Now showing items 1-16 of 16

    • Pereira Montecinos, Camila; Peñailillo Cabrera, Nora; Valiente Echeverría, Fernando; Soto Rifo, Ricardo (2016)
    • Órdenes Aenishanslins, Nicolás; Anziani Ostuni, Giovanni; Monrás, Juan Pablo; Tello, Alejandra; Bravo Rodríguez, Denisse; Toro Ascuy, Daniela; Soto Rifo, Ricardo; Prasad, Paras N.; Pérez Donoso, José (MDPI, 2020)
      In this study, we introduce a biological method for the production of ternary Quantum Dots (QDs): complex nanostructures with tunable optical and structural properties that utilizes post-synthesis modifications through ...
    • García de Gracia, Francisco; Gaete Argel, Aracelly; Riquelme Barrios, Sebastián; Pereira Montecinos, Camila; Rojas Araya, Bárbara; Aguilera, Paulina; Oyarzún Arrau, Aarón; Rojas Fuentes, Cecilia; Acevedo, Mónica L.; Chnaiderman Figueroa, Jonás; Valiente Echeverría, Fernando; Toro Ascuy, Daniela; Soto Rifo, Ricardo (Taylor & Francis, 2020)
      Translation initiation of the human immunodeficiency virus type-1 (HIV-1) full-length RNA has been shown to occur through cap-dependent and IRES-driven mechanisms. Previous studies suggested that the nuclear cap-binding ...
    • Oyarzún Arrau, Aarón; Alonso-Palomares, Luis; Valiente Echeverría, Fernando; Osorio Olivares, Fabiola; Soto Rifo, Ricardo (MDPI, 2020)
      Zika virus (ZIKV) is a mosquito-borne virus associated with neurological disorders such as Guillain-Barré syndrome and microcephaly. In humans, ZIKV is able to replicate in cell types from di erent tissues including ...
    • Soto Rifo, Ricardo; Rubilar, Paulina S.; Ohlmann, Théophile (Oxford University Press, 2013)
      Here, we show a novel molecular mechanism promoted by the DEAD-box RNA helicase DDX3 for translation of the HIV-1 genomic RNA. This occurs through the adenosine triphosphate-dependent formation of a translation initiation ...
    • Fröhlich, Álvaro; Rojas Araya, Bárbara; Pereira Montecinos, Camila; Dellarossa, Alessandra; Toro Ascuy, Daniela; Prades Pérez, Yara; García de Gracia, Francisco; Garcés Alday, Andrea; Rubilar, Paulina S.; Valiente Echeverría, Fernando; Ohlmann, Théophile; Soto Rifo, Ricardo (Elsevier, 2016)
      DEAD-box RNA helicase DDX3 is a host factor essential for HIV-1 replication and thus, a potential target for novel therapies aimed to overcome viral resistance. Previous studies have shown that DDX3 promotes nuclear ...
    • Fröhlich, Alvaro; Rojas Araya, Bárbara; Pereira Montecinos, Camila; Dellarossa, Alessandra; Toro Ascuy, Daniela; Prades Pérez, Yara; García de Gracia, Francisco; Garcés Alday, Andrea; Rubilar, Paulina S.; Valiente Echeverría, Fernando; Ohlmann, Théophile; Soto Rifo, Ricardo (2016)
      DEAD-box RNA helicase DDX3 is a host factor essential for HIV-1 replication and thus, a potential target for novel therapies aimed to overcome viral resistance. Previous studies have shown that DDX3 promotes nuclear ...
    • Ung, Devina; Boitnott, Andrea; Mendonca, Danielle; Niblo, Kristi; Soto Rifo, Ricardo; Drapeau, Elodie; Buxbaum, Joseph D.; Rasin, Roko-Mladen; De Rubeis, Silvia (Elsevier, 2020)
    • Loreto Acevedo, Mónica; García de Gracia, Francisco; Miranda Cárdenas, Camila; Soto Rifo, Ricardo; Aguayo González, Francisco; Leon Decap, Oscar (Elsevier, 2018)
      Self-inactivating VSVG-pseudotyped murine leukemia virus (SIN-VSVG-MLV) has been widely used to generate stable cell lines and produce gene delivery vectors. Despite the broad cellular tropism of the VSVG-pseudotyped MLV, ...
    • Velásquez Salinas, Felipe; Marín Rojas, Josefina; Soto Rifo, Ricardo; Torres, Alexia; Canto Fuentes, Felipe del; Valiente Echeverría, Fernando (MDPI, 2021)
      Escherichia coli, one of the most abundant bacterial species in the human gut microbiota, has developed a mutualistic relationship with its host, regulating immunological responses. In contrast, enterotoxigenic E. coli ...
    • Lévican Asenjo, Jorge; Miranda Cárdenas, Camila; Soto Rifo, Ricardo; Aguayo González, Francisco; Gaggero Brillouet, Aldo; León Decap, Oscar (Nature Publishing Group, 2017-06-08)
      Infectious pancreatic necrosis virus (IPNV) is a non-enveloped virus belonging to the Birnaviridae family. IPNV produces an acute disease in salmon fingerlings, with high mortality rates and persistent infection in survivors. ...
    • Zhu, Liting; Liu, Xiaobo; Huang, Haining; Avellán Llaguno, Ricardo David; Llaguno Lazo, Mauricio Manuel; Gaggero Brillouet, Aldo; Soto Rifo, Ricardo; Patiño, Leandro; Valencia Avellan, Magaly; Diringer, Benoit; Huang, Qiansheng; Zhu, Yong-Guan (Elsevier, 2020)
      The role of meteorological factors in the transmission of the COVID-19 still needs to be determined. In this study, the daily new cases of the eight severely affected regions in four countries of South America and their ...
    • Hernández Díaz, Tomás; Valiente Echeverría, Fernando; Soto Rifo, Ricardo (MDPI, 2021)
      DDX3 is a cellular ATP-dependent RNA helicase involved in different aspects of RNA metabolism ranging from transcription to translation and therefore, DDX3 participates in the regulation of key cellular processes including ...
    • Valiente Echeverría, Fernando; Hermoso Ramello, Marcela; Soto Rifo, Ricardo (Wiley-Blackwell, 2015)
      Asp-Glu-Ala-Asp (DEAD)-box polypeptide 3, or DDX3, belongs to the DEAD-box family of ATP-dependent RNA helicases and is known to play different roles in RNA metabolism ranging from transcription to nuclear export, ...
    • Rojas Araya, Bárbara; Ohlmann, Theophile; Soto Rifo, Ricardo (MDPI AG, 2015)
      Post-transcriptional control in both HIV-1 and HIV-2 is a highly regulated process that commences in the nucleus of the host infected cell and finishes by the expression of viral proteins in the cytoplasm. Expression of ...
    • Poblete Durán, Natalia; Prades Pérez, Yara; Vera Otarola, Jorge; Soto Rifo, Ricardo; Valiente Echeverria, Fernando Andres (MDPI AG, 2016)
      After viral infection, host cells respond by mounting an anti-viral stress response in order to create a hostile atmosphere for viral replication, leading to the shut-off of mRNA translation (protein synthesis) and the ...