Browsing by Author "cda11e98-d7c7-486b-99ac-947e8aea7d09"
Now showing items 1-3 of 3
-
A functional IL1RL1 variant regulates corticosteroid-induced sST2 expression in ulcerative colitis Díaz Jiménez, David; Núñez, Lucía; Fuente, Marjorie de la; Dubois Camacho, Karen; Sepulveda, Hugo; Montecino, Martin; Torres Riquelme, Alejandro; García González, Paulina; Chnaiderman Figueroa, Jonás; Vossenkamper, Anna; MacDonald, Thomas T.; Simian, Daniela; González Burgos, María Julieta; Cidlowski, John A.; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (Nature Publishing Group, 2017)The ST2/IL33 signalling pathway has been associated with ulcerative colitis (UC). ST2, encoded by the IL1RL1 gene, is expressed as both a membrane-anchored receptor (ST2L) activated by IL33 and as a soluble receptor (sST2) ...
-
Dubois Camacho, Karen; Ottum, Payton A.; Franco Muñoz, Daniel; Fuente, Marjorie de la; Torres Riquelme, Alejandro; Díaz Jiménez, David; Olivares Morales, Mauricio; Astudillo, Gonzalo; Quera Pino, Rodrigo; Hermoso Ramello, Marcela (Baishideng Publishing Group, 2017)Inflammatory bowel diseases (IBDs), such as ulcerative colitis and Crohn's disease, are chronic pathologies associated with a deregulated immune response in the intestinal mucosa, and they are triggered by environmental ...
-
Álvarez, Karin; Orellana, Paulina; Fuente, Marjorie de la; Canales, Tamara; Pinto, Eliana; Heine,; Solar, Benjamín; Hurtado, Claudia; Moller, Pal; Kronberg, Udo; Zárate, Alejandro José; Domínguez Valentín, Mev; López Köstner, Francisco (MDPI, 2020)Lynch syndrome (LS) is associated with the highest risk of colorectal (CRC) and several extracolonic cancers. In our e ort to characterize LS families from Latin America, this study aimed to describe the spectrum of ...