Now showing items 1-20 of 20

    • Lardone, María Cecilia; Busch, Alexander; Santos, José; Miranda, Patricio; Eyheramendy, Susana; Pereira Scalabrino, Ana; Juul, Anders; Almstrup, Kristian; Mericq, Verónica (Endocrine Society, 2020)
      Context: Voice break, as a landmark of advanced male puberty in genome-wide association studies (GWAS), has revealed that pubertal timing is a highly polygenic trait. Although voice break is easily recorded in large cohorts, ...
    • Lardone, María Cecilia; Castro, Andrea; Ortiz, Eliana; Pereira Scalabrino, Ana; Corvalán Aguilar, Camila; Mericq, Verónica (Karger, 2017)
    • Binder, Alexandra M.; Corvalán Aguilar, Camila; Calafat, Antonia M.; Ye, Xiaoyun; Mericq, Verónica; Pereira Scalabrino, Ana; Michels, Karin B. (BIOMED Central Ltd., 2018)
      Background: The age of menarche has been associated with metabolic and cardiovascular disease, as well as cancer risk. The decline in menarcheal age over the past century may be partially attributable to increased exposure ...
    • Gaskins, Audrey J.; Pereira Scalabrino, Ana; Quintiliano Scarpelli, Daiana; Shepherd, John A.; Uauy Dagach-Imbarack, Ricardo; Corvalán Aguilar, Camila; Michels, Karin B. (American Society for Nutrition, 2017-05-01)
      Background: Frequent dairy consumption in childhood has been related to higher growth-hormone concentrations that may affect mammary gland and pubertal development. Objective: We evaluated the relation of dairy intake ...
    • Mericq, Verónica; Pereira Scalabrino, Ana; Uauy Dagach-Imbarack, Ricardo; Corvalán Aguilar, Camila (Karger, 2017)
      Background: Accelerated weight and height gain in infancy have been associated with premature adrenarche. However, the exact tempo of these events remains undefined. Thus, our goal was to assess the relationship between ...
    • Cuzmar, Valeriau; Alberti, Gigliola; Uauy Dagach-Imbarack, Ricardo; Pereira Scalabrino, Ana; García, Cristian; De Barbieri, Florencia; Corvalán Aguilar, Camila; Santos, José L.; Mericq Guila, Verónica; Villarroel, Luis; Gana, Juan Cristóbal (Lippincott Williams & Wilkins, 2020)
      Nonalcoholic fatty liver disease (NAFLD), defined as fat accumulation greater than 5% in hepatocytes, may progress to fibrosis or cirrhosis later in life. NAFLD prevalence in adolescents has increased significantly in ...
    • López, Ana; Garmendia Miguel, María Luisa; Shepherd, John; Michels, Karin; Corvalán Aguilar, Camila; Pereira Scalabrino, Ana (Nature, 2020)
      The effect of excessive gestational weight gain (EGWG) is related to adverse health outcomes in the offspring; however, its effect on the daughters' breast density is unclear. We aimed to assess the association between ...
    • Binder, Alexandra M.; Corvalán Aguilar, Camila; Mericq, Verónica; Pereira Scalabrino, Ana; Santos, José Luis; Horvath, Steve; Shepherd, John; Michels, Karin B. (Taylor & Francis, 2018)
      Epigenetic age is an indicator of biological aging, capturing the impact of environmental and behavioral influences across time on cellular function. Deviance between epigenetic age and chronological age (AgeAccel) is a ...
    • Busch, Alexander S.; Hagen, Casper P.; Main, Katharina M.; Pereira Scalabrino, Ana; Corvalán Aguilar, Camila; Almstrup, Kristian; Mericq, Verónica; Juul, Anders (Oxford Academic, 2017)
      Context: Although genetic factors play a pivotal role in male pubertal timing, genome-wide association studies have identified only a few loci. Genetic variation of follicle-stimulating hormone (FSH) action affects adult ...
    • Pereira Scalabrino, Ana; Corvalán Aguilar, Camila; Merino Osorio, Paulina; Iñíguez Vila, Germán; Mericq, Verónica (Karger, 2017)
    • Pereira Scalabrino, Ana; Iñíguez Vila, Germán; Corvalán Aguilar, Camila; Mericq, Verónica (Oxford, 2017)
      Context: Premature adrenarche (PA) has been associated with increased metabolic risk. Objective: To describe the risk of precocious thelarche (PT; ,8 years), pubarche (PP; girls ,8 years, boys ,9 years), and gonadarche ...
