Now showing items 1-15 of 15

    • Carrillo, Ileana; Castillo, Christian; Droguett, Daniel; Muñoz, Lorena; Liempi, Ana; Maya Arango, Juan; Galanti Garrone, Norbel; Kemmerling Weis, Ulrike (2016)
      Congenital Chagas’ disease is caused by the haemophlagelated protozoan Trypanosoma cruzi (T. cruzi), which is able to cross the placental barrier and infect both the placenta and fetus. However, congenital transmission ...
    • Medina, Lisvaneth; Castillo, Christian; Liempi, Ana; Herbach, Mathias; Cabrera, Gonzalo; Valenzuela, Lucía; Galanti Garrone, Norbel; de los Angeles Curto, María; Schijman, Alejandro G.; Kemmerling Weis, Ulrike (Elsevier B.V., 2018)
      © 2018 Elsevier B.V. Congenital Chagas disease, caused by Trypanosoma cruzi (T. cruzi), has become epidemiologically relevant. The probability of congenital transmission depends on the maternal and developing fetal/newborn ...
    • Rojas, Diego A.; Urbina, Fabiola; Moreira Ramos, Sandra; Castillo, Christian; Kemmerling Weis, Ulrike; Lapier, Michel; Maya Arango, Juan; Solari Illescas, Aldo; Maldonado Maldonado, Edio (Public Library Science, 2018)
      Trypanosoma cruzi is exposed during its life to exogenous and endogenous oxidative stress, leading to damage of several macromolecules such as DNA. There are many DNA repair pathways in the nucleus and mitochondria ...
    • Rojas, Diego A.; Urbina, Fabiola; Moreira Ramos, Sandra; Castillo, Christian; Kemmerling Weis, Ulrike; Lapier, Michel; Maya Arango, Juan; Solari Illescas, Aldo; Maldonado, Edio (Public Library of Science, 2018)
      © 2018 Rojas et al. Trypanosoma cruzi is exposed during its life to exogenous and endogenous oxidative stress, leading to damage of several macromolecules such as DNA. There are many DNA repair pathways in the nucleus and ...
    • González Herrera, Fabiola; Cramer, Allysson; Pimentel, Pollyana; Castillo, Christian; Liempi, Ana; Kemmerling Weis, Ulrike; Machado, Fabiana S.; Maya Arango, Juan (American Society Microbiology, 2017)
    • Castillo, Christian; Carrillo, Ileana; Libisch, Gabriela; Juiz, Natalia; Gabriel Schijman, Alejandro; Robello, Carlos; Kemmerling Weis, Ulrike (BioMed Central Ltd., 2018)
      © 2018 The Author(s). Background: Chagas disease is caused by Trypanosoma cruzi, a parasite endemic to Latin America. Most infections occur in children by vector or congenital transmission. Trypanosoma cruzi establishes a ...
    • Díaz Viraque, Florencia; Chiribao, María Laura; Trochine, Andrea; González Herrera, Fabiola; Castillo, Christian; Liempi, Ana; Kemmerling Weis, Ulrike; Diego Maya, Juan; Robello, Carlos (Frontiers media SA, 2018)
      The discovery that trypanosomatids, unicellular organisms of the order Kinetoplastida, are capable of synthesizing prostaglandins raised questions about the role of these molecules during parasitic infections. Multiple ...
    • Molina Berríos, Alfredo Enrique; Campos Estrada, Carolina; Henriquez, Natalia; Faúndez, Mario; Torres, Gloria; Castillo, Christian; Escanilla, Sebastián; Kemmerling Weis, Ulrike; Morello Casté, Antonio; López Muñoz, Rodrigo; Maya Arango, Juan (Public Library of Science, 2013)
      Chagas' disease, produced by Trypanosoma cruzi, affects more than 8 million people, producing approximately 10,000 deaths each year in Latin America. Migration of people from endemic regions to developed countries has ...
    • González Herrera, Fabiola; Cramer, Allysson; Pimentel, Pollyana; Castillo, Christian; Liempi, Ana; Kemmerling Weis, Ulrike; Machado, Fabiana S.; Maya Arango, Juan (American Society for Microbiology, 2017)
      Current treatments for chronic Chagas cardiomyopathy, a disease with high mortality rates and caused by the protozoan Trypanosoma cruzi, are unsatisfactory. Myocardial inflammation, including endothelial activation, is ...
    • Muñoz, Lorena; Castillo, Christian; Carrillo, Ileana; Salinas, Andrea; Liempi, Ana; Droguett, Daniel; Maya Arango, Juan; Galanti Garrone, Norbel; Kemmerling Weis, Ulrike (2016)
      Trypanosoma cruzi (T. cruzi), the causative agent of Chagas disease, and Toxoplasma gondii (T. gondii), responsible for Toxoplasmosis are two parasites that can cross the placental barrier. T. cruzi and T. gondii present ...
    • Castillo, Christian; Muñoz, Lorena; Carrillo, Ileana; Droguett, Daniel; Liempi, Ana; Astudillo, Javier; Maya Arango, Juan; Galanti Garrone, Norbel; Kemmerling Weis, Ulrike (2016)
      Congenital Chagas’ disease, caused by the protozoan Trypanosoma cruzi (T. cruzi), is one of the major public health concerns in Latin America where more than one million women in fertile age are infected. During ...
    • Medina, Lisvaneth; Castillo Rivas, Christian; Liempi, Ana; Guerrero Muñoz, Jesús; Rojas Pirela, Maura; Maya Arango, Juan Diego; Prieto, Humberto; Kemmerling Weis, Ulrike (Frontiers Media, 2020)
      Trypanosoma cruzi and Toxoplasma gondii are two parasites than can be transmitted from mother to child through the placenta. However, congenital transmission rates are low for T. cruzi and high for T. gondii. Infection ...
    • Droguett, Daniel; Carrillo, Ileana; Castillo, Christian; Gómez, Fresia; Negrete, Miguel; Liempi, Ana; Muñoz, Lorena; Kemmerling Weis, Ulrike; Galanti Garrone, Norbel; Maya Arango, Juan; Droguett, Daniel (Academic Press Inc., 2017)
      © 2016 Elsevier Inc.Congenital transmission of Trypanosoma cruzi (T. cruzi) is partially responsible for the progressive globalization of Chagas disease. During congenital transmission the parasite must cross the placental ...
    • Liempi, Ana; Castillo, Christian; Cerda, Mauricio; Droguett, Daniel; Duaso, Juan; Barahona, Katherine; Hernández, Ariane; Díaz Luján, Cintia; Fretes, Ricardo; Härtel, Steffen; Kemmerling Weis, Ulrike (Elsevier, 2015)
      © 2014 Elsevier B.V.Chagas disease is an endemic, neglected tropical disease in Latin America that is caused by the protozoan parasite Trypanosoma cruzi. In vitro models constitute the first experimental approach to study ...
    • Liempi, Ana; Castillo, Christian; Cerda, Mauricio; Droguett, Daniel; Duaso, Juan; Barahona, Katherine; Hernández, Ariane; Díaz Luján, Cintia; Fretes, Ricardo; Härtel, Steffen; Kemmerling Weis, Ulrike (Elsevier, 2015)
      © 2014 Elsevier B.V.Chagas disease is an endemic, neglected tropical disease in Latin America that is caused by the protozoan parasite Trypanosoma cruzi. In vitro models constitute the first experimental approach to study ...