Browsing by Author "XX676615"
Now showing items 1-20 of 27
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Kohen Skop, Paulina; Henríquez, Soledad; Rojas, Candy; Gerk, Phillip M.; Palomino Avilés, Wilder; Strauss, Jeroma F.; Devoto, Luigi (Elsevier, 2013-11)To quantitate 2-methoxyestradiol (2-ME) in human corpus luteum (CL) of different ages and to determine the expression of cytochrome-P450-1A1 (CYP1A1) and catechol-O-methyl transferase (COMT) in CL and the action of 2-ME ...
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Villarroel, Claudio; Salinas, A.; López, Patricia; Kohen Skop, Paulina; Rencoret, Gustavo; Devoto, Luigi; Codner Dujovne, Ethel (Taylor & Francis INC, 2018)Hyperandrogenemia and hyperinsulinemia are observed in women with diabetes during pregnancy. The effect of diabetes on anti-Mullerian hormone (AMH) levels during pregnancy is unclear. The aim of this study was to determine ...
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Villarroel, Claudio; Trejo, León; Muñoz, Alex; Kohen Skop, Paulina; Fuentes, Ariel; Devoto, Luigi (2010)Objective.This study was designed to assess the diagnostic potency of different androgens in hyperandrogenaemia criterion on polycystic ovary syndrome (PCOS) based on receiver operator characteristic (ROC) curves analysis. ...
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Palomino Avilés, Wilder; Argandoña, Felipe; Azúa, Rodrigo; Kohen Skop, Paulina; Devoto, Luigi (2013)The control of complement activation in the embryo–maternal environment has been demonstrated to be critical for embryo survival. Complement proteins are expressed in the human endometrium; however, the modulation of this ...
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Villarroel, Claudio; López, Patricia; Salinas, A.; Kohen Skop, Paulina; Rencoret, Gustavo; Codner Dujovne, Ethel (Sage Publications INC, 2018)
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Villarroel Quintana, Claudio; Salinas, A.; López, P.; Rencoret Palma, Gustavo Ignacio; Kohen Skop, Paulina; Codner Dujovne, Ethel (Karger, 2015)
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Estrogen metabolites in human corpus luteum physiology: differential effects on angiogenic activity Henríquez, Soledad; Kohen Skop, Paulina; Xu, Xia; Veenstra, Timothy D.; Muñoz, Alex; Palomino Avilés, Wilder; Strauss, Jerome F.; Devoto, Luigi (Elsevier, 2016)Objective: To determine tissue concentrations of E2, estrone, P, and estrogensmetabolites (EMs) 2-methoxyestradiol, 2-methoxyestrone, 4-hydroxyestrone, and 16-ketoestradiol in corpus luteum(CL) of different ages, and after ...
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Del Canto, Felipe; Sierralta, Walter; Kohen Skop, Paulina; Ferrada Muñoz, Alex Eduardo; Strauss, Jerome F.; Devoto, Luigi (Endocrine Society, 2007)Context: The natural process of luteolysis and luteal regression is induced by withdrawal of gonadotropin support. Objective: The objectives of this study were: 1) to compare the functional changes and apoptotic features ...
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Devoto, Luigi; Kohen Skop, Paulina; Barnhart, Kurt; Alba, Francisco; Pommer, Ricardo; Retamales, Ivan; Coutinho, Elzimar (Oxford University Press, 1997)The present study assesses the endocrinological, endometrial histology and vaginal ultrasound profiles of nomegestrol acetate subdermal implant users at varying times after insertion. Follicle stimulatory hormone, luteinizing ...
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Human corpus luteum physiology and the luteal-phase dysfunction associated with ovarian stimulation Devoto, Luigi; Kohen Skop, Paulina; Ferrada Muñoz, Alex Eduardo; Strauss, Jerome F. (Reproductive Healthcare Ltd, 2009)The human corpus luteum is a temporary endocrine gland that develops after ovulation from the ruptured follicle during the luteal phase. It is an important contributor of steroid hormones, particularly progesterone, and ...
