Browsing by Author "c123e7be-85ff-41a7-a1fb-2eab579785d8"

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    • Development of murine lupus involves the combined genetic contribution of the SLAM and FcγR intervals within ... 
      Jørgensen, Trine N.; Alfaro, Jennifer; Enriquez, Hilda L.; Jiang, Chao; Loo, William M.; Atencio, Stephanie; Gubbels Bupp, Melanie R.; Mailloux, Christina M.; Metzger, Troy; Flannery, Shannon; Rozzo, Stephen J.; Kotzin, Brian L.; Rosemblatt Silber, Mario César; Bono Merino, María Rosa; (2010)
      Autoantibodies are of central importance in the pathogenesis of Ab-mediated autoimmune disorders. The murine lupus susceptibility locus Nba2 on chromosome 1 and the syntenic human locus are associated with a loss of immune ...
    • Ligand-dependent structural changes and limited proteolysis of Escherichia coli phosphofructokinase-2 
      Cabrera Paucar, Ricardo; Guixé Leguía, Victoria Cristina; Alfaro, Jennifer; Rodríguez, Patricio H.; Babul Cattán, Jorge (2002)
      Binding of MgATPto the allosteric site of phosphofructokinase-2 promotes a dimer to tetramer conversion. In the presence of Fru-6-Pthe enzyme remains as a dimer. Limited proteolysis in the presence of MgATPcompletely ...