Now showing items 1-19 of 19

    • Lombardo, Mary-Jane; Michalski, Jane; Martínez Wilson, Héctor; Morín, Cara; Hilton, Tamara; Morín, Cara; Hilton, Tamara; Osorio Abarzúa, Carlos Gonzalo; Nataro, James P.; Tacket, Carol O.; Camilli, Andrew; Kaper, James B. (National Academy of Sciences of the USA, 2007)
      In vivo expression technology (IVET) has been widely used to study gene expression of human bacterial pathogens in animal models, but has heretofore not been used in humans to our knowledge. As part of ongoing efforts to ...
    • Ulloa Flores, María Teresa; Porte T., Lorena; Braun J., Stephanie; Dabanch P., Jeannette; Fica Cubillos, Alberto; Henríquez A., Tania; Osorio Abarzúa, Carlos Gonzalo (Sociedad Chilena de Infectología, 2011)
      Pathogenic Vibrio cholerae isolates, the etiologic agents of cholera, generally express one of two O antigens (O1 or O139). Most environmental isolates are nonpathogenic and are referred to as “non-O1, non-O139”. However some ...
    • Osorio Abarzúa, Carlos Gonzalo (Sociedad Chilena de Infectología, 2015)
      The first Chair of Microbiology in Chile was created in the School of Medicine of the Cañadilla at the University of Chile in 1892. Dr. Alejandro del Río Soto Aguilar was its first Professor. For almost three decades it ...
    • Osorio Abarzúa, Carlos Gonzalo (Sociedad Médica de Santiago, 2013)
      The building of the Cañadilla School of Medicine of the University of Chile, inaugurated during the government of President Jose Manuel Balmaceda Fernández (1886-1891), was located northern to the men´s section of the ...
    • Osorio Abarzúa, Carlos Gonzalo (Soc Médica Santiago, 2016)
      This work describes the origin of the different locations that Casa de Orates (Madhouse) has occupied in Chile. The locations of this institution at the Yungay and Chimba neighborhoods area are specially analyzed. Moreover, ...
    • Núñez, Harold; Ulloa Flores, María Teresa; Guerra, Fabiola; Osorio Abarzúa, Carlos Gonzalo (Sociedad Médica de Santiago, 2009)
      Background: Most clinical isolates of Vibrio parahaemolyticus produce a major virulence factor known as the thermostable direct hemolysin (TDH). TDH is encoded by the tdh gene which is located in a genomic pathogenicity ...
    • Ortiz Zúñiga, Sylvia; Osorio Abarzúa, Carlos Gonzalo; Solari Illescas, Aldo (Elsevier, 2017-07)
      The taxon Trypanosoma cruzi, causative agent of Chagas disease, is composed of several discrete typing units (DTUs) named TcI-TcVI, and Tcbat. The history of the taxon T. cruzi is known, even though several controversial ...
    • Ortiz Zúñiga, Sylvia; Osorio Abarzúa, Carlos Gonzalo; Solari Illescas, Aldo (Elsevier, 2017)
      The taxon Trypanosoma cruzi, causative agent of Chagas disease, is composed of several discrete typing units (DTUs) named TcI-TcVI, and Tcbat. The history of the taxon T. cruzi is known, even though several controversial aspects ...
    • Osorio Abarzúa, Carlos Gonzalo (Sociedad Chilena de Infectología, 2018)
      The historical development of the terms “infection” and “miasma” is analyzed. Miasma was understood as a kind of corrupt or pestilent air that emanated from putrefactive bodies and spread infectious diseases. This concept ...
    • Elola-López, Ana; Esquivel, María José; Muñoz Bergmann, Cristian; Beltrán, Sebastián; Osorio Abarzúa, Carlos Gonzalo; Trombert, Annette N. (iMed publ., 2015)
      Virulent and non-virulent Vibrio parahaemolyticus (V. parahaemolyticus) strains coexist together in seawater. A PCR–restriction fragment length polymorphism (PCR-RFLP) technique could differentiate between clinical ...
