Browsing by Author "XX676390"
Now showing items 1-20 of 24
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Oróstica Arévalo, María Lorena; Rosas Chuñil, Carlos; Plaza Parrochia, Francisca; Astorga Leiva, Isis; Gabler Neale, Fernando; García Angulo, Víctor; Romero Osses, Carmen; Vega Blanco, María Margarita (Bentham Science, 2016)Background: Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine/metabolic disorder characterized by hyperandrogenemia and in most cases, by hyper-insulinemia in addition to obesity. Besides ovarian dysfunction, ...
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Villavicencio, A.; Bacallao, Ketty; Avellaira, C.; Gabler Neale, Fernando; Fuentes, A.; Vega Blanco, María Margarita (2006)Objective.: To study if the endocrinological status of PCOS women affects the endometrial sensitivity to steroids by evaluating the expression of androgen receptor (AR), estrogen receptor α (ERα), estrogen receptor β (ERβ), ...
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Fornes, Romina; Ormazábal Leiva, Paulina Fernanda; Rosas, Carlos; Gabler Neale, Fernando; Vantman Bretschneider, David; Romero Osses, Carmen; Vega Blanco, María Margarita (2010-04)Polycystic ovary syndrome (PCOS) is an endocrine-metabolic disorder associated with insulin resistance and compensatory hyperinsulinemia. Scarce information is available on the expression of molecules involved in the ...
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Ormazábal Leiva, Paulina Fernanda; Romero Osses, Carmen; Gabler Neale, Fernando; Quest, Andrew F. G.; Vega Blanco, María Margarita (2013)Endometrial tissue of patients with polycystic ovary syndrome (PCOS) shows an impaired expression of insulin signaling molecules. Tyrosine phosphorylation of the insulin receptor (IR) by insulin promotes glucose uptake by ...
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Palomino Avilés, Wilder; Fuentes García, Frans; González, Rubén René; Gabler Neale, Fernando; Boric Scarpa, María Angélica; Vega Blanco, María Margarita; Devoto, Luigi (ELSEVIER, 2005-03)\Objective: To assess the effect of clomiphene citrate (CC) on endometrial epithelial integrins and P receptors (PR) during the window of implantation. Design: Controlled, prospective, clinical study. Setting: Teaching ...
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Valladares, Macarena; Plaza Parrochia, Francisca; Lepez, Macarena; López Ponce, Daniela; Gabler Neale, Fernando; Gayan, Patricio; Selman, Alberto; Vega Blanco, María Margarita; Romero Osses, Carmen (Francisco Hernández, Editor, 2017)Introduction: Ovarian cancer presents a high angiogenesis (formation of new blood vessels) regulated by pro-angiogenic factors, mainly vascular endothelial growth factor (VEGF) and nerve growth factor (NGF). An association ...
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Díaz Valdivia, Natalia; Bravo, Denisse; Huerta, Hernán; Henríquez, Soledad; Gabler Neale, Fernando; Vega Blanco, María Margarita; Romero Osses, Carmen; Calderón, Claudia; Owen, Gareth I.; Leyton Campos, Lisette; Quest, Andrew F. G. (BioMed Central, 2015)Background: Caveolin-1 (CAV1) has been implicated both in tumor suppression and progression, whereby the specific role appears to be context dependent. Endometrial cancer is one of the most common malignancies of the female ...
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Ormazábal, Paulina; Romero Osses, Carmen; Gabler Neale, Fernando; Quest, Andrew F. G.; Vega Blanco, María Margarita (2013)
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Quezada, Susana; Avellaira, Carla; Johnson Pena, María Cecilia; Gabler Neale, Fernando; Fuentes García, Frans; Vega Blanco, María Margarita (ELSEVIER, 2006-04)Objective: To evaluate gene and protein expression of steroid receptors, nuclear receptor coregulators, and uterine receptivity markers in midsecretory phase endometria from untreated women with polycystic ovary syndrome ...
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Avellaira, C.; Villavicencio, A.; Bacallao, Ketty; Gabler Neale, Fernando; Wells, P.; Romero Osses, Carmen; Vega Blanco, María Margarita (Oxford University Press, 2006)Background: The hormonal alterations observed in women with polycystic ovary syndrome (PCOS) may promote implantation failure as well as disruption of their endometrial homeostasis. To evaluate cell survival of mid-secretory ...
