Browsing by Author "d8f2a7fc-42df-4ef6-b93c-1b290e4dad9c"
Now showing items 1-15 of 15
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Blondel, Carlos J.; Jiménez, Juan C.; Contreras, Inés; Santiviago, Carlos A. (2009)Background: The recently described Type VI Secretion System (T6SS) represents a new paradigm of protein secretion in bacteria. A number of bioinformatic studies have been conducted to identify T6SS gene clusters in the ...
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Martinić, Mara; Hoare, Anilei; Contreras, Inés; Álvarez, Sergio A. (2011)Shigella flexneri is endemic in most underdeveloped countries, causing diarrheal disease and dysentery among young children. In order to reach its target site, the colon, Shigella must overcome the acid environment of the ...
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Blondel, Carlos J.; Yang, Hee Jeong; Castro, Benjamín; Chiang, Sebastián; Toro, Cecilia S.; Zaldïvar, Mercedes; Contreras, Inés; Andrews-Polymenis, Helene L.; Santiviago, Carlos A. (2010)Salmonella Gallinarum is a pathogen with a host range specific to poultry, while Salmonella Enteritidis is a broad host range pathogen that colonizes poultry sub-clinically but is a leading cause of gastrointestinal ...
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Blondel, Carlos J.; Jiménez, Juan C.; Leiva, Lorenzo E.; álvarez, Sergio A.; Pinto, Bernardo I.; Contreras, Francisca; Pezoa, David; Santiviago Cid, Carlos; Contreras, Inés (American Society for Microbiology, 2015)
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Espinoza, Rodrigo A.; Silva Valenzuela, Cecilia A.; Amaya, Fernando A.; Urrutia, ítalo M.; Contreras, Inés; Santiviago, Carlos A. (BioMed Central, 2017)Background: Salmonella pathogenicity island (SPI)-13 is conserved in many serovars of S. enterica, including S. Enteritidis, S. Typhimurium and S. Gallinarum. However, it is absent in typhoid serovars such as S. Typhi and ...
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Saldías, M. Soledad; Patel, Kinnari; Marolda, Cristina L.; Bittner, Mauricio; Contreras, Inés; Valvano, Miguel A. (2008)WbaP is a membrane enzyme that initiates O antigen synthesis in Salmonella enterica by catalysing the transfer of galactose 1-phosphate (Gal-1-P) onto undecaprenyl phosphate (Und-P). WbaP possesses at least three predicted ...
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Ibrahim, Muhammad; Shi, Yu; Qiu, Hui; Li, Bin; Jabeen, Amara; Li, Liping; Liu, He; Kube, Michael; Xie, Guanlin; Wang, Yanli; Blondel, Carlos; Santiviago Cid, Carlos; Contreras, Inés; Sun, Guochang (Public Library of Science, 2013)
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Silva Valenzuela, Cecilia; Velásquez, Felipe; Peñailillo, Johany; Garcías Papayani, H éctor; Fernández, Paulina; Tobar, Pía; Contreras, Inés; Santiviago Cid, Carlos; Álvarez Armijo, Sergio (Elsevier, 2016)Lipopolysaccharide (LPS) consists of three covalently linked domains: the lipid A, the core region and the O antigen (OAg), consisting of repeats of an oligosaccharide. Salmonella enterica serovar Enteritidis (S. Enteritidis) ...
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Rodas, Paula I.; Contreras, Inés; Mora, Guido C. (2010)Objectives: To investigate the association between the presence of a genetic island inserted within the sapABCDF operon of Salmonella Typhi and the susceptibility to antimicrobial peptides. Methods: Genetics and bioinformatics ...
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Silva Valenzuela, Cecilia A.; Desai, Prerak; Molina Quiroz, Roberto C.; Pezoa, David; Zhang, Yong; Porwollik, Steffen; Zhao, Ming; Hoffman, Robert M.; Contreras, Inés; Santiviago Cid, Carlos; McClelland, Michael (Impact Journals, 2016)Therapeutic attenuated strains of Salmonella Typhimurium target and eradicate tumors in mouse models. However, the mechanism of S. Typhimurium for tumor targeting is still poorly understood. We performed a high-throughput ...
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Santiviago, Carlos A.; Blondel, Carlos J.; Quezada, Carolina P.; Silva, Cecilia A.; Tobar, Pia M.; Porwollik, Steffen; McClelland, Michael; Andrews-Polymenis, Helene L.; Toro, Cecilia S.; Zaldívar, Mercedes; Contreras, Inés (2010)Salmonella enterica serovar Enteritidis has emerged as a major health problem worldwide in the last few decades. DNA loci unique to S. Enteritidis can provide markers for detection of this pathogen and may reveal pathogenic ...
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Carter, Javier A.; Jiménez, Juan C.; Zaldívar, Mercedes; Álvarez, Sergio A.; Marolda, Cristina L.; Valvano, Miguel A.; Contreras, Inés (2009)The lipopolysaccharide O antigen of Shigella flexneri 2a has two preferred chain lengths, a short (S-OAg) composed of an average of 17 repeated units and a very long (VL-OAg) of about 90 repeated units. These chain length ...
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Hoare, Anilei; Bravo, Denisse; Martinić, Mara; Valvano, Miguel; Contreras, Inés; Álvarez, Sergio (2012)Shigella flexneri causes bacillary dysentery in humans. Essential to the establishment of the disease is the invasion of the colonic epithelial cells. Here we investigated the role of the lipopolysaccharide (LPS) O antigen ...
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Bravo, Denisse; Blondel, Carlos J.; Hoare, Anilei; Leyton Campos, Lisette; Valvano, Miguel A.; Contreras, Inés (2011)The cystic fibrosis transmembrane conductance regulator (CFTR) has been proposed as an epithelial cell receptor for the entry of Salmonella Typhi but not Salmonella Typhimurium. The bacterial ligand recognized by CFTR is ...
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Blondel, Carlos J.; Jiménez, Juan C.; Leiva, Lorenzo E.; Álvarez Armijo, Sergio Aníbal; Pinto, Bernardo I.; Contreras, Francisca; Pezoa, David; Santiviago Cid, Carlos; Contreras, Inés (American Society for Microbiology, 2013-04)Salmonella enterica serotype Gallinarum is the causative agent of fowl typhoid, a disease characterized by high morbidity and mortality that causes major economic losses in poultry production. We have reported that S. ...