Browsing by Author "XX676959"
Now showing items 1-8 of 8
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(Mary Ann Liebert Inc publishers, 2018)Aims: Previous studies indicate that hippocampal synaptic plasticity and spatial memory processes entail calcium release from intracellular stores mediated by ryanodine receptor (RyR) channels. In particular, RyR-mediated ...
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(Elsevier, 2020)During spatial navigation, some typical parameters of learning have been observed, such as latency or path length. However, these parameters are sensitive to patterns of navigation and orientation that are not easily ...
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(Universidad de Chile, 2016)"La Astaxantina protege a las neuronas de cultivo primario de hipocampo de los efectos dañinos de los oligómeros del peptido β-amiloide " Introducción: El incremento en la producción de especies reactivas de oxígeno y la ...
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(Wiley & Sons, 2015)BackgroundThe mechanisms involved in reactive oxygen species and matrix metalloproteinase (MMP)-mediated periodontal tissue breakdown are unknown. ObjectiveTo determine the effect of H2O2 in MMP-2 and MMP-9 activity, ...
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(Elsevier, 2015)Ryanodine is a cell permeant plant alkaloid that binds selectively and with high affinity to ryanodine receptor (RyR) Ca2þ release channels. Sub-micromolar ryanodine concentrations activate RyR channels while micromolar ...
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(Elsevier, 2018)The transcription factor STAT3 has a crucial role in the development and maintenance of the nervous system. In this work, we treated astrocytes with oligomers of the amyloid beta peptide (A beta Os), which display potent ...
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Small-molecule aggregation inhibitors reduce excess amyloid in a trisomy 16 mouse cortical cell line (SOC BIOLGIA CHILE, 2008)We have previously characterized a number of small molecule organic compounds that prevent the aggregation of the β-amyloid peptide and its neurotoxicity in hippocampal neuronal cultures. We have now evaluated the effects ...
