Browsing by Author "XX676278"

Now showing items 1-7 of 7

    • Clinical parameters and biomarkers for anti-TNF treatment prognosis in rheumatoid arthritis patients 
      Cuchacovich Turteltaub, Miguel; Bueno, Daniel; Carvajal Gavilán, Rodrigo; Bravo, Nicolás; Aguillón Gutiérrez, Juan Carlos; Catalán Martina, Diego; Soto Sáez, Lilian (International League of Associations for Rheumatology (ILAR), 2014)
      Tumor necrosis factor (TNF) plays a pivotal role in the pathogenesis of rheumatoid arthritis (RA). This finding has led to the development of TNF blockers for RA treatment. However, response to these therapies is ...
    • Expression of steroid sulfated transporters and 3 beta-HSD activity in endometrium of women having polycystic ... 
      Plaza Parrochia, Francisca; Poblete, Cristian; Gabler Neale, Fernando; Carvajal Gavilán, Rodrigo; Romero Osses, Carmen; Valladares Boasi, Luis; Vega Blanco, María Margarita (Elsevier, 2015)
      Intracrinology mechanism involves the metabolism of steroids in peripheral tissues, such as DHEA, to molecules with estrogenic or androgenic activity. Proliferation rate of endometria from Polycystic Ovary Syndrome women ...
    • Hyperandrogenism Decreases GRP78 Protein Level and Glucose Uptake in Human Endometrial Stromal Cells 
      Rosas Chuñil, Carlos; Oróstica Arévalo, María Lorena; Poblete, Cristian; Carvajal Gavilán, Rodrigo; Gabler Neale, Fernando; Romero Osses, Carmen; Lavandero González, Sergio; Vega Blanco, María Margarita (SAGE, 2016)
      Background: Women with polycystic ovary syndrome (PCOS) exhibit a low fertility by chronic hyperandrogenemia. Different evidence have shown that androgens could regulate the endoplasmic reticulum (ER) homeostasis and glucose ...
    • Metformin augments the levels of molecules that regulate the expression of the insulin-dependent glucose ... 
      Rosas, Carlos; Kohan Ivani, Karla; Gabler Neale, Fernando; Vantman Bretschneider, David; Romero Osses, Carmen; Vega Blanco, María Margarita; Carvajal Gavilán, Rodrigo (Oxford University Press, 2013)
      study question: Does treatment with the insulin sensitizer metformin modify the levels and activation of proteins related to the expression of the insulin-dependent glucose transporter (GLUT4), such as adenosine ...
    • Niveles de hormona antimülleriana y factor neurotrófico derivado del cerebro como predictores de función ovárica 
      Carvajal Gavilán, Rodrigo; Alba, Juan F.; Cortínez Castro, Armando; Vantman Bretschneider, David; Carvajal M., Antonio; Miranda Venegas, Cristián; Romero Osses, Carmen (Hospital Clínico Universidad de Chile, 2012)
      Infertility is now recognized as a disease by World Health Organization. It affects up to 15% of couples of childbearing age and un 4-8% of them will require high complexity assisted reproduction techniques. The delay of ...
    • Proinflammatory environment and role of TNF-α in endometrial function of obese women having polycystic ... 
      Oróstica Arévalo, María Lorena; Astorga Leiva, Isis; Plaza Parrochia, Francisca; Vera Castillo, Carolina; García Angulo, Víctor; Carvajal Gavilán, Rodrigo; Gabler Neale, Fernando; Romero Osses, Carmen; Vega Blanco, María Margarita (Springer Nature, 2016)
      BACKGROUND/OBJECTIVES: A high percentage of women having polycystic ovarian syndrome (PCOS) exhibit hyperinsulinemia and obesity. Transforming necrosis factor-alpha (TNF-alpha) is an adipokine that increases in obesity and ...
    • Protein expression of PKCZ (Protein Kinase C Zeta), Munc18c, and Syntaxin-4 in the insulin pathway in ... 
      Rivero, Rodrigo; Garin, Claire-Alix; Ormazábal Leiva, Paulina Fernanda; Silva, Andrea; Gabler Neale, Fernando; Carvajal Gavilán, Rodrigo; Romero Osses, Carmen; Vega Blanco, María Margarita (2012)
      Background: Polycystic Ovary Syndrome (PCOS) is an endocrine-metabolic disorder commonly associated with insulin resistance (IR). Previous studies indicate about the expression of molecules involved in the insulin pathway in ...