Browsing by Author "aa219a65-b6ee-4be3-b5b7-27dd13a23bdb"

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Artículo

Frequency of the 185delAG mutation in the BRCA1 gene in Chilean healthy women with family history of breast ...

Jara, Lilian; Ampuero Llanos, Sandra; Seccia, Lorena; Bustamante, Mario; Blanco, Rafael; Santibáñez, Eudocia; Reyes, José Miguel; Ojeda, José Manuel (2002)

BACKGROUND: Breast cancer is the most common malignancy among women, and is the second cause of cancer mortality among Chilean women. Female mortality due to breast cancer in Chile has shown a steady increase from 9.5 ...
Artículo

Genetic variants in pre-miR-146a, pre-miR-499, pre-miR-125a, pre-miR-605, and pri-miR-182 are associated ...

Morales, Sebastián; De Mayo, Tomas; Gulppi, Felipe Andrés; González Hormazábal, Patricio; Carrasco, Valentina; Reyes, José Miguel; Gómez, Fernando; Waugh, Enrique; Jara, Lilian (MDPI AG, 2018)

© 2018 by the authors. Licensee MDPI, Basel, Switzerland. Breast cancer (BC) is one of the most frequent tumors affecting women worldwide. microRNAs (miRNAs) single-nucleotide polymorphisms (SNPs) likely contribute to BC ...
Artículo

Germline variants in driver genes of breast cancer and their association with familial and early-onset ...

Fernández Moya, Alejandro; Morales, Sebastián; Arancibia, Trinidad; González Hormazábal, Patricio; Tapia, Julio; Godoy Herrera, Raúl; Reyes, José Miguel; Gómez, Fernando; Waugh, Enrique; Jara Sosa, Lilian (MDPI, 2020)

The genetic variations responsible for tumorigenesis are called driver mutations. In breast cancer (BC), two studies have demonstrated that germline mutations in driver genes linked to sporadic tumors may also influence ...
Artículo

Molecular analysis of the eighteen most frequent mutations in the BRCA 1 gene in 63 Chilean breast cancer families

Jara, Lilian; Ampuero Llanos, Sandra; Santibáñez, Eudocia; Seccia, Lorena; Rodríguez, Juan; Bustamante, Mario; Lay-Son, Guillermo; Ojeda, José Manuel; Reyes, José Miguel; Blanco, Rafael (Society of Biology of Chile, 2004)

BRCA1 gene mutations account for nearly all families with multiple cases of both early onset breast and/or ovarian cancer and about 30% of hereditary breast cancer. Although to date more than 1,237 distinct mutations, ...
Artículo

Multiple primary malignant neoplasms detected by PET/CT in cancer patients Cáncer sincrónico y metacrónico ...

Ladrón De Guevara, David; Quera, Rodrigo; Rozas, Sebastián; Schacher, Shmuel; Reyes, José Miguel; Pardo, Claudio; Pefaur, Raúl (Sociedad Medica de Santiago, 2017)

© 2018, Sociedad Medica de Santiago. All rights reserved. Background: Imaging with F18-fluorodeoxyglucose PET/CT is used to determine sites of abnormal glucose metabolism and can be used to characterize and localize many ...