Now showing items 1-17 of 17

    • Israel Jacard, Yedy; Karahanian, Eduardo; Ezquer, Fernando; Morales, Paola; Ezquer, Marcelo; Rivera Meza, Mario; Herrera-Marschitz Muller, Mario; Quintanilla González, María Elena (Frontiers Media S.A., 2017)
      © 2017 Israel, Karahanian, Ezquer, Morales, Ezquer, Rivera-Meza, Herrera-Marschitz and Quintanilla. This review article addresses the biological factors that influence: (i) the acquisition of alcohol intake; (ii) the ...
    • Ezquer, Fernando; Quintanilla González, María Elena; Morales, Paola; Ezquer, Marcelo; Lespay Rebolledo, Carolyne; Herrera Marschitz, Mario; Israel Jacard, Yedy (Blackwell Publishing Ltd, 2019)
      © 2017 Society for the Study of Addiction Neuroinflammation has been reported to follow chronic ethanol intake and may perpetuate alcohol consumption. Present studies determined the effect of human mesenchymal stem cells ...
    • Quintanilla González, María Elena; Morales, Paola; Ezquer, Fernando; Ezquer, Marcelo; Herrera-Marschitz Muller, Mario; Israel Jacard, Yedy (Blackwell Publishing Ltd, 2018)
      © 2018 by the Research Society on Alcoholism Background: Life expectancy is greatly reduced in individuals presenting alcohol use disorders and chronic smoking. Literature studies suggest that common mechanisms may apply ...
    • Reyes Morales, Paola; Mora Cárdenas, Daniel (Universidad de Chile, 2017-12)
      mercado de construcción bajo Método Convencional, presenta una serie de ineficiencias y tiempos muertos asociados a condiciones climáticas (especialmente lluvias extensas), en algunas etapas de proceso constructivo. ...
    • Andrés, Sergio; Cárdenas, Sergio; Lecocq Parra, Claudio; Bravo, Javier; Greiner, Monika; Rojas, Paulina; Morales, Paola; Lara Peñaloza, Hernán; Fiedler Temer, Jenny (2006)
      Reduction in corticosterone by acute adrenalectomy (5 d) promotes apoptosis in dentate gyrus (DG) granular neurons, an effect concomitant with variations in the expression of the Bcl-2 gene family implicated in apoptotic ...
    • Karahanian, Eduardo; Quintanilla González, María Elena; Tampier de Jong, Lutske; Rivera Meza, Mario; Bustamante, Diego; González Lira, Víctor; Morales, Paola; Herrera-Marschitz Muller, Mario; Israel Jacard, Yedy (2011)
      Background: While the molecular entity responsible for the rewarding effects of virtually all drugs of abuse is known, that for ethanol remains uncertain. Some lines of evidence suggest that the rewarding effects of alcohol ...
    • Herrera-Marschitz Muller, Mario; Bustamante, Diego; Morales, Paola; Goiny, Michel (2007)
      The detailed anatomy of the monoamine pathways of the rat, first described by the students of Nils-Åke Hillarp in Sweden, provided the basis for a neurocircuitry targeted pharmacology, leading to important therapeutic ...
    • Israel Jacard, Yedy; Quintanilla González, María Elena; Ezquer, Fernando; Morales, Paola; Rivera Meza, Mario; Karahanian, Eduardo; Ezquer, Marcelo; Herrera Marschitz, Mario (Nature Publishing Group, 2019)
      Studies reviewed show that lentiviral gene therapy directed either at inhibiting the synthesis of brain acetaldehyde generated from ethanol or at degrading brain acetaldehyde fully prevent ethanol intake by rats bred for ...
    • Israel Jacard, Yedy; Ezquer, Fernando; Quintanilla González, María Elena; Morales, Paola; Ezquer, Marcelo; Herrera-Marschitz Muller, Mario (2017)
      © The Author 2016. Medical Council on Alcohol and Oxford University Press. All rights reserved. Study describes the blockade of relapse-like alcohol drinking by mesenchymal stem cells (MSCs). High alcohol-intake bred rats ...
