic strategies to restore motor function in patients with spinal cord injuries (SCIs), without unwanted effects. Intermittent hypoxia (IH) induces plasticity in spared synaptic ...
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Ortíz, Fernando C.; Vergara Montecinos, Cecilia; Alcayaga Urbina, Julio (Springer, 2014)Copper plays a key role in aerobic cell physiology mainly related to mitochondrial metabolism. This element is also present at higher than basal levels in some central nuclei and indeed, current evidence support copper’s ...
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Río, Rodrigo del; Moya, Esteban A.; Koenig, Cecilia S.; Fujiwara, Kunio; Alcayaga Urbina, Julio; Iturriaga, Rodrigo (ELSEVIER, 2008-12-31)Histamine has been proposed to be an excitatory transmitter between the carotid body (CB) chemoreceptor (glomus) cells and petrosal ganglion (PG) neurons. The histamine biosynthetic pathway, its storage and release, as ...
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Iturriaga, Rodrigo; Alcayaga Urbina, Julio (ELSEVIER SCIENCE BV, 2004-12)The carotid body (CB) is the main arterial chemoreceptor. The most accepted model of arterial chemoreception postulates that carotid body glomus (type 1) cells are the primary receptors, which are synaptically connected ...
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Iturriaga, Rodrigo; Alcayaga Urbina, Julio (ELSEVIER, 2004-12)The carotid body (CB) is the main arterial chemoreceptor. The most accepted model of arterial chemoreception postulates that carotid body glomus (type 1) cells are the primary receptors, which are synaptically connected ...