Browsing by Author "c9fef219-69e6-48a4-89e9-f0f69b264431"

Now showing items 1-4 of 4

    • Epithelial-mesenchymal transition and microRNAs in colorectal cancer chemoresistance to FOLFOX 
      Escalante Escalante, Paula; Quiñones, Luis Abel; Contreras, Héctor R. (MDPI, 2021)
      The FOLFOX scheme, based on the association of 5-fluorouracil and oxaliplatin, is the most frequently indicated chemotherapy scheme for patients diagnosed with metastatic colorectal cancer. Nevertheless, development of ...
    • Genetic polymorphisms as non-modifiable susceptibility factors to laryngeal cancer 
      Escalante, Paula; Barría, Tamara; Cancino Castañeda, Miguel; Rahal Espejo, Maritza; Cerpa, Leslie; Sandoval, Christopher; Molina Mellico, Sebastián; Suárez, Marcelo I.; Martínez, Matías; Cáceres Lillo, Dante; Quiñones, Luis Abel; Varela Figueroa, Nelson (Portland Press, 2020)
      Laryngeal squamous cell carcinoma (LSCC) is a highly disabling disease to the patient, affecting speech, swallowing and respiratory skills. Smoking and alcohol abuse are principal risk factors linked to this disease. Genetic ...
    • Pharmacogenomics, biomarker network, and allele frequencies in colorectal cancer 
      López Cortes, Andrés; Paz y Miño, César; Guerrero, Santiago; Jaramillo Koupermann, Gabriela; León Cáceres, Ángela; Intriago Baldeón, Damaris P.; García Cárdenas, Jennyfer M.; Guevara Ramírez, Patricia; Armendariz Castillo, Isaac; Leone, Paola E.; Quiñones, Luis Abel; Cayún, Juan Pablo; Soria, Néstor W. (Nature, 2020)
      Colorectal cancer is one of the leading causes of cancer death worldwide. Over the last decades, several studies have shown that tumor-related genomic alterations predict tumor prognosis, drug response, and toxicity. These ...
    • Study of the allelic variants CYP2C9*2 and CYP2C9*3 in the Peruvian mestizo population Estudio de las ... 
      Alvarado, Ángel Tito; Muñoz, Ana María; Loja, Berta; Miyasato, Jessica Michiko; García, Jorge Antonio; Cerro, Roberto Andrés; Quiñones, Luis Abel; Varela, Nelson Miguel (Instituto Nacional de Salud, 2019)
      Introduction: CYP2C9 metabolizes approximately 15% of the prescribed drugs. Its gene has alleles whose frequencies differ between ethnic groups and populations. The alleles CYP2C9*2 and CYP2C9*3, account for an enzyme with ...