Browsing by Author "d2ba5a3e-88d3-435d-90a8-ff8d2b01eec0"
Now showing items 1-4 of 4
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Lourido, Fernanda; Quenti, Daniela; Salgado Canales, Daniela; Tobar Bachler, Nicolás (Nature, 2021)Insulin resistance is a hallmark of type 2 diabetes resulting from the confluence of several factors, including genetic susceptibility, inflammation, and diet. Under this pathophysiological condition, the dysfunction of ...
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Kallens, Violeta; Tobar Bachler, Nicolás; Molina, Jessica; Bidegain, Arantzazú; Smith, Patricio C.; Porras Espinoza, Omar; Martínez, Jorge (Wiley, 2017)Chronic inflammation and metabolic reprogramming have been proposed as hallmarks of cancer development. Currently, many of the functional clues between these two phenomena are studied under the integrative view of functional ...
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Tobar Bachler, Nicolás; Porras Espinoza, Omar; Smith, Patricio C.; Barros, L. Felipe; Martínez, Jorge (Wiley, 2017)Hyperglycemia is a risk factor for a variety of human cancers. Increased access to glucose and that tumor metabolize glucose by a glycolyticprocess even in the presence of oxygen (Warburg effect), provide a framework to ...
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Páez, Jassir; Hernández, Romina; Espinoza, Javier; Rojas, Leticia; Martínez, Constanza E.; Tobar Bachler, Nicolás; Martínez Winkler, Jorge; Smith, Patricio C. (Wiley, 2020)Background and objective: Aging is characterized by a decline in tissue structure and function that may be explained by the development of cellular senescence. However, the acquisition of specific phenotypic responses in ...