Browsing by Author "a8f566d1-38d3-4003-b06c-13efd43b33dd"

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    • ent-Beyerane Diterpenes as a Key Platform for the Development of ArnT-Mediated Colistin Resistance Inhibitors 
      Quaglio, Deborah; Mangoni, María Luisa; Stefanelli, Roberta; Corradi, Silvia; Casciaro, Bruno; Vergine, Valeria; Lucantoni, Federica; Cavinato, Luca; Cammarone, Silvia; Loffredo, María Rosa; Cappiello, Floriana; Calcaterra, Andrea; Erazo Giuffra, Silvia; Ghirga, Francesca; Mori, Mattia; Imperi, Francesco; Ascenzioni, Fiorentina; Botta, Bruno (American Chemical Society, 2020)
      Colistin is a last-resort antibiotic for the treatment of multidrug resistant Gram-negative bacterial infections. Recently, a natural ent-beyerene diterpene was identified as a promising inhibitor of the enzyme responsible ...