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Vega Blanco, María Margarita; Devoto, Luigi; Navarro, Veronica; Castro, Olga; Kohen Skop, Paulina (1987)Slices of human corpora lutea (CL) obtained at varying stages of the luteal phase from 21 women were used to study the effect of hCG on progesterone (P4) production. Slices obtained from mid- and late CL incubated with 10 ...
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Henríquez Barrera, Soledad; Kohen Skop, Paulina; Muñoz Gallardo, Alex; Godoy, Ana; Orge, Felipe; Strauss, Jerome F.; Devoto, Luigi (Elsevier, 2017)In humans, data on gonadotrophin-activated (LH, HCG and FSH) progesterone receptor expression and signalling pathways involved in matrix metalloproteinases (MMPs) expression presumably linked to the follicle rupture, are ...
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Castro, Andrea; Castro, Olga; Troncoso, José Luis; Kohen Skop, Paulina; Simon, Carlos; Vega Blanco, María Margarita; Devoto, Luigi (Oxford University Press, 1998)Flow cytometry analysis of luteal cells revealed that an important proportion of these cells are leukocytes. The percentage of leukocytes was higher in the early (42 ± 4) and late (35 ± 3) luteal phases than in the mid-luteal ...
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Poch, Andrea; Villanelo, Felipe; Henriquez, Soledad; Kohen Skop, Paulina; Ferrada Muñoz, Alex Eduardo; Strauss, Jerome F.; Devoto, Luigi (Elsevier Inc., 2019)An estradiol metabolite, 2-methoxyestradiol (2ME), has emerged as an important regulator of ovarian physiology. 2ME is recognized as a potent anti-angiogenic agent in clinical trials and laboratory studies. However, little ...
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Devoto, Luigi; Palomino, Alberto; Céspedes, Pablo; Kohen Skop, Paulina (2012)The ovarian aging, a dynamic process that precedes the clinical manifestations of menopause, can be assessed using ovarian reserve biomarkers. It is well-known that reproduction during the later years of reproductive life ...
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Villarroel Quintana, Claudio; López Romero, Patricia Eugenia; Salinas Quero, Soledad; Kohen Skop, Paulina; Rencoret Palma, Gustavo Ignacio; Codner Dujovne, Ethel (Karger, 2017)
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Devoto, Luigi; Fuentes, Ariel; Palomino, Alberto; Espinoza Muñoz, Alejandra; Kohen Skop, Paulina; Ranta, Sirpa; von Hertzen, Helena (ELSEVIER SCIENCE INC, 2005-07)Objective: To determine the pharmacokinetics and endometrial tissue levels of levonorgestrel when taken as a single dose of 1.5 mg either orally or vaginally by healthy women in the periovulatory phase of their menstrual ...
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González Ramos, Reinaldo; Rocco, Jocelyn; Rojas, Candy; Sovino, Hugo; Devoto, Luigi; Poch, Andrea; Kohen Skop, Paulina; Alvarado Díaz, Carlos; Devoto, Luigi (Elsevier, 2012-03)Objective: To evaluate nuclear factor kappaB (NF-kB) activation and NF-kB–p65 subunit activation, immunolocalization, and expression in the endometrium of healthy women and endometriosis patients throughout the menstrual ...
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Villarroel Quintana, Claudio; Salinas Quero, Soledad Abril; López Cuevas, Patricia; Kohen Skop, Paulina; Rencoret Palma, Gustavo; Devoto, Luigi; Codner Dujovne, Ethel (Taylor and Francis, 2017)Higher androgen levels are observed in non-pregnant women with diabetes. Whether thishormonal profile is found during pregnancy is unknown. The aim of this study was todetermine the sexual steroids levels in pregnant women ...
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Vega Blanco, María Margarita; Devoto, Luigi; Castro, Olga; Kohen Skop, Paulina (1994)To assess the role of estradiol (E2) upon progesterone (P4) synthesis, a well defined human midluteal cell system was used. A dose-dependent inhibition of P4 synthesis with and without hCG was induced by E2. In addition, ...