Browsing by Author "c814db91-8838-4f72-a714-a86f2c310301"

Now showing items 1-6 of 6

    • Anti-TNF therapy in patients with rheumatoid arthritis decreases Th1 and Th17 cell populations and expands ... 
      Aravena, Octavio; Pesce Reyes, Bárbara; Soto, Lilian; Orrego, Natalia; Sabugo, Francisca; Wurmann, Pamela; Molina, María Carmen; Alfaro, Jorge; Cuchacovich Turteltaub, Miguel; Aguillón Gutiérrez, Juan Carlos; Catalán Martina, Diego (2011)
      The aim of this work was to study the effect of anti-TNF treatment on CD4+ Th1, Th17 and regulatory T cells (Tregs), together with CD8+ T cells and NK cells from rheumatoid arthritis (RA) patients. For this purpose, 18 RA ...
    • Development of a new promoter to avoid the silencing of genes in the production of recombinant antibodies ... 
      Zúñiga, Roberto A.; Gutiérrez-González, Matías; Collazo, Norberto; Sotelo, Pablo Hérnan; Ribeiro, Carolina H.; Altamirano, Claudia; Lorenzo, Carmen; Aguillón, Juan Carlos; Molina, María Carmen (BioMed Central Ltd., 2019)
      Background: The production of recombinant proteins in mammalian cell lines is one of the most important areas in biopharmaceutical industry. Viral transcriptional promoters are widely used to express recombinant proteins ...
    • Recognition of an immunogenetically selected Trypanosoma cruzi antigen by seropositive chagasic human sera 
      Aguillón Gutiérrez, Juan Carlos; Harris, Robert; Molina, María Carmen; Colombo, Alicia; Cortés, Claudio; Hermosilla, Tamara; Carreño, Paz; Örn, Anders; Ferreira, Arturo (1997)
      If the H-2 congenic mouse strains A.SW (H-2(s)) and A.CA (H-2(f)), are infected with Trypanosoma cruzi, a 45 kDa protein (Tc45), present in cultured epimastigotes and blood trypomastigotes, is recognized only by the A.SW ...
    • Regulation of tolerogenic features on dexamethasone-modulated MPLA-activated dendritic cells by Myc 
      García González, Paulina; Maggi, Jaxaira; Schinnerling, Katina; Sepúlveda Gutiérrez, Alejandro; Soto, Lilian; Neira, Oscar; Mehdi, Ahmed M.; Nel, Hendrik J.; Pesce, Bárbara; Aravena, Octavio; Molina, María Carmen; Catalán, Diego; Thomas, Ranjeny; Verdugo Salgado, Ricardo (Frontiers Media S.A., 2019)
      Copyright © 2019 García-González, Maggi, Schinnerling, Sepúlveda-Gutiérrez, Soto, Neira, Mehdi, Nel, Pesce, Aravena, Molina, Catalán, Thomas, Verdugo and Aguillón.The potential of tolerogenic dendritic cells (tolDCs) to ...
    • Transcription factor engineering in CHO cells for recombinant protein production 
      Gutiérrez-González, Matías; Latorre, Yesenia; Zúñiga, Roberto; Aguillón, Juan Carlos; Molina, María Carmen; Altamirano, Claudia (Taylor and Francis Ltd, 2019)
      The continuous increase of approved biopharmaceutical products drives the development of more efficient recombinant protein expression systems. Chinese hamster ovary (CHO) cells are the mainstay for this purpose but have ...
    • Trypanosoma cruzi calreticulin: A possible role in Chagas' disease autoimmunity 
      Ribeiro, Carolina Hager; López, Nandy C.; Ramírez, Galia A.; Valck, Carolina E.; Molina, María Carmen; Aguilar, Lorena; Rodríguez, Margarita; Maldonado, Ismael; Martínez, Ramón; González, Carlos; Troncoso, Rodrigo; Lavandero González, Sergio; Gingras, Alexandre R.; Schwaeble, Wilhelm (2009)
      Trypanosoma cruzi (T. cruzi) is the causative agent of Chagas' disease, an endemic and chronic illness that affects 18 million people in Latin America. The mechanisms underlying its pathogenesis are controversial. There ...