Browsing by Author "ac988ff9-5ce8-4813-83d0-f367d3d4a3af"

Now showing items 1-11 of 11

    • Age-dependent increases in apoptosis/necrosis ratios in human lymphocytes exposed to oxidative stress 
      Behrens Pellegrino, María Isabel; Silva, Monica; Schmied, Astrid; Salech Morales, Felipe; Manzur, Hachi; Rebolledo, Rolando; Bull Simpfendorfer, Ricardo; Torres, Vicente; Henríquez, Mauricio; Quest, Andrew F. G. (2011)
      Unlike apoptosis, mechanisms leading to necrosis are less well understood. Moreover, changes in necrosis as a function of age have not been studied in human lymphocytes. H 2O 2-induced death of peripheral lymphocytes (56 ...
    • Consolidated framework for advancing implementation science for the implementation process and adherence ... 
      Garrido Montenegro, Maricel; Álvarez Espinoza, Evelyn; Ponce, Daniela P.; Salech Morales, Felipe; Tobar, Daniel I.; Tobar Almonacid, Eduardo (Wiley, 2020)
      Objective To evaluate the contribution of applying the theoretical framework of implementation science for adherence to non-pharmacological interventions to prevent delirium. Methods A quasi-experimental prospective design ...
    • Fall prevention in community-dwelling older adults 
      Kirk, Ben; Salech Morales, Felipe; Duque, Gustavo (Massachusetts Medical Society, 2020)
    • Frizzled-1 receptor regulates adult hippocampal neurogenesis 
      Mardones, Muriel D.; Andaur, Gabriela A.; Varas Godoy, Manuel; Henriquez, Jenny F.; Salech Morales, Felipe; Behrens Pellegrino, María Isabel; Couve Correa, Andrés; Inestrosa, Nibaldo C.; Varela Nallar, Lorena (BioMed Central Ltd., 2016)
      © 2016 Mardones et al. Background: In the adult hippocampus new neurons are continuously generated from neural stem cells (NSCs) present at the subgranular zone of the dentate gyrus. This process is controlled by Wnt ...
    • Increased susceptibility to oxidative death of lymphocytes from Alzheimer patients correlates with dementia ... 
      Ponce, Daniela P.; Salech Morales, Felipe; San Martín Rovirosa, Carol; Silva, Monica; Xiong, Chengjie; Roe, Catherine M.; Henríquez, Mauricio; Quest, Andrew F. G.; Behrens Pellegrino, María Isabel (Bentham Science Publishers B.V., 2014)
      © 2014 Bentham Science Publishers.We previously reported on enhanced susceptibility to death of lymphocytes from Alzheimer’s disease (AD) patients when exposed to hydrogen peroxide (H2O2)-induced oxidative stress and an ...
    • Inverse relationship between alzheimer's disease and cancer: How immune checkpoints might explain the ... 
      Rogers Castillo, Nicole K.; Romero, César A.; San Martín Rovirosa, Carol D.; Ponce, Daniela P.; Salech Morales, Felipe; López, Mercedes N; Gleisner, Alejandra; Tempio Sepúlveda, Fabián; Behrens Pellegrino, María I. (IOS Press, 2020)
      Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the adult population. There is evidence of an inverse epidemiological relationship between AD and cancer, another prevalent age-related disease. ...
    • Inverse susceptibility to oxidative death of lymphocytes obtained from Alzheimer's patients and skin cancer ... 
      Behrens Pellegrino, María Isabel; Silva, Monica; Salech Morales, Felipe; Ponce, Daniela P.; Merino, Daniela; Sinning, Mariana; Xiong, Chengjie; Roe, Catherine M.; Quest, Andrew F. G. (2012)
      A paucity of cancer in individuals with Alzheimer's disease (AD) and low rates of AD in cancer survivors has been reported in epidemiological studies. Deregulation in opposite directions of biological mechanisms, such as ...
    • Mobile ECMO in COVID-19 patient: case report 
      Martínez, Daniela; Salech Morales, Felipe; Sint Jan Van, Nicolette; Regueira, Tomás; Villalabeitia, Eli; Rufs, Jorge; Fajardo, Christian; Castillo, Roberto; Iñiguez, José; Durán, Luisa; Díaz, Rodrígo (Springer, 2020)
      At July 25, 2020, WHO had recorded more than 16.1 million confirmed COVID-19 cases, 1% of them developed critical illness. These patients can experience rapid progression to profound hypoxemia and severe acute respiratory ...
    • PARP-1 and p53 regulate the increased susceptibility to oxidative death of lymphocytes from MCI and AD patients 
      Salech Morales, Felipe; Ponce, Daniela P.; San Martín Rovirosa, Carol; Rogers Castillo, Nicole; Chacón, Carlos; Henriquez Luna, Mauricio; Behrens Pellegrino, María Isabel (Frontiers media SA, 2017)
      Mild cognitive impairment (MCI) is a clinically detectable initial stage of cognitive deterioration with a high conversion rate to dementia. There is increasing evidence that some of the cerebral alterations present in ...
    • Tumor-induced osteomalacia: experience from a South American academic center 
      González, G.; Baudrand, R.; Sepúlveda, M. F.; Vucetich, N.; Guarda, F. J.; Villanueva, P.; Contreras, O.; Villa, A.; Salech Morales, Felipe; Toro Cabrera, Luis; Michea Acevedo, Luis; Florenzano, P. (Springer, 2017)
      The majority of tumor-induced osteomalacia cases have been reported in the Northern Hemisphere and Asia. In this first series of South American patients, we show that the clinical presentation and sensitivity of plasmatic ...
    • Vitamin D increases A beta 140 Plasma levels and protects Lymphocytes from oxidative death in mild cognitive ... 
      San Martín Rovirosa, Carol; Henriquez Luna, Mauricio; Chacon, Carlos; Ponce, Daniela P.; Salech Morales, Felipe; Rogers Castillo, Nicole; Behrens Pellegrino, María Isabel (2018)
      Background: Mild cognitive impairment (MCI) has an increased rate of progression to dementia. Alterations of some metabolic factors, such as deficiency of vitamin D, are a risk factor for cognitive deterioration. Vitamin ...