Browsing by Author "a55db268-42e7-480f-ac64-734cbafe685f"

Now showing items 1-12 of 12

    • An immunological strategy to monitor in situ the phosphate starvation state in Thiobacillus ferrooxidans 
      Varela, Patricia; Levicán, Gloria; Rivera, Francisco; Jerez, Carlos A. (1998)
      Thiobacillus ferrooxidans is one of the chemolithoautotrophic bacteria important in industrial biomining operations. During the process of ore bioleaching, the microorganisms are subjected to several stressing conditions, ...
    • Causal role of oxidative stress in liver preconditioning by thyroid hormone in rats 
      Fernández Arancibia, Virginia; Tapia Opazo, Gladys; Varela, Patricia; Gaete González, Leonardo; Vera, Gemma; Mora, Catalina; Vial, María T.; Videla Cabrera, Luis (ELSEVIER, 2008-05-01)
      Hepatic ischemia-reperfusion (R) injury, a major clinical drawback during surgery, is abolished by L-3,3',5-triiodothyronine (T-3) administration. Considering that the triggering mechanisms are unknown, the aim of this ...
    • Identification and characterization of GroEL and DnaK homologues in Thiobacillus ferrooxidans 
      Varela, Patricia; Jerez, Carlos A. (1992)
      The major heat shock proteins from Thiobacillus ferrooxidans were identified as DnaK and GroEL equivalents by Western blotting and analysis of the N-terminal amino acid sequence of spots isolated from dried 2-D polyacrylamide ...
    • Involvement of Kupffer cell-dependent signaling in T3-induced hepatocyte proliferation in vivo 
      Fernández, Virginia; Reyes, Solange; Bravo, Sergio; Sepúlveda, Rodrigo; Romanque, Pamela; Santander, Gonzalo; Castillo, Iván; Varela, Patricia; Tapia, Gladys; Videla Cabrera, Luis (2007)
      Thyroid hormone-induced calorigenesis triggers liver oxidative stress with concomitant TNF-α production by Kupffer cells and up-regulation of gene expression. Considering that cyclin-dependent kinase-2 (CDK-2) performs ...
    • Liver preconditioning induced by iron in a rat model of ischemia/reperfusion 
      Galleano, Mónica; Tapia Opazo, Gladys; Puntarulo, Susana; Varela, Patricia; Videla Cabrera, Luis; Fernández Arancibia, Virginia (Elsevier, 2011)
      Aims: Liver preconditioning against ischemia–reperfusion (IR) injury is a major area of experimental research, in which regulation of gene expression with cytoprotective responses due to transient oxidative stress development ...
    • N-3 PUFA supplementation triggers PPAR-α activation and PPAR-α/NF-κB interaction: Anti-inflammatory ... 
      Zúñiga, Jessica; Cancino, Milena; Medina, Fernando; Varela, Patricia; Vargas, Romina; Tapia Opazo, Gladys; Videla Cabrera, Luis; Fernández Arancibia, Virginia (2011)
      Dietary supplementation with the n-3 polyunsaturated fatty acids (n-3 PUFA) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) to rats preconditions the liver against ischemia-reperfusion (IR) injury, with reduction ...
    • Protection against in vivo liver ischemia-reperfusion injury by n-3 long-chain polyunsaturated fatty acids ... 
      Zúñiga, Jessica; Venegas, Francisca; Villarreal, Marcela; Núñez, Daniel; Chandía, Marlene; Valenzuela, Rodrigo; Tapia Opazo, Gladys; Varela, Patricia; Videla Cabrera, Luis; Fernández Arancibia, Virginia (2010)
      N-3 polyunsaturated fatty acids (n-3 PUFA) affect inflammatory processes. This study evaluated the effects of dietary supplementation with fish oil on hepatic ischemia-reperfusion (IR) injury in the rat. Parameters of liver ...
    • Redox regulation of thyroid hormone-induced Kupffer cell-dependent IκB-α phosphorylation in relation to ... 
      Fernández Arancibia, Virginia; Tapia Opazo, Gladys; Varela, Patricia; Videla Cabrera, Luis (2005)
      Thyroid hormone-induced calorigenesis promotes oxidative stress in the liver with higher respiratory burst activity in Kupffer cells, which could increase the expression of redox-sensitive genes. Our aim was to test the ...
    • Redox up-regulated expression of rat liver manganese superoxide dismutase and Bcl-2 by thyroid hormone is ... 
      Fernández Arancibia, Virginia; Tapia Opazo, Gladys; Varela, Patricia; Castillo, Iván; Mora, Catalina; Moya, Francisco; Orellana, Myriam; Videla Cabrera, Luis (2005)
      Recently, we demonstrated that 3,3',5-triiodothyronine (T3) induces oxidative stress in rat liver, with enhancement in the DNA binding of nuclear factor-kappaB (NF-kappaB) and the NF-kappaB-dependent expression of tumor ...
    • Thyroid hormone calorigenesis and mitochondrial redox signaling: Upregulation of gene expression 
      Videla Cabrera, Luis; Fernández Arancibia, Virginia; Tapia Opazo, Gladys; Varela, Patricia (2007)
      Thyroid hormone (TH, T3) is required for the normal function of most tissues, with major effects on O2 consumption and metabolic rate. These are due to transcriptional activation of respiratory genes through the interaction ...
    • Upregulation of liver inducible nitric oxide synthase following thyroid hormone preconditioning: Suppression ... 
      Fernández, Virginia; Tapia, Gladys; Varela, Patricia; Cornejo, Pamela; Videla Cabrera, Luis (2009)
      3,3,5-L-Triiodothyronine (T 3) exerts significant protection against ischemia-reperfusion (IR) liver injury in rats. Considering that the underlying mechanisms are unknown, the aim of this study was to assess the involvement ...
    • Zone i of Tear Microdesiccates Is a Lipid-Containing Structure 
      Traipe, Felipe; Traipe, Leonidas; Salinas Toro, Daniela; López, Daniela; Valenzuela, Felipe; Pérez, Claudio; Cartes, Cristian; Zuazo, Francisca; Varela, Patricia; Toledo Araya, Héctor; López Solís, Remigio (Lippincott Williams and Wilkins, 2017)
      Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. Purpose: Morphological features of tear microdesiccates on glass surfaces have been associated with tear fluid status. Tear-film lipids play a critical role ...