Now showing items 1-20 of 53

    • Santos, José Luis; Lera Marques, Lydia; Pérez Bravo, Francisco; Albala Brevis, Cecilia (2006)
      Background: It has been proposed that the toll-like receptor-4 gene (TLR4) may participate in the development of obesity and osteoporosis, in addition to its well-known role in the immune response. On the other hand, the ...
    • Gajardo Carrasco, Tania; Morales, Rodrigo A.; Pérez Bravo, Francisco; Terraza, Claudia; Yáñez, Luz; Campos Mora, Mauricio; Pino Lagos, Karina (Frontiers Research Foundation, 2015)
      IL-33 is a known member of the IL-1 cytokine superfamily classically named “atypical” due to its diverse functions. The receptor for this cytokine is the ST2 chain (or IL-1RL1), part of the IL-1R family, and the accessory ...
    • Santos M., José Luis; Patiño G., Ana; Ángel Badillo, Bárbara; Martínez H., José Alfredo; Pérez Bravo, Francisco; Villarroel B., Ana Claudia; Sierrasesúmaga A., Luis; Albala Brevis, Cecilia (SOC MEDICA SANTIAGO, 2006-09)
      Background: Tumor necrosis factor-alpha (TNF-alpha) has an increased expression in the adipose tissue of obese subjects and is involved in insulin resistance. Aim: To screen for associations between -308G/A, -238G/A, -376G/A ...
    • Galgani Fuentes, José; Vásquez, Karla; Leonelli, Giannella; Espinosa, Alejandra; Araya, Hector; Pérez Bravo, Francisco (2012)
      The aim of this study was to assess red blood cell glutathione from insulin-sensitive and insulin-resistant individuals before and after an oral glucose dose. Fifteen healthy, young (24 ± 5 years), nonobese (23 ± 2 kg·m ...
    • Araya, Magdalena; Diaz, Julia; Oyarzún, Amaya; Lucero, Yalda; Alarcón, Teresa; Gonzalez, Monica; Canales, Paulina; Fierro, Liliana; Pérez Bravo, Francisco (Lippincott Williams & Wilkings, 2018-05)
      Background: Current reports applying ESPGHAN exception criteria (EEC) to diagnose celiac disease (CD) without duodenal biopsies indicate that a high percentage of patients with CD may be identified when applied correctly ...
    • Duarte, Lissette; García Díaz, Diego; Pérez Bravo, Francisco (Korean Soc Pediatric Endocrinology, 2020)
      Purpose-Type 1 diabetes (T1D) is an autoimmune disease that involves genetic, epigenetic, and environmental factors. Change in body composition is a potential mechanism for explaining the increased incidence of T1D. Micro ...
    • Soto, Néstor; Pruzzo, Roxana; Eyzaguirre, Francisca; Iñíguez Vila, Germán; López, Patricia; Mohr, Jacqueline; Pérez Bravo, Francisco; Cassorla Goluboff, Fernando; Codner Dujovne, Ethel (Elsevier, 2011)
      This paper has two purposes: one conceptual and the other practical. On a conceptual level, it outlines a model for understanding how TV operates as a social mediator in the event of natural disasters, and at the practical ...
    • Codner Dujovne, Ethel; Merino Osorio, Paulina; Martínez Peña, David; López Egaña, Pedro; Godoy, C.; Iñíguez Vila, Germán; Cassorla Goluboff, Fernando; Pérez Bravo, Francisco (Wiley & Sons, 2016)
      AimsTo evaluate C-reactive protein, insulin growth factor1 and lipid levels during the follicular and luteal phases in adolescents with Type1 diabetes. MethodsAdolescents with Type1 diabetes (N=40) and healthy controls ...
    • Lucero Álvarez, Yalda; Oyarzún, Amaya; O'Ryan Gallardo, Miguel; Valenzuela, Romina; Farfán Urzúa, Mauricio; Gajardo, Iván; Ossa Alemparte, Juan; Pérez Bravo, Francisco (Frontiers media SA, 2017)
    • Cárdenas, César; Müller, Marioly; Jaimovich Pérez, Enrique; Pérez Bravo, Francisco; Buchuk, Diego; Quest, Andrew F. G.; Carrasco Friz, María Angélica (AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2004-09-10)
      Membrane depolarization of skeletal muscle cells induces slow inositol trisphosphate-mediated calcium signals that regulate the activity of transcription factors such as the cAMP-response element-binding protein (CREB), ...
