Browsing by Author "cfd84195-bcd1-434f-b786-3d83f70132e3"

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    • Chronic bryostatin‑1 rescues autistic and cognitive phenotypes in the fragile X mice 
      Cogram, Patricia; Alkon, Daniel L.; Crockford, David; Deacon, Robert M.J.; Hurley, Michael J.; Altimiras, Francisco; Sun, Miao‑Kun; Tranfaglia, Michael (Nature, 2020)
      Fragile X syndrome (FXS), an X-chromosome linked intellectual disability, is the leading monogenetic cause of autism spectrum disorder (ASD), a neurodevelopmental condition that currently has no specific drug treatment. ...
    • The long-lived Octodon degus as a rodent drug discovery model for Alzheimer's and other age-related diseases 
      Hurley, Michael J.; Deacon, Robert M.J.; Beyer, Katrin; Ioannou, Elena; Ibáñez, Agustin; Teeling, Jessica L.; Cogram, Patricia (Elsevier Inc., 2018)
      © 2018 Elsevier Inc. Alzheimer's disease (AD) is a multifactorial progressive neurodegenerative disease. Despite decades of research, no disease modifying therapy is available and a change of research objectives and/or ...