Browsing by Author "XX676695"

Now showing items 1-9 of 9

    • A heat-shocked melanoma cell lysate vaccine enhances tumor infiltration by prototypic effector T cells ... 
      Gleisner Muñoz, María Alejandra; Pereda Ramos, Cristián; Tittarelli Elaskar, Andrés; Navarrete Sánchez, Mariela; Fuentes Villegas, Camila; Ávalos, Ignacio; Tempio Sepúlveda, Fabián; Araya, Juan Pablo; Becker, María Inés; González Bergas, Fermín; López Nitsche, Mercedes; Salazar Onfray, Flavio (BMJ, 2020)
      Background Immune checkpoint blocker (ICB) therapy has shown survival benefits for some patients with cancer. Nevertheless, many individuals remain refractory or acquire resistance to treatment, motivating the exploration of ...
    • Adenosine A(3) receptor elicits chemoresistance mediated by multiple resistance-associated protein-1 in ... 
      Torres, Angelo; Vargas, Yosselyn; Uribe, Daniel; Jaramillo, Catherine; Gleisner Muñoz, María Alejandra; Salazar Onfray, Flavio; López Nitsche, Mercedes; Melo, Rómulo; Oyarzún, Carlos; San Martín, Rody; Quezada, Claudia (Impact Journals LLC, 2016)
      MRP1 transporter correlates positively with glioma malignancy and the Multiple Drug Resistance (MDR) phenotype in Glioblastoma Multiforme (GBM). Evidence shows that the MRP1 transporter is controlled by the adenosine ...
    • High CD8(+) and absence of Foxp3(+) T lymphocytes infiltration in gallbladder tumors correlate with prolonged ... 
      Fluxá Rojas, Paula; Rojas Sepúlveda, Daniel; Gleisner, María Alejandra; Tittarelli, Andrés; Villegas, Pablo; Tapia, Loreto; Rivera, María Teresa; López Nitsche, Mercedes; Catán, Felipe; Uribe Maturana, Mario; Salazar Onfray, Flavio (BIOMED Central Ltd., 2018)
      Background: Gallbladder cancer (GBC), although infrequent in industrialized countries, has high incidence rates in certain world regions, being a leading cause of death among elderly Chilean women. Surgery is the only ...
    • The immunological response and post-treatment survival of DC-vaccinated melanoma patients are associated ... 
      Durán Aniotz, Claudia; Segal, Gabriela; Salazar, Lorena; Pereda, Cristián; Falcón, Cristián; Tempio, Fabián; Aguilera, Raquel; González González, Rodrigo; Pérez Núñez, Claudio; Tittarelli, Andrés; Catalán Martina, Diego; Nervi, Bruno; Larrondo Lillo, Milton; Salazar Onfray, Flavio; López Nitsche, Mercedes (Springer, 2013)
      Introduction Immunization with autologous dendritic cells (DCs) loaded with a heat shock-conditioned allogeneic melanoma cell lysate caused lysate-specific delayed type hypersensitivity (DTH) reactions in a number ...
    • In vitro phenotype induction of circulating monocytes: CD16 and CD163 analysis 
      Karsulovic Cvitanich, Claudio; Tempio, Fabián; López Nitsche, Mercedes; Guerrero Peralta, Julia; Goecke Sariego, Irmgadt (Dove Medical Press, 2021)
      Introduction: CD14 (monocyte differentiation antigen, LPS binding protein - endotoxin receptor) and CD16 (FcyRIII, Low-affinity receptor for IgG) define three subpopulations of circulating monocytes with different inflammatory ...
    • Increased M1 inflammatory phenotype of circulating monocytes is associated with history of cardiovascular ... 
      Goecke Sariego, Annelise; Karsulovic Cvitanich, Claudio; Guerrero Peralta, Julia; Tempio Sepúlveda, Fabián; López Nitsche, Mercedes (BMJ, 2020)
    • mTORC inhibitor Sirolimus deprograms monocytes in “cytokine storm” in SARS-CoV2 secondary hemophagocytic ... 
      Karsulovic Cvitanich, Claudio; López Nitsche, Mercedes; Tempio Sepúlveda, Fabián; Guerrero Peralta, Julia; Goecke Sariego, Irmgadt (Elsevier, 2020)
    • Nuevas armas inmunológicas para la medicina del siglo XXI: Terapia biológica basada en el uso de anticuerpos ... 
      Aguillón Gutiérrez, Juan Carlos; Contreras L., Juan; Dotte G., Andrés; Cruzat C., Andrea; Catalán Martina, Diego; Salazar A., Lorena; Molina S., María Carmen; Guerrero P., Julia; López Nitsche, Mercedes; Soto Sáez, Lilian; Salazar Onfray, Flavio; Cuchacovich Turteltaub, Miguel (Sociedad Médica de Santiago, 2003)
      The fusion of a murine B cell and a myeloma cell generates a hybridoma that produces monoclonal antibody (mAb). These murine mAb induce the HAMA (human anti-mouse antibodies) response. Murine mAb have been modified by ...
    • Paradoxical effects of cytokines in tumor immune surveillance and tumor immune escape 
      Salazar Onfray, Flavio; López Nitsche, Mercedes; Mendoza Naranjo, Ariadna (2007)
      The role of cytokines in modulating the formation of new tumors is mediated by their ability to regulate antigen-specific anti-tumor responses and by the activation of non-specific mechanisms, including those involved in ...