    • Echiburú López, Bárbara; Milagro, Fermín; Crisosto King, Nicolás; Pérez Bravo, Francisco; Flores Ramírez, Cristián; Arpón, Ana; Salas Pérez, Francisca; Recabarren, Sergio E.; Sir-Petermann, Teresa; Maliqueo, Manuel (Taylor & Francis, 2020)
      Clinical and experimental evidences indicate that epigenetic modifications induced by the prenatal environment are related to metabolic and reproductive derangements in polycystic ovary syndrome (PCOS). Alterations in the ...
    • Araya, Magdalena; Oyarzún, Amaya; Lucero Álvarez, Yalda; Espinosa, Nelly; Pérez Bravo, Francisco (MDPI AG, 2015)
      HLA-linked genes are relevant to celiac disease (CD); the potential genetic differences present worldwide are not fully understood. Previous results suggest that the distribution of HLA-DQ2/DQ7/DQ8 in Chile may differ from ...
    • Merino Osorio, Paulina; Martínez, Daniela; Iñíguez Vila, Germán; López, Patricia; Cassorla Goluboff, Fernando; Pérez Bravo, Francisco; Codner Dujovne, Ethel (Informa Healthcare, 2015)
      Introduction: Variations in inflammatory markers have been reported in adult women during the luteal phase, but whether these findings are observed during adolescence is unknown. We postulate that higher ultrasensitive ...
    • Echiburú López, Bárbara; Pérez Bravo, Francisco; Galgani Fuentes, José; Sandoval, Daniel; Saldías, Carolina; Crisosto King, Nicolás; Maliqueo Yevilao, Manuel; Sir Petermann, Teresa (Elsevier Science INC, 2018)
      Context Polycystic ovary syndrome (PCOS) is an androgen excess disorder associated with obesity and adipose tissue disturbances. Our aim was to evaluate gene expression of adipocytokines and adipocyte characteristics in ...
    • Rozowski Narkunska, Jaime; Castillo Valenzuela, Oscar; Figari Jullian, Nicole; García Díaz, Diego; Cruchet Muñoz, Sylvia; Weisstaub Nuta, Sergio; Pérez Bravo, Francisco; Gotteland Russel, Martín (Aula Médica Ediciones, 2015)
      Background: The fact that deficient or even marginal nutritional levels may contribute to increase morbidity and mortality in the surgical patient is well accepted. The usefulness of vitamin and mineral markers has not ...
    • González R., Nelly; Torres Avilés, Francisco; Carrasco Piña, Elena; Salas P., Francisca; Pérez Bravo, Francisco (Rev Med Chile, 2013)
      Background: Pollution and viral infections could be associated with the incidence of type 1 diabetes mellitus. Aim: To look for associations between the temporal patterns of Type 1 Diabetes Mellitus (T1D) in infants ...
    • Ladrón de Guevara, Amanda; Crisosto King, Nicolás; Echiburú López, Bárbara; Preisler, Jessica; Vantman, Natalie; Bollmann, Josefina; Pérez Bravo, Francisco; Sir Petermann, Lidia (Elsevier Ireland Ltd., 2013)
      Objective: To assess gonadotrophin secretion, ovarian steroid production and ovarian reserve in PCOS women during the onset of reproductive decline, in order to characterize their ovarian function at this age. Study ...
    • García Díaz, Diego; Pizarro, Carolina; Camacho Guillen, Patricia; Codner Dujovne, Ethel; Soto, Nestor; Pérez Bravo, Francisco (Sbem-Soc Brasil Endocrinología & Metabología, 2018)
      Objective: The aim of this research was to analyze the expression profile of miR-155, miR-146a, and miR-326 in peripheral blood mononuclear cells (PBMC) of 47 patients with type 1 diabetes mellitus (T1D) and 39 control ...
    • Estrella, Santiago; García Díaz, Diego; Codner Dujovne, Ethel; Camacho Guillen, Patricia; Pérez Bravo, Francisco (2016)
      Background and objective: Type 1 diabetes (T1D) is an autoimmune disease of complex aetiology. Several microRNAs (miR) have been linked to the pathogenesis of autoimmune diseases. To analyze the possible association ...
    • Albala Brevis, Cecilia; Villarroel, Ana; Santos, José Luis; Ángel Badillo, Bárbara; Lera Marques, Lydia; Liberman Guendelman, Claudio; Sánchez, Hugo; Pérez Bravo, Francisco (Diabetes Research and Clinical Practice, 2007-08)
      Objective: The FABP2 Ala54Thr polymorphism has been associated with insulin resistance and diabetes in several populations. The aim of this study was to estimate the prevalence of FABP2 genotypes in 223 Chilean subjects ...