Browsing by Author "db02cc60-1ed5-4272-ace3-60e2fe1f0b9d"

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    • ER stress signaling and neurodegeneration: At the intersection between Alzheimer's disease and Prion-related ... 
      Torres, Mauricio; Matamala, José Manuel; Durán Aniotz, Claudia; Cornejo, Víctor Hugo; Foley, Andrew; Hetz Flores, Claudio (Elsevier, 2015)
      © 2014 Elsevier B.V. Alzheimer's and Prion diseases are two neurodegenerative conditions sharing different pathophysiological characteristics. Disease symptoms are associated with the abnormal accumulation of protein ...
    • IRE1 signaling exacerbates Alzheimer's disease pathogenesis 
      Durán Aniotz, Claudia; Cornejo, Victor Hugo; Espinoza, Sandra; Ardiles, Alvaro O.; Medinas Bilches, Danilo; Salazar, Claudia; Foley, Andrew; Gajardo, Ivana; Thielen, Peter; Iwawaki, Takao; Scheper, Wiep; Soto, Claudio; Palacios, Adrian G.; Hoozemans, Jeroen J. M.; Hetz Flores, Claudio (Springer, 2017)
      Altered proteostasis is a salient feature of Alzheimer's disease (AD), highlighting the occurrence of endoplasmic reticulum (ER) stress and abnormal protein aggregation. ER stress triggers the activation of the unfolded ...