Browsing by Author "ca107941-ed21-4003-aff4-62853b2b4bcb"

Now showing items 1-3 of 3

    • Dexamethasone-induced muscular atrophy is mediated by functional expression of connexin-based hemichannels 
      Cea Pisani, Luis; Balboa, Elisa; Puebla, Carlos; Vargas, Aníbal; Cisterna, Bruno; Escamilla, Rosalba; Regueira, Tomás; Sáez, Juan C. (Elsevier, 2016)
      Long-term treatment with high glucocorticoid doses induces skeletal muscle atrophy. However, the molecular mechanism of such atrophy remains unclear. We evaluated the possible involvement of connexin-based hemichannels (Cx ...
    • Fast skeletal myofibers of mdx mouse, model of Duchenne muscular dystrophy, express connexin hemichannels ... 
      Cea Pisani, Luis Andrés; Puebla, Carlos; Cisterna, Bruno A.; Escamilla, Rosalba; Vargas, Anibal A.; Frank, Marina; Martinez Montero, Paloma; Prior, Carmen; Molano, Jesus; Esteban Rodríguez, Isabel; Pascual, Ignacio; Gallano, Pía; Lorenzo, Gustavo; Pian, Héctor; Barrio, Luis C.; Willecke, Kla; Saez, Juan C. (Springer, 2016)
      Skeletal muscles of patients with Duchenne muscular dystrophy (DMD) show numerous alterations including inflammation, apoptosis, and necrosis of myofibers. However, the molecular mechanism that explains these changes remains ...
    • Role of Akt and Ca2+ on cell permeabilization via connexin43 hemichannels induced by metabolic inhibition 
      Salas, Daniela; Puebla, Carlos; Lampe, Paul D.; Lavandero González, Sergio; Sáez, Juan Carlos (Elsevier, 2015)
      © 2015 Elsevier B.V. Connexin hemichannels are regulated under physiological and pathological conditions. Metabolic inhibition, a model of ischemia, promotes surface hemichannel activation associated, in part, with increased ...