Browsing by Author "bbe019ad-a0a9-40fc-a49a-8e1c01fcd5a5"

Now showing items 1-4 of 4

    • ACE2 and vasoactive peptides: Novel players in cardiovascular/renal remodeling and hypertension 
      Mendoza Torres, Evelyn; Oyarzún, Alejandra; Mondaca Ruff, David; Azocar, Andrés; Chiong Lay, Mario; Castro, Pablo F.; Jalil Milad, Jorge; Lavandero González, Sergio; Ocaranza, María Paz (2015)
      The renin–angiotensin system (RAS) is a key component of cardiovascular physiology and homeostasis due to its influence on the regulation of electrolyte balance, blood pressure, vascular tone and cardiovascular remodeling. ...
    • The STIM1 inhibitor ML9 disrupts basal autophagy in cardiomyocytes by decreasing lysosome content 
      Shaikh, S.; Troncoso Cotal, Rodrigo; Mondaca Ruff, David; Parra Ortíz, María Valentina; García Nannig, Lorena; Chiong Lay, Mario; Lavandero González, Sergio (Elsevier, 2018)
      Stromal-interaction molecule 1 (STIM1)-mediated store-operated Ca2+ entry (SOCE) plays a key role in mediating cardiomyocyte hypertrophy, both in vitro and in vivo. Moreover, there is growing support for the contribution ...
    • Therapeutic targeting of autophagy in myocardial infarction and heart failure 
      Riquelme, Jaime A.; Chávez, Myra N.; Mondaca Ruff, David; Bustamante, Mario; Vicencio, José M.; Quest, Andrew F. G.; Lavandero González, Sergio (Taylor & Francis, 2016)
      Introduction: Myocardial infarction (MI) is the leading cause of death. When MI is not lethal, heart failure (HF) is a major consequence with high prevalence and poor prognosis. The targeting of autophagy represents a ...
    • Transforming growth factor-beta and Forkhead box O transcription factors as cardiac fibroblast regulators 
      Norambuena Soto, Ignacio; Núñez Soto, Constanza; Sanhueza Olivares, Fernanda; Cancino Arenas, Nicole; Mondaca Ruff, David; Vivar Sánchez, Raúl; Díaz Araya, Guillermo; Mellado, Rosemarie; Chiong Lay, Mario (IRCA-BSSA, 2017)
      Fibroblasts play several homeostatic roles, including electrical coupling, paracrine signaling and tissue repair after injury. Fibroblasts have low secretory activity. However, in response to injury, they differentiate to ...