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Plaza Parrochia, Francisca; Poblete, Cristian; Gabler Neale, Fernando; Carvajal Gavilán, Rodrigo; Romero Osses, Carmen; Valladares Boasi, Luis; Vega Blanco, María Margarita (Elsevier, 2015)Intracrinology mechanism involves the metabolism of steroids in peripheral tissues, such as DHEA, to molecules with estrogenic or androgenic activity. Proliferation rate of endometria from Polycystic Ovary Syndrome women ...
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Cortínez Castro, Armando; De Carvalho, Iara; Vantman Bretschneider, David; Gabler Neale, Fernando; Iñíguez Vila, Germán; Vega Blanco, María Margarita (ELSEVIER SCIENCE INC, 2005-01)Objective: To evaluate the clinical response and endometrial morphology during the implantation window on ovarian hyperstimulation with the aromatase inhibitor letrozole in infertile ovulatory women. Design: Prospective ...
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Hyperandrogenism Decreases GRP78 Protein Level and Glucose Uptake in Human Endometrial Stromal Cells Rosas Chuñil, Carlos; Oróstica Arévalo, María Lorena; Poblete, Cristian; Carvajal Gavilán, Rodrigo; Gabler Neale, Fernando; Romero Osses, Carmen; Lavandero González, Sergio; Vega Blanco, María Margarita (SAGE, 2016)Background: Women with polycystic ovary syndrome (PCOS) exhibit a low fertility by chronic hyperandrogenemia. Different evidence have shown that androgens could regulate the endoplasmic reticulum (ER) homeostasis and glucose ...
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Bacallao, Ketty; Plaza Parrochia, Francisca; Cerda, A.; Gabler Neale, Fernando; Romero Osses, Carmen; Vantman Bretschneider, David; Vega Blanco, María Margarita (SAGE, 2016)Polycystic ovarian syndrome (PCOS) has been associated with endometrial hyperplasia and cancer. The aim of this study was to establish whether the expression of proliferation regulatory proteins in the endometria of ...
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Vera, C.; Tapia, V.; Kohan Ivani, Karla; Gabler Neale, Fernando; Ferreira, A.; Selman, A.; Vega Blanco, María Margarita; Romero Osses, Carmen (2012)Epithelial ovarian cancer is highly angiogenic and high expression of Nerve Growth Factor (NGF), a proangiogenic protein. Calreticulin is a multifunctional protein with anti-angiogenic properties and its translocation to ...
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Oróstica Arévalo, María Lorena; Astorga Leiva, Isis; Plaza Parrochia, Francisca; Vera Castillo, Carolina; García Angulo, Víctor; Carvajal Gavilán, Rodrigo; Gabler Neale, Fernando; Romero Osses, Carmen; Vega Blanco, María Margarita (Springer Nature, 2016)BACKGROUND/OBJECTIVES: A high percentage of women having polycystic ovarian syndrome (PCOS) exhibit hyperinsulinemia and obesity. Transforming necrosis factor-alpha (TNF-alpha) is an adipokine that increases in obesity and ...
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Rivero, Rodrigo; Garin, Claire-Alix; Ormazábal Leiva, Paulina Fernanda; Silva, Andrea; Gabler Neale, Fernando; Carvajal Gavilán, Rodrigo; Romero Osses, Carmen; Vega Blanco, María Margarita (2012)Background: Polycystic Ovary Syndrome (PCOS) is an endocrine-metabolic disorder commonly associated with insulin resistance (IR). Previous studies indicate about the expression of molecules involved in the insulin pathway in ...
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Kohan Ivani, Karla; Gabler Neale, Fernando; Selman,; Vega Blanco, María Margarita; Romero Osses, Carmen (Springer Verlag, 2016)© 2015, The Author(s).Purpose: One of the hypotheses regarding the genesis of epithelial ovarian cancer involves the action of androgens on the proliferation of epithelial ovarian cells, as well as inclusion cysts. The ...
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Kohan Ivani, Karla; Gabler Neale, Fernando; Selman Abuchaibe, Alberto; Vega Blanco, María Margarita; Romero Osses, Carmen (Springer, 2016)Purpose One of the hypotheses regarding the genesis of epithelial ovarian cancer involves the action of androgens on the proliferation of epithelial ovarian cells, as well as inclusion cysts. The purpose of the present ...
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Maliqueo Yevilao, Manuel; Bacallao, Ketty; Quezada, Susana; Clementi, Marisa; Gabler Neale, Fernando; Johnson, M. Cecilia; Vega Blanco, María Margarita (2007)Objective: To evaluate the protein and messenger RNA expression of sex hormone-binding globulin (SHBG) in endometria from women with polycystic ovary syndrome (PCOS). Design: Case-control study. Setting: Hospital research ...