Browsing by Author "af03c448-b985-49e6-995a-ba0dbeede49f"

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    • Prolonged AT(1)R activation induces Ca(V)1.2 channel internalization in rat cardiomyocytes 
      Hermosilla, Tamara; Encina, Matías; Morales, Danna; Moreno, Cristian; Conejeros, Carolina; Alfaro Valdés, Hilda M.; Lagos Meza, Felipe; Simon, Felipe; Altier, Christophe; Varela, Diego (Nature Publishing Group, 2017)
      The cardiac L-type calcium channel is a multi-subunit complex that requires co-assembling of the pore-forming subunit Ca(V)1.2 with auxiliary subunits Ca-V alpha 2 delta and Ca-V beta. Its traffic has been shown to be ...
    • TRPM7 mediates kidney injury, endothelial hyperpermeability and mortality during endotoxemia 
      Gatica, Sebastián; Villegas, Vicente; Vallejos, Alejandro; Olivares, Pedro; Aballai, Víctor; Lagos Meza, Felipe; Echeverría, César; Cabello Verrugio, Claudio; Varela Lekanda, Diego; Simón, Felipe (Nature Publishing Group, 2020)
      Acute kidney injury and endothelial hyperpermeability are main features observed during severe sepsis with low survival rate. Transient receptor potential melastatin 7 (TRPM7) calcium channel inhibition protects against ...