Browsing by Author "a50b4882-2d93-4844-ab9d-ca415f773476"

Now showing items 1-6 of 6

    • A mechanism of male germ cell apoptosis induced by bisphenol-a and nonylphenol involving ADAM17 and p38 ... 
      Urriola-Muñoz, Paulina; Lagos Cabré, Raúl; Moreno, Ricardo D. (Public Library of Science, 2014)
      © 2014 Urriola-Muñoz et al.Germ cell apoptosis regulation is pivotal in order to maintain proper daily sperm production. Several reports have shown that endocrine disruptors such as Bisphenol-A (BPA) and Nonylphenol (NP) ...
    • Apoptosis, necrosis and autophagy are influenced by metabolic energy sources in cultured rat spermatocytes 
      Bustamante Marín, Ximena; Quiroga, Clara; Lavandero González, Sergio; Reyes, Juan G.; Moreno, Ricardo D. (2012)
      Apoptosis, necrosis and autophagy are mechanistically related processes that control tissue homeostasis and cell survival. In the testis, germ cell death is important for controlling sperm output, but it is unknown whether ...
    • Differential localization of α' and β subunits of protein kinase CK2 during rat spermatogenesis 
      Alvarado-Díaz, Carlos P.; Tapia, Julio; Antonelli, Marcelo; Moreno, Ricardo D. (2009)
      Protein kinase CK2 is a serine/threonine kinase expressed in organisms from yeast to human and is composed of a catalytic subunit (α or α') and a regulatory subunit (β) forming a holoenzyme with the possible subunit ...
    • Expression of the ectodomain-releasing protease ADAM17 is directly regulated by the osteosarcoma and ... 
      Araya López, Héctor; Sepulveda, Hugo; Lizama, Carlos O.; Vega Villa, Oscar; Jerez, Sofia; Briceño, Pedro F.; Thaler, Roman; Riester, Scott M.; Antonelli Anativia, Marcelo; Salazar Onfray, Flavio; Rodríguez Vives, Juan Pablo; Moreno, Ricardo D.; Montecino, Martín; Charbonneau, Martine; Dubois, Claire; Galindo Díaz, Mario; Stein, Gary; van Wijnen, Andre (Wiley-Liss Inc., 2018)
      Osteoblast differentiation is controlled by transcription factor RUNX2 which temporally activates or represses several bone-related genes, including those encoding extracellular matrix proteins or factors that control ...
    • Microtubule configuration and its relationship to sperm morphology in mammalian spermiogenesis 
      Moreno, Ricardo D.; Brouwer-Visser, Jurriaan; Alvarado, Carlos P.; Lagos-Cabré, Raúl; Antonelli, Marcelo (2008)
      The acrosome is a secretory vesicle located in the mammalian sperm head. Its main function is to transport hydrolytic enzymes. These enzymes will dissolve the zona pellucid, assisting the sperm in fertilizing the egg. The ...
    • TACE/ADAM17 is involved in germ cell apoptosis during rat spermatogenesis 
      Lizama, Carlos; Rojas-Benítez, Diego; Antonelli, Marcelo; Ludwig, Andreas; Bustamante-Marín, Ximena; Brouwer-Visser, Jurriaan; Moreno, Ricardo D. (2010)
      The pathways leading to male germ cell apoptosis in vivo are poorly understood, but are highly relevant for the comprehension of sperm production regulation by the testis. In this work, we show the evidence of a mechanism ...