Browsing by Author "dc4bbee3-dbe0-46d3-95c3-960c62894220"

Now showing items 1-12 of 12

    • Aged blood factors decrease cellular responses associated with delayed gingival wound repair 
      Saldías, María Paz; Fernández, Christian; Morgan, Alejandra; Díaz, Catalina; Morales, Diego; Jana, Fabian; Gómez Gallo, Alvaro; Silva, Alonso; Briceño, Fernanda; Oyarzún, Alejandro; Maldonado Caniulao, Felipe; Cerda Arancibia, Óscar; Smith, Patricio C.; Cáceres, Mónica (Public Library Science, 2017)
      Aging is a gradual biological process characterized by a decrease in cell and organism functions. Gingival wound healing is one of the impaired processes found in old rats. Here, we studied the in vivo wound healing process ...
    • Effect of sevoflurane and propofol on tourniquet-induced endothelial damage: a pilot randomized controlled ... 
      Maldonado Caniulao, Felipe; Morales Requena, Diego; Gutiérrez Rojas, Rodrigo; Barahona Vásquez, Maximiliano; Cerda Arancibia, Óscar; Cáceres Lluch, Mónica (BMC, 2020)
      Background The glycocalyx layer is a key structure in the endothelium. Tourniquet-induced ischemic periods are used during orthopedic surgery, and the reactive oxygen species generated after ischemia-reperfusion may mediate ...
    • Inhibition of the 3-Hydroxy-3-Methyl-Glutaryl-CoA Reductase Induces Orofacial Defects in Zebrafish 
      Signore Ahumada, Iskra; Jerez, Carolina; Figueroa, Diego; Suazo Sanhueza, José Lorenzo; Marcelain Cubillos, Katherine; Cerda Arancibia, Óscar; Colombo Flores, Alicia (Wiley, 2016)
      Background: Orofacial clefts (OFCs) are common birth defects, which include a range of disorders with a complex etiology affecting formation of craniofacial structures. Some forms of syndromic OFCs are produced by defects ...
    • K+ Channel Tetramerization Domain 5 (KCTD5) Protein Regulates Cell Migration, Focal Adhesion Dynamics and ... 
      Canales, Jimena; Cruz, Pablo; Villacura Díaz, Nicolás Esteban; Riquelme, Denise; Leiva Salcedo, Elias; Cerda Arancibia, Óscar (MDPI, 2020)
      Cell migration is critical for several physiological and pathophysiological processes. It depends on the coordinated action of kinases, phosphatases, Rho-GTPases proteins, and Ca2+ signaling. Interestingly, ubiquitination ...
    • KCTD5 and ubiquitin proteasome signaling are required for Helicobacter pylori adherence 
      Alvarez, Alhejandra; Uribe, Felipe; Canales, Jimena; Romero, Cristóbal; Soza, Andrea; Peña, María A.; Antonelli Anativia, Juan; Almarza, Oscar; Cerda Arancibia, Óscar; Toledo Araya, Héctor (Frontiers Media SA, 2017)
      In order to establish infection, bacterial pathogens modulate host cellular processes by using virulence factors, which are delivered from the bacteria to the host cell leading to cellular reprogramming. In this context, ...
    • KCTD5, a novel TRPM4-regulatory protein required for cell migration as a new predictor for breast cancer prognosis 
      Rivas, José; Díaz, Nicolás; Silva, Ian; Morales, Dana; Lavanderos, Boris; Álvarez, Alhejandra; Saldías Maulén, María Paz; Pulgar Pulgar, Eduardo; Cruz Núñez, Pablo; Maureira, Diego; Flores Utreras, Guillermo; Colombo Flores, Alicia; Blanco, Constanza; Contreras Muñoz, Héctor; Jaña, Fabián; Gallegos Méndez, Iván; Concha Nordemann, Miguel; Vergara Jaque, Ariela; Poblete, Horacio; González, Wendy; Varela Lekanda, Diego; Trimmer, James; Cáceres Lluch, Mónica Andrea; Cerda Arancibia, Óscar (Wiley, 2020)
      Transient receptor potential melastatin 4 (TRPM4) is a Ca2+-activated nonselective cationic channel that regulates cell migration and contractility. Increased TRPM4 expression has been related to pathologies, in which ...
    • Role of KCTD5 during Helicobacter pylori infection in gastric epithelial cells 
      Toledo Araya, Héctor; Alvarez A., José Miguel; Uribe, F.; Canales, J.; Canto, N.; Cerda Arancibia, Óscar (Wiley, 2017)
    • The microtubule-associated end binding proteins regulate the ER exporting and trafficking of TRPM4 channels 
      Blanco, C.; Aldunate, I.; Canales, J.; Rivas, J.; Riquelme, D.; Morales, D.; Silva, I.; Alvarez, A.; Vergara, A.; Poblete, H.; Romero, A.; Leiva, E.; Gonzalez, W.; Varela, D.; Cáceres Lluch, Mónica Andrea; Cerda Arancibia, Óscar (American Society Cell Biology, 2017)
    • TRP channels regulation of Rho GTPases in brain context and diseases 
      Lavanderos, Boris; Silva, Ian; Cruz, Pablo; Orellana Serradell, Octavio; Saldías, María Paz; Cerda Arancibia, Óscar (Frontiers Media, 2020)
      Neurological and neuropsychiatric disorders are mediated by several pathophysiological mechanisms, including developmental and degenerative abnormalities caused primarily by disturbances in cell migration, structural ...
    • TRPM Channels in Human Diseases 
      Jiménez, Ivanka; Prado, Yolanda; Marchant, Felipe; Otero, Carolina; Eltit, Felipe; Cabello Verrugio, Claudio; Cerda Arancibia, Óscar; Simón, Felipe (MDPI, 2020)
      The transient receptor potential melastatin (TRPM) subfamily belongs to the TRP cation channels family. Since the first cloning of TRPM1 in 1989, tremendous progress has been made in identifying novel members of the TRPM ...
    • TRPM4 activation by chemically- and oxygen deprivation-induced ischemia and reperfusion triggers neuronal death 
      Leiva Salcedo, Elias; Riquelme, Denise; Cerda Arancibia, Óscar; Stutzin Schottlander, Andrés (Taylor & Francis, 2017)
      Cerebral ischemia-reperfusion injury triggers a deleterious process ending in neuronal death. This process has two components, a glutamate-dependent and a glutamate-independent mechanism. In the glutamate-independent ...
    • Young blood serum increased cellular response associated to wound healing in old rats 
      Cáceres Lluch, Mónica Andrea; Saldías, M.; Fernández, C.; Folli, V.; Cerda Arancibia, Óscar (American Society Cell Biology, 2017)