    • García, Lineth; Ortiz Zúñiga, Sylvia; Osorio Abarzúa, Carlos Gonzalo; Cruz Torrico, Mary; Torrico, Faustino; Solari Illescas, Aldo (Plos One, 2012)
      The aim of this study was to establish the phylogenetic relationships of trypanosomes present in blood samples of Bolivian Carollia bats. Eighteen cloned stocks were isolated from 115 bats belonging to Carollia perspicillata ...
    • O'Ryan Gallardo, Miguel; Peña, Alfredo; Vergara, Rodrigo; Díaz, Janepsy; Mamani Manzano, Nora; Cortés, Héctor; Lucero Álvarez, Yalda; Vidal Álvarez, Roberto; Osorio Abarzúa, Carlos Gonzalo; Santolaya de Pablo, María Elena; Hermosilla Díaz, Germán; Prado Jiménez, Valeria (Lippincott Williams, 2010)
      Rotavirus and more recently noroviruses are recognized as main causes of moderate to severe acute diarrhea episodes (ADE) in children < or =5 years of age. Comparing epidemiologic and clinical features of norovirus to ...
    • O'Ryan Gallardo, Miguel; Hermosilla Díaz, Germán; Osorio Abarzúa, Carlos Gonzalo (Lippincott Williams, 2009)
      The authors discuss the most relevant information in the field of rotavirus vaccines published from October 2007 to June 2009; new information on the virus, host response and disease burden that relate to our understanding ...
    • Osorio Abarzúa, Carlos Gonzalo; Crawford, J. A.; Michalski, J.; Martínez Wilson, H.; Kaper, J. B.; Camilli, A. (American Society for Microbiology, 2005)
      We have constructed an improved recombination-based in vivo expression technology (RIVET) and used it as a screening method to identify Vibrio cholerae genes that are transcriptionally induced during infection of infant ...
    • Briceño L., Isabel; Puebla A., Claudio; Guerra A., Francisco; Jensen F., Daniela; Núñez B., Harold; Ulloa Flores, María Teresa; Osorio Abarzúa, Carlos Gonzalo (Sociedad Médica de Santiago, 2009)
      We report a 70-year-old woman, who had recently consumed shellfish, that was admitted to the intensive care unit with septic shock and died 19 hours later due to a multi-organic failure. Microbiological, serological and ...
    • Osorio Abarzúa, Carlos Gonzalo (Sociedad Chilena de Infectología, 2007)
      By definition, zoophytes are organisms with characteristics which are intermediate between plants and animals. The concept is already outlined by Aristotle in his Historia Animalium. In the XVIII century, the great Swedish ...
    • Osorio Abarzúa, Carlos Gonzalo (Sociedad Médica de Santiago, 2010-07)
      The origin of Bacteriology in Chile is intimately bound to the life of the physicians Vicente Izquierdo Sanfuentes and Francisco Puelma Tupper. Both were awarded in 1874 with a government fellowship to study in the most ...
    • Osorio Abarzúa, Carlos Gonzalo; Martínez Wilson, Héctor; Camilli, Andrew (American Society for Microbiology, 2004)
      We made single and combined mutations in ompU, ompT, and the two putative porin genes vca1008 and vc0972. The fitness of the strains was tested in vitro and in the infant mouse model of intestinal infection. We also ...
    • Riquelme Neira, Roberto; Rivera, Alejandra; Sáez, Darwin; Fernández, Pablo; Osorio Abarzúa, Carlos Gonzalo; Del Canto Fuentes, Felipe; Salazar Garrido, Juan; Vidal Álvarez, Roberto; Oñate, Ángel (Frontiers Media, 2016)
      Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is the predominant causative agent of hemorrhagic colitis in humans and is the cause of haemolytic uraemic syndrome and other illnesses. Cattle have been implicated as ...