Browsing by Author "aebae36e-5016-4f1f-b4de-2f98de20e8e3"

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    • Melatonin decreases pulmonary vascular remodeling and oxygen sensitivity in pulmonary hypertensive newborn lambs 
      Astorga, Cristian R.; González Candia, Alejandro; Figueroa, Esteban G.; Cañas, Daniel; Ebensperger Darrouy, Germán; Reyes Catalán, Víctor; Llanos Mansilla, Jorge; Herrera Videla, Emilio; Candia, Alejandro A. (Frontiers media SA, 2018)
      Background: Chronic hypoxia and oxidative stress during gestation lead to pulmonary hypertension of the neonate (PHN), a condition characterized by abnormal pulmonary arterial reactivity and remodeling. Melatonin has strong ...
    • Melatonin long-lasting beneficial effects on pulmonary vascular reactivity and redox balance in chronic ... 
      González Candia, Alejandro; Candia, Alejandro A.; Figueroa, Esteban G.; Feixes, Elisenda; González Candia, Cristopher; Aguilar, Simón A.; Ebensperger, Germán; Reyes, Roberto V.; Llanos, Aníbal J.; Herrera, Emilio A. (Wiley, 2020)
      Pulmonary arterial hypertension of the neonate (PAHN) is a pathophysiological condition characterized by maladaptive pulmonary vascular remodeling and abnormal contractile reactivity. This is a multifactorial syndrome ...