    • Ezquer, Fernando; Quintanilla González, María Elena; Morales, Paola; Santapau, Daniela; Ezquer, Marcelo; Kogan Bocian, Marcelo; Salas Huenuleo, Edison; Herrera-Marschitz Muller, Mario; Israel Jacard, Yedy (Blackwell Publishing Ltd, 2018)
      © 2018 Society for the Study of AddictionChronic ethanol consumption leads to brain oxidative stress and neuroinflammation, conditions known to potentiate and perpetuate each other. Several studies have shown that ...
    • Morales, Paola; Simola, Nicola; Bustamante, Diego; Lisboa, Francisco; Fiedler, Jenny; Gebicke Haerter, Peter J.; Morelli, Micaela; Tasker, R. Andrew; Herrera-Marschitz Muller, Mario (2010)
      There is no established treatment for the long-term effects produced by perinatal asphyxia. Thus, we investigated the neuroprotection provided by nicotinamide against the effects elicited by perinatal asphyxia on hippocampus ...
    • Morales, Paola; Bustamante, Diego; Espina-Marchant, Pablo; Neira-Peña, Tanya; Gutiérrez-Hernández, Manuel A.; Allende-Castro, Camilo; Rojas Mancilla, Edgardo (2011)
      Perinatal asphyxia occurs still with great incidence whenever delivery is prolonged, despite improvements in perinatal care. After asphyxia, infants can suffer from short- to long-term neurological sequelae, their severity ...
    • Herrera-Marschitz Muller, Mario; Neira-Pena, Tanya; Rojas-Mancilla, Edgardo; Espina Marchant, Pablo; Esmar, Daniela; Perez, Ronald; Muñoz, Valentina; Gutierrez-Hernandez, Manuel; Rivera, Benjamin; Simola, Nicola; Bustamante, Diego; Morales, Paola; Gebicke-Haerter, Peter J. (Frontiers Research Foundation, 2014)
      Perinatal asphyxia constitutes a prototype of obstetric complications occurring when pulmonary oxygenation is delayed or interrupted. The primary insult relates to the duration of the period lacking oxygenation, leading ...
    • Espina Marchant, Pablo; Pinto Hamuy, Teresa; Bustamante, Diego; Morales, Paola; Herrera-Marschitz Muller, Mario (2009)
      Rats use place (allocentric) or stimulus-response (egocentric) learning strategies for foraging under ethological and/or experimental conditions, proposed to be conveyed by hippocampus or neostriatum, respectively. We ...
    • Lespay Rebolledo, Carolyne; Pérez Lobos, Ronald; Tapia Bustos, Andrea; Vio, Valentina; Morales, Paola; Herrera-Marschitz Muller, Mario (Springer New York LLC, 2018)
      © 2018, Springer Science+Business Media, LLC, part of Springer Nature. The present report evaluates the effect of global perinatal asphyxia on several parameters of oxidative stress and cell viability in rat brain tissue ...
    • Quintanilla González, María Elena; Rivera Meza, Mario; Berríos Cárcamo, Pablo; Bustamante, Diego; Buscaglia, Marianne; Morales, Paola; Karahanian, Eduardo; Herrera-Marschitz Muller, Mario; Israel Jacard, Yedy (Elsevier Inc., 2014)
      © 2014 Elsevier Inc.Salsolinol is formed non-enzymatically when ethanol-derived acetaldehyde binds to dopamine, yielding 2 distinct products, i.e., salsolinol and isosalsolinol. Early animal studies, revealing that salsolinol ...
    • Espina Marchant, Pablo; Pinto Hamuy, Teresa; Bustamante, Diego; Morales, Paola; Robles, Luis; Herrera-Marschitz Muller, Mario (Society of Biology of Chile, 2006)
      Place memory is relevant for exploration and forage behaviour. When food supply is dispersed, a win-shift has advantage over a win-stay strategy. In the Olton Octagonal Maze, the rat follows a win-shift strategy using ...