Browsing by Author "XX677175"

Now showing items 1-14 of 14

    • Clinical parameters and biomarkers for anti-TNF treatment prognosis in rheumatoid arthritis patients 
      Cuchacovich Turteltaub, Miguel; Bueno, Daniel; Carvajal Gavilán, Rodrigo; Bravo, Nicolás; Aguillón Gutiérrez, Juan Carlos; Catalán Martina, Diego; Soto Sáez, Lilian (International League of Associations for Rheumatology (ILAR), 2014)
      Tumor necrosis factor (TNF) plays a pivotal role in the pathogenesis of rheumatoid arthritis (RA). This finding has led to the development of TNF blockers for RA treatment. However, response to these therapies is ...
    • Cortisol levels in atypical depression and chronic fatigue syndrome using hair and saliva specimens 
      Herane Vives, Andrés; De Angel, Valeria; Chalder, Trudie; Soto Sáez, Lilian; Chua, Kia-Chong; Young, Allan H.; Cleare, Anthony (Pergamon-Elsevier, 2016)
    • Cortisol levels in chronic fatigue syndrome and atypical depression measured using hair and saliva specimens 
      Herane Vives, Andrés; Papadopoulos, Andrew; Ángel, Valeria de; Chua, Kia-Chong; Soto Sáez, Lilian; Chalder, Trudie; Young, Allan; Cleare, Anthony (Elsevier, 2020)
    • Effect of interleukin-6 receptor blockade on the balance between regulatory T cells and T helper type 17 ... 
      Pesce Reyes, Bárbara; Soto Sáez, Lilian; Sabugo Siraqyan, María Francisca; Wurmann Kiblisky, Pamela; Cuchacovich Turteltaub, Miguel; López Nitsche, Mercedes; Sotelo, P. H.; Molina Sampayo, María Carmen; Aguillón Gutiérrez, Juan Carlos; Catalán Martina, Diego (2013)
      A new paradigm has emerged relating the pathogenesis of rheumatoid arthritis (RA), focused on the balance between T helper type 17 cells and regulatory T cells (Tregs). In humans, both subpopulations depend on ...
    • Infliximab can induce a prolonged clinical remission and a decrease in thyroid hormonal requirements in a ... 
      Sabugo Siraqyan, María Francisca; Liberman Guendelman, Claudio; Niedmann, Juan Pablo; Soto Sáez, Lilian; Cuchacovich Turteltaub, Miguel (SPRINGER, 2008-04)
      SAPHO syndrome is a rare entity that compromises the skeletal system (arthritis-osteitis) and is associated with various dermatological conditions such as palmoplantaris pustulosis (PPP) and acne. We present the case of a ...
    • Mortality and Adverse Events of Special Interest in Adult Patients with Systemic Lupus Erythematosus Receiving ... 
      Sheikh, Saira; De Toledo, Ricardo Acayaba; Geraldino Pardilla, Laura; Harris, Julia; Kurrasch, Regina; Liu, Andrew; Maksimowicz-McKinnon, Kathleen; Quasny, Holly; Roth, David; Soto Sáez, Lilian; Punwaney, Rajesh (Wiley, 2020)
    • Nuevas armas inmunológicas para la medicina del siglo XXI: Terapia biológica basada en el uso de anticuerpos ... 
      Aguillón Gutiérrez, Juan Carlos; Contreras L., Juan; Dotte G., Andrés; Cruzat C., Andrea; Catalán Martina, Diego; Salazar A., Lorena; Molina S., María Carmen; Guerrero P., Julia; López Nitsche, Mercedes; Soto Sáez, Lilian; Salazar Onfray, Flavio; Cuchacovich Turteltaub, Miguel (Sociedad Médica de Santiago, 2003)
      The fusion of a murine B cell and a myeloma cell generates a hybridoma that produces monoclonal antibody (mAb). These murine mAb induce the HAMA (human anti-mouse antibodies) response. Murine mAb have been modified by ...
    • Papel de los polimorfismos -238 y -308 del promotor del factor de necrosis tumoral alfa en la patogenia y ... 