    • McCormack, Valerie; Burton, Anya; Santos Silva, Isabel dos; Hipwell, John; Dickens, Caroline; Salem, Dorria; Kama, Rasha; Hartman, Mikael; Lee, Charmaine Pei Ling; Chiah, Kee-Seng; Ozmen, Vahit; Aribal, Mustafa Erkin; Flugelman, Anath Arzee; Lajous, Martín; López Riduara, Ruy; Rice, Megan; Romieun, Isabelle; Ursin, Giske; Qureshi, Samera; Ma, Huiyan; Lee, Eunjung; van Gils, Carla; Wanders, Johanna; Vinayak, Sudhir; Ndumia, Rose; Allen, Steve; Vinnicombe, Sarah; Moss, Sue; Lee, Jong Won; Kim, Jisun; Pereira Scalabrino, Ana; Garmendia Miguel, María Luisa; Sirous, Reza; Sirous, Mehri; Peplonska, Beata; Bukowska, Agnieszka; Tamimi, Rulla; Bertrand, Kimberly; Nagata, Chisato; Kwong, Ava; Vachon, Celine; Scott, Christopher; Pérez Gómez, Beatriz; Pollan, Marina; Maskarinec, Gertraud; Giles, Graham; Hopper, John; Stone, Jennifer; Rajaram, Nadia; Teo, Soo Hwang; Mariapun, Shivaani; Yaffe, Martín; Schuez, Joachim; Chiarelli, Anna; Linton, Linda; Boyd, Norman (Elsevier, 2016)
      Mammographic density (MD) is a quantitative trait, measurable in all women, and is among the strongest markers of breast cancer risk. The population-based epidemiology of MD has revealed genetic, lifestyle and societal/e ...
    • Merino Osorio, Paulina; Pereira Scalabrino, Ana; Iñíguez Vila, Germán; Corvalán Aguilar, Camila; Mericq, Verónica (Karger, 2016)
    • Burton, Anya; Maskarinec, Gertraud; Pérez Gómez, Beatriz; Pereira Scalabrino, Ana; Garmendia Miguel, MarÍa Luisa (Public Library Science, 2017)
      Background Mammographic density (MD) is one of the strongest breast cancer risk factors. Its age-related characteristics have been studied in women in western countries, but whether these associations apply to women ...
    • Martínez Arroyo, Ángela; Moreno Macías, Hortensia; Pereira Scalabrino, Ana; Garmendia Miguel, María Luisa (Routledge, 2017)
      Background: Metabolic syndrome (MetS) has been previously associated with an increased risk of breast cancer in postmenopausal women. Mammographic density (MD) is a marker of breast cancer risk. There is little evidence ...
    • Mesa Valencia, Diana Carolina; Mericq, Verónica; Corvalán Aguilar, Camila; Pereira Scalabrino, Ana (Taylor & Francis, 2020)
      Purpose: Recent reports show that girls with higher body mass index (BMI) have an earlier puberty onset (thelarche). It has been suggested that earlier puberty is a consequence of higher levels of estrogen due to increased ...
    • Pereira Scalabrino, Ana; Valenzuela Bravo, María Teresa; Mora, Judith; Vera, Lilian (2008)
      Background: Hepatitis B virus infection generates carriers and 8% will evolve to a chronic phase. Aim: To perform a compilation of studies on hepatitis B in Chile and other sources of information to estimate the impact of ...
    • Fernández Garay, María Soledad; Pereira Scalabrino, Ana; Corvalán Aguilar, Camila; Mericq, Verónica (Karger, 2016)
    • Garmendia, María Luisa; Pereira Scalabrino, Ana; Alvarado, María Elena; Atalah Samur, Eduardo (2007)
      Purpose: In Chile, diabetes and breast cancer are important public health problems. The association between insulin resistance and breast cancer, however, remains largely unexplored. Methods: We conducted a case-control ...
    • Soto, Julio; Pereira Scalabrino, Ana; Busch, Alexander Siegfried; Almstrup, Kristian; Corvalán Aguilar, Camila; Iñíguez Vila, Germán; Juul, Anders; Mericq Guila, Verónica (Wiley, 2020)
      Context Transient thelarche (TT), that is, the appearance, regression and subsequent reappearance of breast buds, is a frequent phenomenon, but little is known about pubertal transition in these girls. Objective To describe ...