Browsing by Author "cd8b4659-9d34-4141-ab58-1a33b43b6ccf"

Now showing items 1-11 of 11

    • Angiotensin-(1-9) reduces cardiovascular and renal inflammation in experimental renin-independent hypertension 
      González, Leticia; Novoa, Ulises; Moya, Jackeline; Gabrielli, Luigi; Jalil Milad, Jorge; García Nannig, Lorena; Chiong Lay, Mario; Lavandero González, Sergio; Ocaranza, María Paz (Elsevier Inc., 2018)
      © 2018 Elsevier Inc. Hypertension-induced cardiovascular and renal damage can be mediated by activation of the renin-angiotensin-aldosterone system. There are different factors beyond renin-angiotensin-aldosterone system ...
    • Cardiotoxicidad inducida por tratamientos oncológicos. Fundamentos para la implementación de equipos de ... 
      Hameau, Rene; Gabrielli, Luigi; Garrido, Marcelo; Guzmán, Ana M.; Retamal, Ignacio; Vacarezza, María José; Greig, Douglas; Ocqueteau, Mauricio; Sanchez, Cesar; Pizarro, Marcela; Corvalan, Alejandro; Lavandero González, Sergio; Castro, Pablo F.; Martinez, Gonzalo (Sociedad Médica de Santiago, 2018-01)
      Recently, we have witnessed major improvements in cancer treatment. Early diagnosis and development of new therapies have reduced cancer-related mortality. However, these new therapies, along with greater patient survival, ...
    • Cardiotoxicity of anticancer therapies. Towards the implementation of cardio-oncology units Cardiotoxicidad ... 
      Hameau, Rene; Gabrielli, Luigi; Garrido, Marcelo; Guzmán, Ana María; Retamal, Ignacio; Vacarezza, María José; Greig, Douglas; Ocqueteau, Mauricio; Sánchez, César; Pizarro, Marcela; Corvalán, Alejandro; Lavandero González, Sergio; Castro, Pablo F.; Martínez, Gonzalo (Sociedad Medica de Santiago, 2018)
      © 2018, Sociedad Medica de Santiago. All rights reserved. Recently, we have witnessed major improvements in cancer treatment. Early diagnosis and development of new therapies have reduced cancer-related mortality. However, ...
    • Heart energy metabolism and its role in the treatment of heart failure Metabolismo energético del corazón ... 
      Castro, Pablo; Gabrielli, Luigi; Verdejo, Hugo; Greig, Douglas; Mellado, Rosemarie; Concepción, Roberto; Sepulveda, Luis; Vukasovic, José Luis; García Nannig, Lorena; Pizarro, Marcela; Pivet, Deisy; Carrillo, Constanza; Tapia, Fabiola; Navarro, Mario; Troncoso, Rodrigo; Baraon (2010)
      It is unknown why heart failure progresses even when patients are treated with the best therapy available. Evidences suggest that heart failure progression is due to loss of neurohumoral blockade in advanced stages of the ...
    • Inflammation and endothelial dysfunction in patients with chronic heart failure Inflamación y disfunción ... 
      Greig, Douglas; Castro, Pablo; Gabrielli, Luigi; Miranda, Rodrigo; Verdejo, Hugo; Alcaíno Gálvez, Hernán Alejandro; Bustos, Carlos; Chiong Lay, Mario; Godoy, Iván; Mellado, Rosemarie; García Nannig, Lorena; Salas, Daniela; Vivar, Raúl; Vukasovic, José Luis; Concepción, Roberto; Díaz Araya, Guillermo (2008)
      Background: In chronic heart failure (CHF), endothelial dysfunction (ED) is a consequence of an imbalance of vascular tone regulating substances. The relationship between ED and inflammation has not been fully investigated. ...
    • Influence of gender on right ventricle adaptation to endurance exercise: an ultrasound two-dimensional ... 
      Sanz-de la Garza, Maria; Giraldeau, Geneviève; Marin, Josefa; Grazioli, Gonzalo; Esteve, Montserrat; Gabrielli, Luigi; Brambila, Carlos; Sanchis, Laura; Bijnens, Bart; Sitges, Marta (Springer Verlag, 2017)
      © 2017, Springer-Verlag Berlin Heidelberg. Background: Characteristic right ventricle (RV) remodelling is related to endurance exercise in male athletes (MAs), but data in female athletes (FAs) are scarce. Our aim was to ...
    • Myocardial lipids and creatine measured by magnetic resonance spectroscopy among patients with heart failure ... 
      Winter, José Luis; Castro, Pablo; Meneses, Luis; Chalhub, Mónica; Verdejo, Hugo; Greig, Douglas; Gabrielli, Luigi; Chiong Lay, Mario; Concepción, Roberto; Mellado, Rosemarie; Hernández, Claudia; Uribe, Sergio; Lavandero González, Sergio (2010)
      Background: Heart failure (HF) is characterized, among other features, by the development of alterations in myocardial energy metabolism, involving a decrease in glucose utilization and increased free fatty acid uptake by ...
    • Protection of the myocardium against ischemia/reperfusion injury by angiotensin-(1–9) through an AT2R and ... 
      Mendoza Torres, Evelyn; Riquelme, Jaime A.; Vielma, Alejandra; Sagredo, Andrea Ramirez; Gabrielli, Luigi; Bravo Sagua, Roberto; Jalil Milad, Jorge; Rothermel, Beverly A.; Sánchez, Gina; Ocaranza, María Paz; Lavandero González, Sergio (Academic Press, 2018)
      © 2018 Elsevier Ltd Angiotensin-(19), a peptide of the non-classical renin angiotensin system, has been shown to prevent and revert hypertension and cardiac hypertrophy. We hypothetized that systemic delivery of angiotensin-(1–9) ...
    • Rho kinase cascade activation in circulating leukocytes in patients with diabetes mellitus type 2 
      Ocaranza, María Paz; Valderas, Patricio; Moya, Jackeline; Gabrielli, Luigi; Godoy, Iván; Córdava, Samuel; Mac Nab, Paul; García Nannig, Lorena; Farías, Luis; Jalil, Jorge E. (BMC, 2020)
      BackgroundThe intracellular ROCK signaling pathway is an important modulator of blood pressure and of cardiovascular and renal remodeling when Rho-kinase activity is increased. Besides, in preclinical models of diabetes, ...
    • Role of interleukin-6 in vascular health and disease 
      Villar Fincheira, Paulina; Sanhueza Olivares, Fernanda; Norambuena Soto, Ignacio; Cancino Arenas, Nicole; Hernández Vargas, Felipe; Troncoso Cotal, Rodrigo; Gabrielli, Luigi; Chiong Lay, Mario (Frontiers Media, 2021)
      IL-6 is usually described as a pleiotropic cytokine produced in response to tissue injury or infection. As a pro-inflammatory cytokine, IL-6 activates innate and adaptative immune responses. IL-6 is released in the innate ...
    • Survival of patients with pulmonary arterial hypertension after the advent of specific pulmonary vasodilator ... 
      Herrera, Sebastián; Gabrielli, Luigi A.; Paredes, Alejandro; Saavedra, Rodrigo; Paz Ocaranza, María; Fuentes Sepúlveda, Pablo Ignacio; Donoso, Hernán; López, Leonel; Verdejo, Hugo; Baraona, Fernando (Soc. Médica Santiago, 2016)
      Background: Pulmonary arterial hypertension (PAH) is a rare and progressive disease. Long-term survival remains poor despite of advances in specific vasodilator therapy. Aim: To describe the survival rate in a cohort of ...