Browsing by Author "b1ae4e5b-16f6-43ac-891d-c9569f8b815d"

Now showing items 1-3 of 3

    • Inflammation: A major target for compounds to control Alzheimer's Disease 
      Maccioni Baraona, Ricardo; Navarrete, Leonardo P.; González, Andrea; González Canacer, Alejandra; Guzmán Martínez, Leonardo; Cortes, Nicole (IOS Press, 2020)
      Several hypotheses have been postulated to explain how Alzheimer's disease is triggered, but none of them provide a unified view of its pathogenesis. The dominant hypothesis based on build-ups of the amyloid-beta peptide ...
    • Neuroimmune tau mechanisms: their role in the progression of neuronal degeneration 
      Cortes, Nicole; Andrade, Victor; Guzmán Martínez, Leonardo; Estrella, Matías; Maccioni Baraona, Ricardo (MDPI, 2018-04)
      Progressive neurodegenerative pathologies in aged populations are an issue of major concern worldwide. The microtubule-associated protein tau is able to self-aggregate to form abnormal supramolecular structures that include ...
    • Plasma Tau Variants Detected by a Novel Anti-Tau Monoclonal Antibody: A Potential Biomarker for Alzheimer’s Disease 
      González, Andrea; Guzmán Martínez, Leonardo; Maccioni Baraona, Ricardo (IOP Publishing, 2020)
      Background: A major drawback in Alzheimer's disease (AD) is the lack of validated biomarkers for routine clinical diagnostic. We have reported earlier a novel blood biomarker, named Alz-tau (R), based on variants of platelet ...