Browsing by Author "c8810959-87ed-4d82-a4c9-9f8a9304d6ce"

Now showing items 1-3 of 3

    • FoxO1-Dio2 signaling axis governs cardiomyocyte thyroid hormone metabolism and hypertrophic growth 
      Ferdous, Anwarul; Wang, Zhao V.; Luo, Yuxuan; Li, Dan L.; Luo, Xiang; Schiattarella, Gabriele G.; Altamirano, Francisco; May, Herman I.; Battiprolu, Pavan K.; Nguyen, Annie; Rothermel, Beverly A.; Lavandero González, Sergio; Gillette, Thomas G.; Hill, Joseph A. (Nature, 2020)
      Forkhead box O (FoxO) proteins and thyroid hormone (TH) have well established roles in cardiovascular morphogenesis and remodeling. However, specific role(s) of individual FoxO family members in stress-induced growth and ...
    • Metabolic stress - Induced activation of FoxO1 triggers diabetic cardiomyopathy in mice 
      Battiprolu, Pavan K.; Hojayev, Berdymammet; Jiang, Nan; Wang, Zhao V.; Luo, Xiang; Iglewski, Myriam; Shelton, John M.; Gerard, Robert D.; Rothermel, Beverly A.; Gillette, Thomas G.; Lavandero González, Sergio; Hill, Joseph A. (2012)
      The leading cause of death in diabetic patients is cardiovascular disease; diabetic cardiomyopathy is typified by alterations in cardiac morphology and function, independent of hypertension or coronary disease. However, ...
    • Polycystin-2-dependent control of cardiomyocyte autophagy 
      Criollo Céspedes, Alfredo; Altamirano, Francisco; Pedrozo Cibils, Zully; Schiattarella, Gabriele G.; Li, Dan L.; Rivera‐Mejias, Pablo; Sotomayor Flores, Cristian; Parra, Valentina; Villalobos, Elisa; Battiprolu, Pavan K.; Jiang, Nan; May, Herman I.; Morselli, Eugenia; Somlo, Stefan; Smedt, Humbert de; Gillette, Thomas G.; Lavandero González, Sergio; Hill, Joseph A. (Elsevier, 2018-05)
      Aims: Considerable evidence points to critical roles of intracellular Ca2+ homeostasis in the modulation and control of autophagic activity. Yet, underlying molecular mechanisms remain unknown. Mutations in the gene (pkd2) ...