      Llanos M., Carolina; Soto Sáez, Lilian; Sabugo Siraqyan, María Francisca; Bastías Ch., M. José; Salazar A., Lorena; Aguillón Gutiérrez, Juan Carlos; Cuchacovich Turteltaub, Miguel (Sociedad Médica de Santiago, 2005)
      Rheumatoid arthritis (RA) is a systemic autoimmune disease that affects 0.8% of the world population, it affects the synovial membrane of joints and the clinical presentation encompasses a wide spectrum, ranging from a ...
    • A short protocol using dexamethasone and monophosphoryl lipid A generates tolerogenic dendritic cells that ... 
      García González, Paulina; Morales, Rodrigo; Hoyos, Lorena; Maggi, Jaxaira; Campos, Javier; Pesce Reyes, Bárbara; Gárate, David; Larrondo Lillo, Milton; González González, Rodrigo; Soto Sáez, Lilian; Ramos, Verónica; Tobar, Pía; Molina, María Carmen; Pino Lagos, Karina; Catalán Martina, Diego; Aguillón Gutiérrez, Juan Carlos (BioMed Central, 2013)
      Background: Generation of tolerogenic dendritic cells (TolDCs) for therapy is challenging due to its implications for the design of protocols suitable for clinical applications, which means not only using safe products, ...
    • Systemic vasculitis associated with Fasciola hepatica infection 
      Llanos, Carolina; Soto Sáez, Lilian; Sabugo Siraqyan, María Francisca; Gallegos, I.; Valenzuela Letelier, Omar; Verdaguer, J.; Cuchacovich Turteltaub, Miguel (TAYLOR & FRANCIS AS, 2006-04)
      We report the case of a 50-year-old man who presented with systemic vasculitis associated with Fasciola hepatica infection. The patient presented with severe skin, kidney, spleen, ophthalmic, and neurological compromise. ...
    • The presence of anti-citrullinated protein antibodies (ACPA) does not affect the clinical response to ... 
      Soto Sáez, Lilian; Sabugo Siraqyan, María Francisca; Catalán Martina, Diego; Wurmann Kiblisky, Pamela; Cermenatti, Tomás; Gatica Rossi, Héctor; Aravena, Octavio; Salazar, Lorena; Aguillón Gutiérrez, Juan Carlos; Cuchacovich Turteltaub, Miguel (Springer, 2011)
      The introduction of antitumor necrosis factor (TNF) agents has improved the outcome for many patients with rheumatoid arthritis (RA). To date, the only replicated genetic predictor of anti-TNF response is the −308 G > ...
    • The role of interleukin-6 signalling and its therapeutic blockage in skewing the T cell balance in rheumatoid ... 
      Schinnerling, Katina; Aguillón Gutiérrez, Juan Carlos; Catalán Martina, Diego; Soto Sáez, Lilian (Wiley, 2017)
      Therapeutic blockage of cytokine signalling in autoimmune diseases has improved our understanding of the role of these cytokines in triggering, shaping and perpetuating autoimmune responses. In rheumatoid arthritis (RA), ...
    • Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures ... 
      García González, Paulina; Schinnerling, Katina; Sepúlveda Gutiérrez, Alejandro; Maggi, Jaxaira; Hoyos, Lorena; Morales, Rodrigo; Mehdi, Ahmed; Nel, Hendrik; Soto Sáez, Lilian; Pesce Reyes, Bárbara; Molina Sampayo, María Carmen; Cuchacovich Turteltaub, Miguel; Larrondo Lillo, Milton; Neira, Oscar; Catalán Martina, Diego; Hilkens, Catharien M.; Thomas, Ranjeny; Verdugo Salgado, Ricardo; Aguillón Gutiérrez, Juan Carlos (Frontiers Media, 2016-10-25)
      Tolerogenic dendritic cells (TolDCs) are promising tools for therapy of autoimmune diseases, such as rheumatoid arthritis (RA). Here, we characterize monocyte-derived TolDCs from RA patients modulated with dexamethasone ...
    • Uso de rituximab (anticuerpo monoclonal anti-CD20) en lupus eritematoso sistémico refractario a tratamiento: ... 
      Sabugo Siraqyan, María Francisca; Llanos M., Carolina; Soto Sáez, Lilian; Gutiérrez, Jorge; Cuchacovich Turteltaub, Miguel (Sociedad Médica de Santiago, 2005)
      New therapeutic approaches that include depletion of B cells using rituximab, a chimeric monoclonal antibody directed against the B cell specific antigen CD-20 have been developed for the treatment of systemic lupus ...