Browsing by Author "daf08ef4-deca-49ff-a646-86cb39460d07"

Now showing items 1-7 of 7

    • Cytotoxicity and trypanocidal activity of nifurtimox encapsulated in ethylcyanoacrylate nanoparticles 
      Sánchez, Gittith; Cuellar, Daniela; Zulantay Alfaro, Inés; Gajardo, Marta; González-Martin, Guillermo (Society of Biology of Chile, 2002)
      The aim of the present study was to study the trypanocidal activity of nanoparticles loaded with nifurtimox in comparison with the free drug against Trypanosoma cruzi, responsible for Chagas' disease. Ethylcyanoacrylate ...
    • Dissimilar distribution of Trypanosoma cruzi clones in humans after chemotherapy with allopurinol and itraconazole 
      Coronado, Ximena; Zulantay Alfaro, Inés; Rozas, Marlene; Apt Baruch, Werner; Sánchez, Gittith; Rodríguez Borges, Jorge; Ortiz Zúñiga, Sylvia; Solari Illescas, Aldo (OXFORD UNIV PRESS, 2006-07)
      Objectives: The aim of this work was to study the distribution of Trypanosoma cruzi clones after treatment failure with itraconazole or allopurinol in infected humans. Methods: Blood samples from treated and untreated ...
    • Microsatellite marker analysis shows differentiation among Trypanosoma cruzi populations of peripheral blood ... 
      Venegas, Juan; Miranda, Sandra; Coñoepan, William; Pîchuantes, Sergio; Jercic, María Isabel; González, Christian; Gajardo, Marta; Apt Baruch, Werner; Arribada, Arturo; Sánchez, Gittith (2010)
      To investigate whether Trypanosoma cruzi populations found in chagasic cardiopathic and non-cardiopathic patients are genetically differentiated, three molecular microsatellite markers were analysed. This analysis was also ...
    • Phylogenetic analysis of microsatellite markers further supports the two hybridization events hypothesis ... 
      Venegas, Juan; Coñoepan, William; Pichuantes, Sergio; Miranda, Sandra; Jercic, María Isabel; Gajardo, Marta; Sánchez, Gittith (2009)
      To better understand the evolution of the etiologic agent of Chagas disease, we cloned and sequenced 25 alleles from five Tripanosoma cruzi microsatellite markers. The study of the sequences showed highly conserved alleles ...
    • Trypanosoma cruzi calreticulin topographical variations in parasites infecting murine macrophages 
      González, Andrea; Valck, Carolina; Sánchez, Gittith; Härtel, Steffen; Mansilla, Jorge; Ramírez, Galia; Fernández, María Soledad; Arias, José; Galanti Garrone, Norbel; Ferreira, Arturo (American Society of Tropical Medicine and Hygiene, 2015)
      Trypanosoma cruzi calreticulin (TcCRT), a 47-kDa chaperone, translocates from the endoplasmic reticulum to the area of flagellum emergence. There, it binds to complement components C1 and mannan-binding lectin (MBL), thus ...
    • Use of polymerase chain reaction (PCR) and hybridization assays to detect trypanosoma cruzi in chronic ... 
      Zulantay Alfaro, Inés; Honores, Patricia; Solari Illescas, Aldo; Apt Baruch, Werner; Ortíz, Sylvia; Osuna, Antonio; Rojas, Antonio; López, Bernardo; Sánchez, Gittith (2004)
      The presence of Trypanosoma cruzi in chronic chagasic patients with negative xenodiagnosis (XD) after 6 years following completion of therapy with either itraconazole or allopurinol was assessed by polymerase chain reaction ...
    • Variation in Trypanosoma cruzi clonal composition detected in blood patients and xenodiagnosis triatomines: ... 
      Coronado, Ximena; Zulantay Alfaro, Inés; Albrecht, Helena; Rozas, Marlene; Apt Baruch, Werner; Ortiz Zúñiga, Sylvia; Rodríguez Borges, Jorge; Sánchez, Gittith; Solari Illescas, Aldo (AMER SOC TROP MED & HYGIENE, 2006-06)
      To identify Trypanosoma cruzi clones from chronically infected individuals, they were transferred to triatomines by the xenodiagnosis test (XD) with Triatoma infestans. Polymerase chain reaction (PCR) and hybridization ...