Browsing by Author "XX677183"

Now showing items 1-7 of 7

    • Assessing chaperone for Zn, Cu-superoxide dismutase as an indicator of copper deficiency in malnourished children 
      Arredondo Olguín, Miguel; Weisstaub Nuta, Sergio; Medina, Marcos; Suazo Romo, Miriam; Guzmán, Miguel; Araya, Magdalena (Elsevier, 2014)
      It is not clear how frequent is copper deficiency in humans. Current copper markers are not sensitive enough to detect early copper deficiency and new markers are needed. CCS is a candidate to become a copper ...
    • CCS and SOD1 mRNA are reduced after copper supplementation in peripheral mononuclear cells of individuals ... 
      Suazo Romo, Miriam; Olivares, Felipe; Méndez, Marco; Pulgar Tejo, Rodrigo; Prohaska, Joseph R.; Arredondo Olguín, Miguel Armando; Pizarro Aguirre, Fernando; Ordóñez Pizarro, Fernando; Araya, Magdalena; González Canales, Mauricio (ELSEVIER SCIENCE INC, 2008-04)
      The limits of copper homeostatic regulation in humans are not known, making it difficult to define the milder effects of early copper excess. Furthermore, a robust assay to facilitate the detection of early stages of ...
    • Copper Supplementation at 8 mg Neither Affects Circulating Lipids nor Liver Function in Apparently Healthy ... 
      Rojas Sobarzo, Loreto; Olivares Grohnert, Manuel; Brito, Alex; Suazo Romo, Miriam; Araya, Magdalena; Pizarro Aguirre, Fernando (Springer, 2013)
      Copper (Cu) deficiency has been reported to influence lipid metabolism, but the effects in humans are controversial. To evaluate the effects of 8 mg Cu/day supplementation (as copper sulfate) for 6 months on the lipid ...
    • Expression of copper-related genes in response to copper load 
      González Canales, Mauricio; Reyes Jara, Angélica; Suazo Romo, Miriam; Jo, William J.; Vulpe, Chris (AMER SOC CLINICAL NUTRITION, 2008-09-01)
      Copper is an essential micronutrient for all biological systems. Multiple proteins require one or more atoms of copper for proper structure and function, but excess of copper is toxic. To prevent the consequences of copper ...
    • Increased levels of metallothionein in placenta of smokers 
      Ronco Macchiavello, Ana María; Argüello, Graciela; Suazo Romo, Miriam; Llanos Silva, Miguel (ELSEVIER SCI IRELAND LTD, 2005-03-01)
      Experiments were designed to evaluate and compare metallothionein (NIT), zinc and cadmium levels in human placentas of smoking and non-smoking women. Smoking was assessed by self-reported cigarette consumption and urine ...
    • Physiological copper exposure in Jurkat cells induces changes in the expression of genes encoding cholesterol ... 
      Gutiérrez García, Ricardo; Pozo, Talía del; Suazo Romo, Miriam; Cambiazo Ayala, Liliana; González Canales, Mauricio (Springer, 2013)
      Copper is an essential micronutrient that functions as an enzymatic cofactor in a wide range of cellular processes. Although adequate Cu levels are essential for normal metabolism, excess Cu can be toxic to cells. ...
    • Transcriptional activation of glutathione pathways and role of glucose homeostasis during copper imbalance 
      Quiroz, Natalia; Rivas, Nicole; Pozo, Talía del; Burkhead, Jason; Suazo Romo, Miriam; González, Mauricio; Latorre, Mauricio (Springer, 2015)
      Copper is an essential micronutrient for organism health. Dietary changes or pathologies linked to this metal induce changes in intracellular glutathione concentrations. Here, we studied the transcriptional activation of ...